<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Underwood (2012)
Title The activity of the integrase inhibitor dolutegravir against HIV-1 variants isolated from raltegravir-treated adults.
Citation JAIDS
SelectedGene IN
SelectedSpecies HIV1
SelectedType Lab
NumIsolates 13
Lab Parent Strain NL43

Lab IN Isolates (including Susceptibility Data)

IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
SDM1 E92Q V151I PhenoSense RAL 5.0 
      PhenoSense SGSK1265744 1.5 
SDM10 G140S, Q148H V151I PhenoSense RAL >60 
      PhenoSense SGSK1265744 5.0 
SDM11 G140S, Q148R V151I PhenoSense RAL >60 
      PhenoSense SGSK1265744 4.0 
SDM12 E138K, Q148K V151I PhenoSense RAL >60 
      PhenoSense SGSK1265744 13 
SDM13 E138K, Q148R V151I PhenoSense RAL >60 
      PhenoSense SGSK1265744 5.0 
SDM2 Q148H V151I PhenoSense RAL 20 
      PhenoSense SGSK1265744 0.5 
SDM3 Q148K V151I PhenoSense RAL 50 
      PhenoSense SGSK1265744 3.0 
SDM4 Q148R V151I PhenoSense RAL 30 
      PhenoSense SGSK1265744 2.0 
SDM5  V151I, S153Y PhenoSense RAL 1.6 
     PhenoSense SGSK1265744 1.8 
SDM6 N155H V151I PhenoSense RAL 18 
      PhenoSense SGSK1265744 1.6 
SDM7 E92Q, N155H V151I PhenoSense RAL 50 
      PhenoSense SGSK1265744 2.0 
SDM8 Y143R T97A, V151I PhenoSense RAL >60 
      PhenoSense SGSK1265744 1.0 
SDM9 Y143C T97A, V151I PhenoSense RAL >60 
      PhenoSense SGSK1265744 1.2