<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Underwood (2012)
Title The activity of the integrase inhibitor dolutegravir against HIV-1 variants isolated from raltegravir-treated adults.
Citation JAIDS
SelectedGene IN
SelectedSpecies HIV1
SelectedType Lab
NumIsolates 13
Lab Parent Strain NL43

Lab IN Isolates (including Susceptibility Data)

IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
SDM1 E92Q  PhenoSense DTG 1.5 
     PhenoSense RAL 5.0 
SDM10 G140S, Q148H  PhenoSense DTG 5.0 
     PhenoSense RAL >60 
SDM11 G140S, Q148R  PhenoSense DTG 4.0 
     PhenoSense RAL >60 
SDM12 E138K, Q148K  PhenoSense DTG 13 
     PhenoSense RAL >60 
SDM13 E138K, Q148R  PhenoSense DTG 5.0 
     PhenoSense RAL >60 
SDM2 Q148H  PhenoSense DTG 0.5 
     PhenoSense RAL 20 
SDM3 Q148K  PhenoSense DTG 3.0 
     PhenoSense RAL 50 
SDM4 Q148R  PhenoSense DTG 2.0 
     PhenoSense RAL 30 
SDM5  S153Y PhenoSense DTG 1.8 
     PhenoSense RAL 1.6 
SDM6 N155H  PhenoSense DTG 1.6 
     PhenoSense RAL 18 
SDM7 E92Q, N155H  PhenoSense DTG 2.0 
     PhenoSense RAL 50 
SDM8 Y143R T97A PhenoSense DTG 1.0 
      PhenoSense RAL >60 
SDM9 Y143C T97A PhenoSense DTG 1.2 
      PhenoSense RAL >60