<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author da Silva (2010)
Title HIV-1 resistance patterns to integrase inhibitors in antiretroviral-experienced patients with virological failure on raltegravir-containing regimens.
Citation J Antimicrob Chemother
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 21
NumPts 9
Subtype B, G


Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
1_J0 None    D3E, E10D, R20K, V32I, M50I, I72V, L101I, S119G, T122I, T125A, F181L, K211R, I220F  
  1_M9 RAL 39 E138EA, G140S, Q148H  E10D, R20K, V32I, L45LI, M50I, I72V, L101I, S119G, T122I, T125A, F181L, K211R, Q221S, N222K, V259VI  
11 11_J0 None   L74LM A23AV, P30PH, V31VIM, K34KR, I72V, V201I, K211Q  
  11_M12 RAL 52   A23V, I72V, V201I, K211Q  
2_M9 RAL 39 G140S, Q148H  D3DN, R20K, K160R, V201I  
3_J0 None    E10D, V31I, C56A, I60V, I72V, L74I, T124TA, I135IV, F181L, V201I, D256E Q285Q* 
  3_M9 RAL 39 G140S, Q148R  E10D, V31I, S39R, C56A, I60V, L63I, I72V, L74I, T124A, G134E, I135V, K156KN, K160KN, F181L, V201I, L234LV, D256E  
  3_M12 RAL 52 G140S, Q148R R263RK E10D, N18NK, V31I, S39R, Q53QK, C56A, I60V, L63I, I72V, L74I, T124A, G134E, I135V, K156N, F181L, V201I, L234V, D256E  
4_M0 None    K14R, V31I, Y99F, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218TS, Y227F, L234I, S255N, D256E S283G 
  4_M6 RAL 26 G140A, Q148R L74M K14R, N27NS, V31I, S39SR, V79VI, Y99F, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E S283G 
5_J0 None   V151VI E11D, E13D, V31I, M50I, S57G, S119P, T122I, T124A, T206S, S255N, D256E S283G 
  5_M1 RAL G140S, Q148H  E11D, E13D, V31I, M50I, S57G, I89V, S119P, T122I, T124A, T206S, S255N, D256E S283G 
6_J0 None    K7KR, S17N, V31I, K111T, I113V, T124Q, T125A, I203M  
  6_M1 RAL N155NH  S17N, V31I, K111T, I113V, T124Q, T125TA, I203M S283SR 
  6_M3 RAL 12 Y143C L74LM, Q95QK, V151VI, S230R K7KR, S17N, V31I, K111T, I113V, T124Q, T125A, A169AV, I203M T97TP, G189GV 
7_J0 None   V151VI S17SN, I72V, L101LI, G106GA, I113IV, S119SG, T122TI, T125TA, A169AS, I220IL, Y227YF, L234LV  
  7_M3 RAL 12 N155H  S17N, I72V, L101I, S119G, T122I, T125A, A169S, T218S, I220L, Y227F  
  7_M6 RAL 25 Y143YCHR T97TA, G163GR S17N, I72V, L101I, S119G, T122I, T125A, A169S, T218TS, I220L, Y227F  
  7_M9 RAL 39 Y143YCHR T97TA, G163GR S17N, I72V, L101I, G106GA, S119G, T122I, T125A, S195SN, A196AT, T218TS, I220L, Y227F A169FS, F185FL 
8_J0 None    E11D, V31VI, L101I, T122I, D232E, D256DE, A265V  
  8_M6 RAL 26 N155NH  E11D, V31VI, L101I, S119SG, T122I, D232E, D256DE, A265V