<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Hatano (2010)
Title Evolution of integrase resistance during failure of integrase inhibitor-based antiretroviral therapy.
Citation JAIDS
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 134
NumPts 56
Subtype B


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Page 1   from Isolate 1 to Isolate 100 from Total 134 Clinical IN Isolates

SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
Virus88 None    S17N, S24D, S39C, L45LQ, L101I, T124N, D167E, V201I, E212EA R284RG, D286N 
  Virus3 RAL    S17N, S24D, S39C, L101I, T124N, D167E, V201I, E212EA R284RG, D286N 
  Virus4 RAL  G140S, Q148H  S17N, S24D, S39C, L45LQ, L101I, T124N, D167E, V201I, E212A R284G, D286N 
  Virus5 RAL  G140S, Q148H  S17N, S24D, S39C, L45LQ, L101I, T124N, D167E, V201I, E212A R284G, D286N 
15 Virus17 None    K7KR, S17N, V31I, L101I, T112V, G193D, V201I, T218S, D256E  
  Virus76 EVG  E92EQ  K7KR, S17N, V31I, L101I, T112V, G193D, V201I, T218S, D256E, D279DG  
  Virus79 EVG  E92EQ Q146QL K7KR, S17N, V31I, I84IM, L101I, T112V, I135IV, G193D, V201I, T218S, D256E, D279DG  
16 Virus105 None    R20K, I72IV, T112A, T124A  
  Virus21 EVG  E92Q  R20K, T112A, T124A, T125TM  
  Virus22 EVG  E92EQ  R20K, T112A, T124A  
17 Virus99 EVG  E138K, S147G, Q148R  K7KR, I72V, V79VI, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234I  
  Virus100 EVG  E138K, S147G, Q148R V54VI K7KR, I72V, V79I, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234I  
  Virus103 EVG  E138K, S147G, Q148R V54VI K7KR, E35EQ, I72IV, V79I, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234I  
  Virus20 EVG  E138K, S147G, Q148R V54I K7KR, E35EK, I72V, V79I, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234I  
18 Virus89 None    K7KR, G59GE, I72V, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234I  
  Virus19 EVG    K7R, I72V, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, L234I  
  Virus91 EVG    K7R, I72V, V88I, K111Q, I113V, T124A, T125A, G163E, I203IM, I208L, L234I  
  Virus94 EVG  E92Q  K7KR, D41DN, I72V, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, E212EA, L234I  
  Virus95 EVG  E92Q, Q148QR L74LM K7KR, D41DN, I72IV, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, E212EA, L234I  
  Virus97 EVG  E92Q L68LV, L74LM K7KR, D41DN, I72IV, V88I, K111Q, I113V, T124A, T125A, G163E, I203M, I208L, E212EA, L234I  
Virus93 None    L63I, I73V, L74I, E96D, L101I, T112IV, I208L, D232E  
  Virus114 RAL  G140S, Q148H  L63I, I73V, L74I, E96D, L101I, T112I, I208L, D232E, L234LF  
  Virus8 RAL  G140S, Q148H  L63I, I73V, L74I, E96D, L101I, T112I, I208L, D232E  
21 Virus61 Unknown    V31I, I72V, L74I, I89L, G106A, T112I, I113V, T125A, V176L, T206S, D207E, I208L, T218I  
  Virus6 Unknown   L74M, V151I V31I, I72V, I89IL, G106GA, T112I, I113V, T124N, T125A, I135IV, V176VL, T206S, D207E  
  Virus130 Unknown   L74IM, V151VI V31I, I72V, I89IL, G106GA, T112TI, I113V, S119ST, T124N, T125A, I135IV, V176VL, T206S, D207E  
  Virus135 Unknown   L74IM, V151VI V31I, I72V, I89IL, G106GA, T112TI, I113V, S119ST, T124N, T125A, I135IV, V176VL, T206S, D207E L101LF 
22 Virus71 Unknown    D6E, L28M, V31VI, V32VI, L101I, T112A, T125A, K160KT, I203M, I208L, L234I  
  Virus7 Unknown   V54I D6E, L28M, V31I, V32I, L101I, T112A, T125A, K160R, V201I, I208L, L234I  
24 Virus29 Unknown    E11D, A21T, A23V, S39C, S119P, V201I, I203IM  
  Virus31 Unknown    E11D, A21T, A23V, S39C, S119P, V201I, I203IM  
  Virus45 Unknown    E11D, V31I, V37I, I72IV, L101I, T112V, T124TA, K173R, V201I, T206S, D256E R284G 
  Virus48 Unknown    E11D, V31I, V37I, L101I, T112V, T124TA, K173R, V201I, T206S, D256E R284G 
  Virus50 Unknown    E11D, V31I, V37I, I72IV, L101I, T112V, T124TA, K173R, V201I, T206S, D256E R284G 
  Virus55 Unknown    E11D, V31I, V37I, I72V, L101I, T112V, T124A, K173R, V201I, T206S, D256E R284G 
  Virus57 Unknown    E11D, V31I, V37I, I72IV, L101I, T112V, T124A, K173R, V201I, T206S, D256E, C280CS R284RG 
  Virus115 Unknown    E11D, V31I, V37I, I72IV, L101I, T112V, T124TA, K173R, V201I, T206S, D256E R284G 
25 Virus54 Unknown    K7R, S17N, V31I, M50I, I72V, L101I, T124A, T125TA, I135V, I203IM, K211Q, T218I, D232E, D256E, A265AV  
  Virus58 Unknown    K7R, S17N, V31I, M50I, I72V, L101I, T124A, T125A, I135V, K211Q, T218I, D232E, D256E  
  Virus60 Unknown    K7R, S17N, V31I, M50I, I72V, L101I, T124A, T125A, I135V, I203M, K211Q, T218I, D232E, D256E, A265V  
  Virus63 Unknown    K7R, S17N, V31I, M50IT, I72IV, L101I, T124A, T125A, I135V, I203IM, K211Q, T218I, D232E, D256E  
26 Virus73 Unknown    K7KR, E11D, V31I, V37I, I72V, K111T, T112V, I113V, S119P, T124N, T125A, I135V, V165I, V201I, D256E  
  Virus75 Unknown    E11D, V31I, V37I, I72V, K111T, T112V, I113V, S119P, T124N, T125A, I135V, V165I, V201I, D256E  
  Virus66 Unknown    E11D, V31I, V37I, M50MI, L101I, K156N, V201I, D256E  
  Virus119 Unknown    E11D, V31I, V37I, M50MI, L101I, K156N, V201I, L234LF, D256E  
27 Virus53 Unknown    V31VI, L101I, T112TI, I135IV, F181L, V201I, T206S, D256E, I268L, D270H R284G 
  Virus56 Unknown    V31VI, P90PS, L101I, T112TI, I135IV, F181L, V201I, T206S, D256E, I268L, D270H R284G 
  Virus59 Unknown    V31VI, L101I, T112TI, I135IV, F181L, V201I, T206S, I217IV, D256E, I268L, D270H R284G 
  Virus62 Unknown    V31VI, L101I, T112TI, I135IV, F181L, V201I, T206S, D256E, I268L, D270H R284G 
  Virus64 Unknown    V31VI, L101I, T112TI, I135IV, F181L, V201I, T206S, D256E, I268L, D270H R284G 
28 Virus70 Unknown    D6E, S17N, E35Q, S39N, L45V, M50I, L101I, K136Q, D167E, K211R, K215N, D256E  
  Virus72 Unknown    D6E, S17N, E35Q, S39N, L45V, M50I, L101I, K136Q, D167E, T174TA, K211R, K215N, D256E A276AT 
  Virus138 Unknown   V151VI D6E, E13EG, S17N, E35Q, S39N, L45V, M50I, L101I, K136Q, D167E, K211R, K215N, D256E  
29 Virus67 Unknown    S17N, M50MI, I72V, T112TI, I113V, S119P, T124A, V201VI, T206S, I208IL, E212EA, D256E S283SG, R284G, D286N 
  Virus1 Unknown    S17N, M50I, I72V, T112TI, I113IV, S119P, T124A, V201VI, T206S, I208IL, E212EA, D256E S283SG, R284G, D286N 
  Virus2 Unknown    S17N, V31VI, M50MI, I72V, I113V, S119P, T124A, V201VI, T206S, I208IL, E212EA, D256E S283SG, R284G, D286N 
  Virus118 Unknown   E138Q S17N, I72V, L101I, T112V, S119T, T124S, K156N, I208L, E212L, I220L, Y227F, D256E, A265V, D279G R284G 
  Virus121 Unknown   E138Q S17N, I72V, L101I, T112V, S119T, T124S, G134GE, K156N, I208L, E212L, I220L, Y227F, D256E, A265V, D279G R284G 
  Virus125 Unknown    S17N, V31VI, M50MI, I72V, I113IV, S119P, T124A, V201VI, T206S, I208IL, K211KQ, D256E E212EAPQ, S283SG, R284G, D286N 
  Virus133 Unknown   E138Q S17N, I72V, L101I, T112V, S119T, T124S, K156N, I208L, E212L, I220L, Y227F, D256E, A265V, D279G R284G 
  Virus132 Unknown    S17N, M50MI, I72V, I113IV, S119P, T124A, L172LF, V201VI, T206S, I208IL, E212EA, R231RK, D256E K159KR, A239AV, R284G, D286N 
Virus96 None    D6E, E10D, V31I, L101I, T124A, K156N, V201I, V249VI, M275V  
  Virus9 RAL  N155H V151I D6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275V  
  Virus10 RAL  N155H V151I D6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275V  
  Virus11 RAL  N155H V151I D6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275V  
  Virus12 RAL  N155H V151I D6E, E10D, A23S, V31I, L101I, T124A, K156N, V201I, D232N, M275V  
30 Virus74 Unknown    E11D, S39SI, S57SN, L101LI, I113V, S119P, T122TAIV, T125A, F181L, V201I, I203IM, I220L, Y227F, L234I  
38 Virus40 Unknown    E11D, S17T, A23V, N27G, L101I, K111KT, S119X, T122TI, T206TS, T218TS, D253E, D256E, V259I  
Virus15 RAL  Y143R T97A K7R, S17N, V31I, L101I, T112A, T125A, M154I, V201I  
  Virus16 RAL  Y143R T97A, G163GR K7R, S17N, V31I, L101I, T112A, S119T, T125A, M154I, V201VI  
40 Virus33 Unknown    S17N, L101I, K111AT, S119P, T125A, I135IV, Q216QH, D232DE, D256DE  
41 Virus35 Unknown    S17N, L101I, T112I, T124S, T125V, G163E  
42 Virus51 Unknown    S17N, D25E, V31I, L101I, G106A, T122I, T124N, K156N, L172LF, I182V, D256E P58PL 
43 Virus69 Unknown    S17N, I72V, K111Q, I113V, T124A, T125A, S255SG  
44 Virus43 Unknown   E138Q S17N, M50I, I72V, L101I, T112V, S119T, T124S, K156N, I208L, E212L, I220L, Y227F, D256E, A265V R284G, D288N 
49 Virus41 Unknown    V31I, M50I, S119P, V165VI, R231K V281VM 
Virus25 None    S17N, I72V, L101LI, K156N, V201I, I208L, R228RK D286DN 
  Virus27 RAL  G140S, Q148H  S17N, I72V, L101I, K156N, V201I, D207DG, I208L  
  Virus28 RAL  E138EK, G140GS, Q148QH  S17N, I72V, L101LI, K156N, V201I, I208L D286DN 
51 Virus47 Unknown    E13ED, S17SN, V31I, L45LV, L101I, S119G, T122V, I208L  
52 Virus36 Unknown    I72V, S230N, L234I, A265AV I268IFL 
53 Virus39 Unknown    I72IV, L101LI, T112TI, I113IV, T124TA, I208IL, S230SN  
54 Virus68 Unknown   V151I D25DE, L28LI, V31VI, I72V, T112TR, V165VI, K211KR, K215N, I220IL D286DN 
56 Virus52 Unknown   V151I D6N, K7E, R20RK, D41N, L101I, S119T, T125A, I208L, E212A, D229E  
57 Virus44 Unknown   V151I E11D, I72V, T112R, K156N, R187K, V201I, T218S  
58 Virus26 Unknown    E10D, E11ED, E13ED, S17ST, A23AV, S24SN, L101I, K103KR, T112V, S119P, T122I, T124A, K136KR, V201VI, D256E  
Virus23 RAL  T66TA, N155NH H51HY L101I, T112I, V201VI, K211Q, I217V, K240KR K266KR 
  Virus24 RAL  E92EQ, G140GS, Q148QK, N155NH H51HY, G163GR L101I, T112I, I162IV, V201VI, K211Q, I217V T124TADN 
Virus65 None   V151I D25E, I72V, K211R, K215N  
  Virus120 RAL   V151I D25E, I72V, H78HR, K211R, K215N, L234LF  
  Virus129 RAL  G140S, Q148H V151I D25E, I72V, K211R, K215N  
Virus30 RAL  G140GS, Q148QH  S17N, I72V, A98AT, L101I, K156KN, V201I, I208L D286DN 
  Virus32 RAL  E138EK, G140GS, Q148QH N155ND S17N, I72V, L101LI, K156KN, V201I, I208L, D256DE D286DN 
  Virus34 RAL  E138EA, G140GS, Q148QH  S17N, I72IV, L101I, K156KN, V201I, I208L  
  Virus37 RAL  E138EA, G140GS, Q148QH  S17N, I72IV, L101LI, K156KN, E170EK, V201VI, I208IL, V259VA Q62Q* 
  Virus38 RAL  E138EA, G140GS, Q148QH  S17N, I72IV, L101I, K156KN, V201I, I208L Y83YC 
Virus42 None    S17N, V31I, V79VI, L101I, I113IL, T124A, K211KR, L234I, A265AV  
  Virus46 RAL  E92EQ, G140GS, Q148QR, N155NH  S17N, V31I, V79VI, L101I, T124A, L234I  
  Virus49 RAL  E92EQ, Y143R T97TA S17N, V31I, L101I, T124A, A169AG, L234I  
  Virus131 RAL  Y143YCHR L74LM, T97TA S17N, V31I, I60IM, G70GE, V79VI, L101I, S119ST, T124A, L234I G47GE