<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Underwood (2012)
Title The activity of the integrase inhibitor dolutegravir against HIV-1 variants isolated from raltegravir-treated adults.
Citation JAIDS
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 21
NumPts 7
Subtype B


Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
Virus88 None    S17N, S24D, S39C, L45LQ, L101I, T124N, D167E, V201I, E212EA R284RG, D286N 
  Virus4 RAL  G140S, Q148H  S17N, S24D, S39C, L45LQ, L101I, T124N, D167E, V201I, E212A R284G, D286N 
  Virus5 RAL  G140S, Q148H  S17N, S24D, S39C, L45LQ, L101I, T124N, D167E, V201I, E212A R284G, D286N 
12 Virus101 RAL  Y143YC T97A, S230R G4GR, R20K, T112V, I113V, T125A, H171Q, Y194YH, I200M, I203M  
  Virus122 RAL  Y143YC T97TA, S230SR R20K, T112V, I113V, T125A, H171Q, I200M, I203IM  
  Virus139 RAL  Y143YC L74LM, T97TA, S230SR R20K, T112V, I113V, S119ST, T125A, H171Q, I200M, I203IM, T218TS  
14 Virus14 RAL    D6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, M275V  
Virus96 None    D6E, E10D, V31I, L101I, T124A, K156N, V201I, V249VI, M275V  
  Virus9 RAL  N155H V151I D6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275V  
  Virus12 RAL  N155H V151I D6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275V  
Virus25 None    S17N, I72V, L101LI, K156N, V201I, I208L, R228RK D286DN 
  Virus27 RAL  G140S, Q148H  S17N, I72V, L101I, K156N, V201I, D207DG, I208L  
  Virus28 RAL  E138EK, G140GS, Q148QH  S17N, I72V, L101LI, K156N, V201I, I208L D286DN 
Virus30 RAL  G140GS, Q148QH  S17N, I72V, A98AT, L101I, K156KN, V201I, I208L D286DN 
  Virus32 RAL  E138EK, G140GS, Q148QH N155ND S17N, I72V, L101LI, K156KN, V201I, I208L, D256DE D286DN 
  Virus34 RAL  E138EA, G140GS, Q148QH  S17N, I72IV, L101I, K156KN, V201I, I208L  
  Virus37 RAL  E138EA, G140GS, Q148QH  S17N, I72IV, L101LI, K156KN, E170EK, V201VI, I208IL, V259VA Q62Q* 
  Virus38 RAL  E138EA, G140GS, Q148QH  S17N, I72IV, L101I, K156KN, V201I, I208L Y83YC 
Virus42 None    S17N, V31I, V79VI, L101I, I113IL, T124A, K211KR, L234I, A265AV  
  Virus46 RAL  E92EQ, G140GS, Q148QR, N155NH  S17N, V31I, V79VI, L101I, T124A, L234I  
  Virus49 RAL  E92EQ, Y143R T97TA S17N, V31I, L101I, T124A, A169AG, L234I