<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Underwood (2012)
Title The activity of the integrase inhibitor dolutegravir against HIV-1 variants isolated from raltegravir-treated adults.
Citation JAIDS
SelectedGene IN
SelectedSpecies HIV1
SelectedType Lab
NumIsolates 13
Lab Parent Strain NL43

Lab IN Isolates (including Susceptibility Data)

IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
SDM1 E92Q  PhenoSense RAL 5.0 
     PhenoSense SGSK1265744 1.5 
SDM10 G140S, Q148H  PhenoSense RAL >60 
     PhenoSense SGSK1265744 5.0 
SDM11 G140S, Q148R  PhenoSense RAL >60 
     PhenoSense SGSK1265744 4.0 
SDM12 E138K, Q148K  PhenoSense RAL >60 
     PhenoSense SGSK1265744 13 
SDM13 E138K, Q148R  PhenoSense RAL >60 
     PhenoSense SGSK1265744 5.0 
SDM2 Q148H  PhenoSense RAL 20 
     PhenoSense SGSK1265744 0.5 
SDM3 Q148K  PhenoSense RAL 50 
     PhenoSense SGSK1265744 3.0 
SDM4 Q148R  PhenoSense RAL 30 
     PhenoSense SGSK1265744 2.0 
SDM5  S153Y PhenoSense RAL 1.6 
     PhenoSense SGSK1265744 1.8 
SDM6 N155H  PhenoSense RAL 18 
     PhenoSense SGSK1265744 1.6 
SDM7 E92Q, N155H  PhenoSense RAL 50 
     PhenoSense SGSK1265744 2.0 
SDM8 Y143R T97A PhenoSense RAL >60 
      PhenoSense SGSK1265744 1.0 
SDM9 Y143C T97A PhenoSense RAL >60 
      PhenoSense SGSK1265744 1.2