Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Deshpande (2010)
Title Analysis of RT sequences of subtype C HIV-type 1 isolates from Indian patients at failure of a first-line treatment according to clinical and/or immunological WHO guidelines.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 27
NumPts 27
Subtype C


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
12IND425 12IND425 D4T, 3TC NVP A62V, D67G, T69D, K70R, V75I, F77L, Q151M, M184I K103N, Y181C K20R, V35T, T39D, S48T, V90I, D121H, K122E, S162Y, K173A, Q174K, D177E, I178L, V179I, G196K, T200A, Q207E, R211K, H221Y, V245Q K32G 
14IND426 14IND426 D4T, 3TC EFV T69~, V75T, Q151M, M184V Y188L V35T, T39N, S48T, V60I, S68G, D121Y, K122E, D123E, I142V, K173A, D177E, V179I, V189I, T200A, I202V, Q207G, R211K, F214L, L228Q, V245Q I37M 
15IND427 15IND427 D4T, 3TC EFV  K103N V35T, T39N, S48T, V60I, D121Y, K122E, I135IT, A158S, S162A, T165I, K173T, D177E, T200A, Q207E, R211K, L228LR, V245E  
16IND428 16IND428 D4T, 3TC NVP D67N, K70R, M184V, T215F, K219E Y181C V35T, T39D, S48T, V60I, V90I, D121Y, K122E, D123G, I135R, S162A, T165L, K173T, Q174K, D177E, I178L, T200A, I202V, Q207E, R211K, V245Q  
22IND429 22IND429 D4T, 3TC NVP M41L, D67N, M184V, L210W, T215Y A98AG, K101E, V106VAMT, V108I, Y181IS, G190A K20R, V35T, T39D, E44D, K49R, V60I, I94L, V118I, K122E, D123S, I135T, S162A, T165L, K173A, D177E, V179I, V189VI, T200A, E203D, Q207E, R211K, H221Y, V245Q  
23IND43 23IND43 AZT, 3TC NVP M41L, D67N, K70R, M184V, T215Y, K219E Y188L E28K, K32E, V35T, E36A, T39E, S48T, V60I, I94L, K122E, D123N, K173T, D177E, V189I, T200A, Q207E, H208Y, L228H, V245Q  
26IND431 26IND431 None None K65R, T69~, K219R K103N, Y181C L34I, V35T, T39E, S48T, S68G, D121Y, K122E, I135T, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, H221Y, V241G, V245Q P140T 
31IND432 31IND432 None None A62V, K65R, V75T, Q151M, M184V V108I, Y181C K20R, V35T, T39E, S48T, S68G, K122DE, I135T, K166R, K173A, Q174R, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q  
32IND433 32IND433 D4T, 3TC NVP D67N, K70R, F116Y, Q151QKLM, M184V, K219Q K103N V35T, T39E, S48T, V60I, S105SL, K122E, D123NS, I135T, E169EA, K173A, D177E, I178IM, T200A, I202IV, Q207AP, L210LS, R211K, D218E, V245Q V111VIM 
33IND434 33IND434 D4T, 3TC NVP M41ML, D67DN, K70KR, M184V, T215TNSY, K219Q A98AG, K101KPQT, K103N, P225PH E28EA, V35T, E36EAD, T39DE, S48ST, V60I, D121Y, K122E, S162A, K173AT, Q174K, D177E, G196GE, T200A, E203EV, Q207D, R211K, L228LH, V245Q I135ILPT 
34IND435 34IND435 AZT, 3TC NVP M41L, D67N, T69D, K70R, L74I, M184V, T215F, K219W K103N, V108VI, Y181C V35T, E36A, T39D, V60I, D121Y, K122E, D123E, I135T, E138Q, S162A, K173A, D177EG, T200A, Q207E, R211K, L228H, V245K  
35IND436 35IND436 D4T, 3TC NVP, EFV M41ML, M184V, T215F, K219K*RW K101P, G190A V35IT, T39E, S48T, V60I, K102Q, D121Y, K122E, I135T, K166R, K173T, T200A, Q207D, R211K, F214L, L228LH, V245Q  
36IND437 36IND437 AZT, 3TC EFV, NVP M41L, D67N, K70R, M184V, T215F, K219Q K101E, V106M, G190A E28K, K32E, V35T, E36A, T39D, S48T, V60I, V90I, I94L, D121Y, K122E, S162A, K173AT, D177E, V179VI, T200E, Q207R, R211DE, V245Q  
37IND438 37IND438 D4T, 3TC, AZT NVP M41L, D67N, K70R, V75M, M184V, T215Y G190A K20KR, V35T, T39D, S48T, V60I, T69S, K102Q, D121Y, K122E, T139R, S162AT, K173T, D177E, I178M, V179I, T200A, Q207E, R211K, V245Q  
38IND439 38IND439 AZT, 3TC NVP M41L, D67N, V75M, M184V, L210L*W, T215Y K103N, K238T V35T, T39N, V60I, V90I, I94L, D121Y, K122E, I135T, S162A, K173T, D177E, T200A, Q207E, F214FL, V245Q, D256E  
39IND44 39IND44 D4T, 3TC NVP M41L, D67N, V75M, M184V, L210W, T215Y K103N, K238T V35T, T39N, V60I, V90I, I94L, D121Y, K122E, I135T, S162A, K173T, D177E, T200A, Q207E, V245Q L34LS, W239WC 
41IND442 41IND442 D4T, 3TC NVP M41L, L74V, M184V, T215Y K103N, V108I, Y181V K20R, V35T, T39N, S48T, V60I, L109I, K122E, D123N, I135T, K173T, D177E, T200A, I202V, Q207E, R211K, H221Y, V245K W24WG 
45IND443 45IND443 None None M41L, D67N, K70R, L74V, M184V, L210W, T215Y, K219E K103N, V108I, Y181C K20R, V35T, T39E, E44D, V60I, V118I, D121Y, K122E, I135V, S162A, K173T, D177E, T200A, E203D, Q207E, R211K, D218E, L228H, V245Q  
4IND441 4IND441 None None M41L, D67N, K70R, V75I, F77L, M184V, T215Y Y181C, G190A M16V, V35T, T39E, S48T, T58S, V60I, V118I, D121Y, K122E, I135R, K173A, Q174R, D177E, I178M, T200A, Q207G, H208Y, L210LS, R211K, W212M, H221Y, V245Q  
55IND445 55IND445 D4T, 3TC NVP M184V Y181C V35T, T39D, S48T, V90I, K102Q, K122E, I135M, S162Y, K166R, K173A, D177E, I178L, V179I, T200A, Q207E, L228R, V245Q L187LW 
56IND446 56IND446 D4T, 3TC NVP K65R, T69~, K219R V106M, Y181C L34I, V35T, T39E, S48T, S68G, D121H, K122E, I135T, S162C, K173A, D177E, I195IM, T200A, I202V, Q207E, F214L, K223Q, V245Q P157A 
57IND447 57IND447 None None D67N, K70KR, F116Y, Q151M, M184V, K219E K103N, V106M, F227FL K20R, V35T, E36A, T39D, S48T, V60I, K82R, I94L, K122E, D123S, I135V, K173T, D177E, T200A, I202V, Q207K, R211A, F214FL, V245Q  
5IND444 5IND444 None None M41L, D67N, V75M, M184V, L210W, T215Y Y188L V35T, T39D, E44D, S48T, V60I, V118I, I135T, S162D, K166R, E169A, K173A, D177E, T200A, E203K, Q207A, H208Y, R211K, K223E, V245Q  
65IND448 65IND448 D4T, 3TC NVP M41L, V75M, M184V, T215F, K219W K103N, V108I, Y181C V8I, T27S, V35T, T39D, S48T, V60I, V90I, K122E, I135R, S162F, K173A, Q174K, D177E, T200A, Q207E, D218E, L228R, V245Q  
66IND449 66IND449 D4T, 3TC NVP D67N, M184V, T215F, K219W K101E, Y181C, G190A V35T, T39E, S48T, V60I, V118I, D121H, K122E, I135R, T139K, S162D, K173T, V179I, T200A, Q207E, H208Y, R211K, K223E, V245Q, D250E  
67IND45 67IND45 AZT, 3TC NVP M41ML, D67DN, M184MV, T215TN Y188L V35M, T39E, E44ED, S48T, V60I, R172RK, K173T, Q174K, D177E, I178LM, T200A, E203ED, Q207AEKT, H208HY, R211K, H221HY, K223KE, V245Q  
68IND451 68IND451 AZT, 3TC NVP M41L, D67N, K70R, L74I, M184V, T215F, K219Q A98G, K103N, K238T V35T, T39D, S48ST, V60I, K122E, D123N, I135L, E138A, I142V, S162SN, Q174K, N175Y, T200E, Q207A, R211K, L228LH, V245Q L168LV