Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Underwood (2012)
Title The activity of the integrase inhibitor dolutegravir against HIV-1 variants isolated from raltegravir-treated adults.
Citation JAIDS
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 11
Lab Parent Strain NL43


Lab IN Isolates : Susceptibility Data

IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
138K+148K E138K, Q148K  PhenoSense DTG 7.0 
     PhenoSense RAL >81 
138K+148R E138K, Q148R  PhenoSense DTG 2.1 
     PhenoSense RAL 75 
140S+148H G140S, Q148H  PhenoSense DTG 4.1 
     PhenoSense RAL >87 
140S+148R G140S, Q148R  PhenoSense DTG 4.0 
     PhenoSense RAL >87 
148H Q148H  PhenoSense DTG 0.5 
     PhenoSense RAL 20 
148K Q148K  PhenoSense DTG 0.8 
     PhenoSense RAL 53 
148R Q148R  PhenoSense DTG 0.8 
     PhenoSense RAL 32 
153Y  S153Y PhenoSense DTG 2.5 
     PhenoSense RAL 2.0 
155H N155H  PhenoSense DTG 1.8 
     PhenoSense RAL 17 
92Q E92Q  PhenoSense DTG 2.0 
     PhenoSense RAL 6.0 
92Q+155H E92Q, N155H  PhenoSense DTG 2.4 
     PhenoSense RAL 80