<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Knops (2010)
Title Evolution of protease inhibitor resistance in the gag and pol genes of HIV subtype G isolates.
Citation J Antimicrob Chemother
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 21
NumPts 21
Subtype G


Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
Pat02 Pat02 D4T, 3TC None M184V  K20R, V35R, V60I, K102Q, K104KR, K122E, D123S, I135T, Q174K, D177E, I178M, T200A, Q207E, R211K, F214L, K238KR, V245Q, E248D, D250E, A272P, V276I, L283I, V292I, I293V, E297A, V317A, D324E, I329V E6*KQ, E203EGKR 
Pat03 Pat03 None None   V35T, V60I, K104R, K122E, D123S, K166R, Q174GR, D177E, I178M, T200A, Q207E, R211RK, V245Q, E248D, D250E, A272P, V276I, L283I, T286S, V292I, I293V, E297EK E302A 
Pat04 Pat04 D4T, 3TC None M184V  V35I, V60I, K102Q, K104R, K122E, D123N, I135L, I142V, K173R, Q174K, P176S, D177E, I178M, T200A, Q207E, V245Q, E248D, D250E, A272P, L283LI, V292I, I293V, E297EK P119PL, E302A 
Pat05 Pat05 DDI EFV D67N, K70R, L74I, T215F, K219Q K101P, K103N I2IV, V60I, T69N, V90I, I94IL, K102Q, V106VI, K122E, D123S, I135T, S162Y, K173S, Q174K, D177E, I178IL, I195L, T200A, E203ED, Q207E, R211K, V245Q, E248D, D250E, A272P, V276I, L283I, A288AT, V292VI, I293V, E297A, V317A, D324E, I329IV  
Pat06 Pat06 DDI NVP L74V, T215F K103N V35I, K64R, A98S, K102Q, K122E, D123NS, I135L, K173R, Q174K, I178M, T200A, R211K, V245Q, E248D, D250E, A272P, L283I, E291D, V292I, I293V, V317A, S322A, D324E, I329V  
Pat07 Pat07 D4T, 3TC EFV M41L, D67DG, M184V, T215F V179E V21I, V35T, V60VI, S68SG, K104R, K122E, D123S, I135T, I142V, Q174K, D177E, I178M, T200A, Q207A, R211K, V245Q, E248D, D250E, A272P, V276I, I293V, E297A, V317A, P321S, D324E, I329V, Q332H L283IT 
Pat08 Pat08 AZT, 3TC, D4T, DDI EFV M41L, D67N, K70R, L74LI, T215F, K219EQ K101E, V108I, Y181C, G190A, Y318F K20R, V35I, T39A, K49KR, V60I, K102Q, V118VI, K122E, D123N, I135K, S162D, K173R, I178M, T200A, E204EQ, Q207DE, R211K, D218E, L228H, V245Q, E248ED, D250E, S251G, A272P, L283I, V292I, I293V, E297A, V317A, I329IV  
Pat09 Pat09 3TC, D4T, DDI EFV M41L, T215F K103N, Y188L L34I, V35T, K102Q, V118I, K122E, D123S, G141A, K166R, K173R, D177E, I178M, T200A, Q207E, R211K, F214L, V245Q, E248D, D250E, A272P, V276I, L283I, E291D, I293V, E297EK E302A 
Pat10 Pat10 3TC, D4T, DDI NVP M184MIV, K219KE Y181YC V21VI, V35VAIT, K49R, I50IV, V60VI, K102Q, K104R, K122E, D123S, I135IM, K173T, Q174K, D177E, I178M, I195IL, T200A, E203EG, Q207E, R211K, D218DE, D237DN, V245Q, E248D, D250E, A272P, V276I, L283I, V292VI, I293V, P294PA, E297A, V317A, D324E, I329V S48I 
Pat11 Pat11 3TC EFV M184V, K219KQ Y181YC, P225PH V21I, V35T, K49R, V60I, K102Q, K104R, K122E, D123G, K166R, K173T, Q174R, D177E, I178M, T200A, Q207E, R211K, H221HY, V245Q, E248D, D250E, A272P, V276VA, K277R, L283I, I293V, E297A, V317A, D324E, I329V  
Pat12 Pat12 AZT, 3TC None D67N, K70R, M184V, K219Q  V35T, V60I, R83RK, K104R, K122E, D123S, K173R, Q174R, D177E, I178M, T200A, Q207E, R211K, F214L, K238R, V245Q, E248D, D250E, A272P, V276I, K277R, L283I, T286A, V292I, I293V, E297A, V317A, D324E, I329V  
Pat13 Pat13 DDI, AZT, 3TC None D67N, T215L, K219Q K103N K32I, V35R, V60I, T69N, K102Q, K104R, K122E, D123S, I135T, I142IT, S162C, Q174N, D177E, I178M, I195L, T200A, I202V, Q207D, R211K, V245Q, E248D, D250E, S251SN, A272P, L283I, I293V, P294T, E297A, V317A, D324E, I329V  
Pat14 Pat14 3TC, DDI NVP, EFV M41L, D67N, L74LV, L210W, T215Y, K219KE K101E, Y181C, G190A V35T, T39TA, V60I, K102Q, K104KR, V118VI, K122E, D123S, I135T, K173N, Q174K, D177E, I178M, I195IM, T200A, E203EK, Q207D, R211K, D218DE, V245Q, E248D, D250E, A272P, L283I, V292I, I293IV, E297A, D324E, I329V P1PA, E138T, S191SCW 
Pat15 Pat15 AZT, 3TC NVP M41L, D67DN, L210LRW, T215Y A98AG, Y181YC K20KR, V35T, V60I, K102Q, K104KR, V118VI, K122E, D123S, I135V, K173T, Q174K, D177E, I178M, G196GE, T200A, Q207E, R211K, T240TK, V245Q, E248D, D250E, A272P, V276VI, L283I, R284K, K287KR, E291D, V292I, I293V, E297A, V317A, D324E, I329IV  
Pat16 Pat16 AZT, 3TC EFV M41ML, T215TADN  V35T, V60I, T69TS, K102Q, K104KR, K122E, D123S, I135V, K173T, Q174N, D177E, I178IM, T200A, Q207E, R211K, V245Q, E248D, D250DE, A272P, V276I, L283I, R284RK, T286TN, V292VI, I293V, E297A, V317A, D324E  
Pat17 Pat17 DDI EFV, NVP M41L, D67N, T215C, K219Q K103N, V108I, V179E K32I, V35R, T39A, V60I, T69N, K102Q, K122E, D123S, I132L, K173R, Q174K, D177E, I178M, E194EA, I195L, G196E, Q197I, T200A, E203D, Q207E, L228H, V245Q, E248D, D250E, A272P, L283I, T286P, E291D, V292I, I293V, E297EK E302A 
Pat18 Pat18 3TC None K219Q  V35T, V60I, T69S, K122E, D123S, I135T, K173T, Q174N, D177E, I178M, T200E, E203K, Q207E, R211K, V245Q, E248D, D250E, A272P, V276I, L283I, E291D, V292I, I293V, E297A, D324E, I329V  
Pat19 Pat19 3TC, DDI EFV M41L, D67N, K70R, V75M, M184V, T215F, K219Q Y181C, G190A P4Q, K20R, V21I, V35I, T39A, V60I, K101KQ, K102Q, D121H, K122E, D123S, K166R, Q174R, D177E, I178M, T200A, Q207E, H208Y, R211K, D218E, L228H, V245Q, E248D, D250E, A272P, L283I, T286A, E291D, V292I, I293V, E297AT, R307RK, I329V V179Q 
Pat20 Pat20 None EFV  K103N V21D, V35I, V60I, K122E, D123S, I135T, K173R, Q174K, I178M, G196E, T200A, Q207E, R211K, V245Q, E248D, A272P, K275R, V276I, L283I, E291D, V292I, I293V, E297A, V317A, D324E, I329V K22Q 
Pat21 Pat21 D4T, DDI, 3TC NVP M41L, M184V, T215Y A98AG V35T, K43KQ, K49KR, V60I, S68SG, K102Q, K104R, K122E, D123S, I135T, K173R, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q, E248D, D250E, A272P, V276I, L283I, T286A, E291D, I293V, E297EK  
Pat22 Pat22 AZT None   K11KT, V21I, V35I, V60I, K102Q, K122E, D123S, Q174R, D177E, I178M, I195L, T200A, Q207E, R211RK, V245Q, E248D, D250E, A272P, K275R, V276I, K277R, L283I, T286A, E291D, V292I, I293V, E297EK E302A