<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Mitsuya (2006)
Title N88D facilitates the co-occurrence of D30N and L90M and the development of multidrug resistance in HIV type 1 protease following nelfinavir treatment failure.
Citation ARHR
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 27
NumPts 22
Subtype B


Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
CA1329 CA55163 IDV, NFV, SQV, RTV, Unknown 139 D30N, I84V, L90M L10F, L33F, K43T, N88D I15V, E35D, M36L, N37E, D60E, I62V, L63P, I93L  
CA14264 CA33428 NFV 184 D30N, L90M L10FI, N88D Q7E, I13V, R41K, K45R, L63P, V77I, I93L  
CA14364 CA33594 Unknown  D30N, M46L, L90M N88D N37S, R41K, I62V, L63P, I64V, V77I, I93L  
CA14386 CA33630 Unknown  D30DN, L90LM N88ND R57K, L63P, E65D, A71V  
CA1449 CA3872 Unknown    I15V, E35D, N37E, R57K, D60DE, L63P, I72IT  
  CA17507 Unknown    I15V, E35D, N37E, R57K, D60E, L63P  
  CA10674 Unknown    I15V, E35D, N37E, I62V, L63P  
CA14576 CA33951 Unknown  D30DN, I54IV, L90LM Q58QE, N88ND I13IV, I15IV, K20I, E35EG, M36MI, W42Y, L63P, K70KT, A71AV  
CA16171 CA38480 IDV, NFV 244 D30DN, M46MI, L90LM T74TP, N88ND I13V, R57K, D60E, I62V, L63P, A71V, V77I, I93L  
CA16266 CA38682 Unknown  D30N, L90LM N88D L10LI, I13V, K45R, L63P, I64IL, K70R, A71AT, V77I, I93IL  
CA16485 CA39157 Unknown, APV, LPV, RTV 65   K14R, I15V, N37E, L63PS, V82VI, I93L  
  CA42779 Unknown, APV, LPV, RTV, ATV 73 D30N, I54V, I84V, L90M L10F, L33F, N88D I13V, I15V, E35D, M36I, N37E, I62V, L63P, L89F, I93L  
  CA57855 Unknown, APV, LPV, RTV, ATV 117 D30DN, I54IL, I84IV, L90LM L10LF, L33LF, K43KT, N88ND I13IV, K14KR, I15V, E35ED, M36I, N37E, R41RK, I62IV, L63P, L89LF, I93L A71AS 
CA21019 CA48347 NFV, SQV, RTV 315 D30N, I84V, L90M L33F, N88D I13V, I15V, L63P, A71T  
CA22061 CA51030 NFV 42 D30N, L90M N88D I13V, E35D, M36I, I62V, L63P, I64V  
CA22062 CA51032 IDV, NFV 385 D30N, M46I, L90LM L10F, N88D T12I, I13V, I15V, R57K, I62V, L63P, V77I, I93L  
CA3979 CA11780 IDV, SQV, NFV, RTV 149 I54IV, I84IV, L90M N88ND K20I, E35G, M36I, I62V, L63P, H69NT, A71X, I72V, T74TS  
  CA50876 IDV, SQV, NFV, RTV, LPV 397 M46I, I54V, I84V, L90M L10F I13IM, I15V, K20I, M36I, I62V, L63P, H69T, A71T, I72V, Q92QR  
CA4128 CA33490 IDV, NFV, SQV, RTV 266 D30N, I54IL, I84V, L90LM L10F, N88D I13V, K20T, L33V, I64V, A71V  
CA4293 CA23955 Unknown    I15V, L19Q, N37S, R57K, L63P  
CA5173 CA12752 NFV, SQV, RTV, IDV 126 D30N, M46L, I54V, L90M L33I, N88D I13V, E35D, M36I, R57K, L63P, A71AT, I93L  
CA6031 CA55107 NFV, SQV, RTV, APV 383 D30N, I54L, I84V, L90M L10F, L33F, N88D I13V, K45R, L63P, I93L  
CA6501 CA57789 NFV, LPV 334 D30DN, L90LM L33LF, N88ND I13V, I15IV, Q18I, L19I, D60E, L63P, V77VI, I93IL  
CA7073 CA17532 NFV 148 D30N, L90LM L10LF, N88D I13IV, L63P, A71AV, V77I, I93L  
CA7106 CA57607 NFV, RTV 246 D30N, M46I, I54L, L90M L33F, K43KT, N88D L19LI, I62V, L63P, I66L, A71T, I72IT, V77I, V82I, I93L  
CA8049 CA59208 IDV, NFV, SQV, RTV, ATV 354 D30N, I54V, L90M L33I, N88D I13V, E35D, M36I, N37T, I62V, L63P, A71T, T74S  
CA8464 CA21451 Unknown  D30DN, I47IV, I54L, L90LM L10F, L33F, N88D T12S, I13V, K20KT, L63P, A71AV, V77I, I93IL