Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Nouhin (2011)
Title Natural polymorphisms of HIV-1 CRF01_AE integrase coding region in ARV-naive individuals in Cambodia, Thailand and Vietnam: an ANRS AC12 working group study.
Citation Infect Genet Evol.
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 50
NumPts 49
Subtype CRF01_AE

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
107 VNR107 None    K14R, W19R, A21T, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, R187K, V201I, L234I, S283G, D286N  
109295 KCT0109295 None    K14R, A21T, A23V, S39N, D55G, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I C56G 
1126367 KCS1126367 None    E11D, K14R, A21T, V31I, I72V, T112V, T124N, T125A, G134N, I135V, K136R, D167E, V201I, K215N, L234I, S283G  
114 VNR114 None    E11G, W19R, S39N, I72V, T112V, T124A, T125A, V126L, G134N, I135V, K136R, M154I, V165I, D167E, V201I, L234I, S283G A21R 
1209248 KCS1209248 None    E10D, K14R, A21T, V31I, I72V, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136R, G163GE, V165I, D167E, V201I, L234I, S255T, S283G L2F, S195SI 
1212047 KCS1212047 None   N155I K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, K156R, E157G, D167E, V201I, L234I V150E, E152H, S153L, M154P 
1230214 KCS1230214 None    K7Q, E11D, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, G193D, S195C, V201I, L234I, D279DG, S283G K46K* 
1231245 KCS1231245 None    K14R, V31I, I72V, T112V, T125A, V126L, G134N, I135V, K136R, M154I, V201I, L234I, S283G  
128059 KCT0128059 None    K14R, A21T, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136R, E157Q, K160T, D167E, V201I, K215N, L234I, S283G  
128107 KCT0128107 None    E11D, A21T, V31I, V37VI, S39N, I72V, L101V, T112V, T124A, T125A, G134N, I135V, K136Q, V165I, D167E, V201I, L234I, S283G  
128245 KCT0128245 None    K14R, A21T, V31I, I60M, I72V, T112V, T124A, T125A, V126F, G134N, I135V, K136Q, V165I, D167E, V201I, L234I, S283G E69EK, A80AP, G106GE, E152EK 
21 KC21 None    K14R, A21T, V31I, S39N, K46KR, I72V, T112V, T124A, T125A, G134N, I135V, D167E, V201I, L213LF, R224RW, L234I, D253E, S283G E85EQ, A86AP, E87EK, E212EK, L242LF, E246EK 
213216 KCT0213216 None    K14R, A21T, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, I200L, V201I, I203IM, I204L, T206S, L234I, S255T, S283G  
24 VNR24 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, S283G, Q285R G277S 
29 VNR29 None    K14R, A21T, V31I, V32I, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, S283G  
KC03 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, S283G  
31 VNR31 None    E11D, K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, V126L, G134N, I135V, K136R, V165I, D167E, V201I, L234I, D256E, S283G G277GS 
32 VNR32 None    K14R, A21T, V31I, S39N, Q95A, Y99F, L101I, T112V, T124A, T125A, G134DN, I135V, K136R, V165I, D167E, V201I, L234I, D253E, N254H, S255R, Q274R, Q285P M22MT, R228EG, G237GR, P238PT, R262G 
327158 KCT0327158 None    E11D, K14R, A21T, V31I, S39N, I72V, T112V, T125A, G134N, I135V, K136R, K160Q, Q164K, V201I, L234I, S283G E212ED 
330257 KCT0330257 None    E11D, K14R, A21T, M22L, V37I, I72V, T112V, T124N, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
36 VNR36 None    E11G, V31I, V32VI, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, V201I, L234I, S283SG, Q285QR G277GS 
37 VNR37 None    K14R, A21T, V31I, E35G, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
38 VNR38 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, K160R, D167E, V201I, L234I, Q252R, Q274R, G277C, S283G  
403298 KCT0403298 None    K14R, A21T, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, V201I, L234I, S283G  
428200 KCT0428200 None    K14R, A21T, V31I, S39N, I72IV, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203IM, L234I, S283G, R284RG  
48 KC48 None    E11D, K14R, A21T, V31I, M50I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, K236R, S283G  
49 KC49 None   L68I E11D, K14R, A21T, V31I, I73V, T112V, T125A, G134N, I135V, K136R, D167E, V201I, L234I, D256E, S283G  
50 KC50 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, V126VM, G134N, I135V, K136Q, D167E, V201I, L234V, V259I, S283G  
52 KC52 None    E11D, K14R, A21T, V31I, S39N, S57N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, S153SF, G163E, D167E, V201I, L234I, S283G D202DV 
520294 KCT0520294 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, K160Q, Q164K, D167E, R187K, V201I, L234I, S283G, D288N  
522056 KCT0522056 None    E11D, A21T, S24G, D25E, S39N, L45Q, I72V, T112V, T124N, T125A, G134N, I135V, K136R, V165I, D167E, V201I, Q209QP, L234I, S283G K211I 
522058 KCT0522058 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136H, D167E, V201I, L234I, S283G  
522471 KCT0522471 None    K14R, N18H, M22L, V31I, I72V, T112V, T124A, T125A, V126M, G134N, I135V, K136R, V165I, D167E, V201I, Q216H, R224RW, L234I, S283G, R284G A21P, H183HLPR, K186KI 
53 KC53 None    K14R, A21T, I72V, T112V, T124A, T125A, V126M, G134N, I135V, K136R, D167E, V201I, L234I, S283G A8AP 
55 KC55 None    K14R, A21T, V31I, S39N, I72V, T112V, T125A, V126VI, G134N, I135V, K136Q, D167E, V201I, L234IV, V259VI, S283G T124AD 
56 KC56 None    E11D, K14R, A21T, V31I, V32I, S39SN, I72V, T112V, T124A, T125A, G134N, I135V, K136QR, D167E, V201I, L234I, V259I, S283G  
59 KC59 None   V151VI E11D, K14R, A21T, V31I, S39N, L45V, I72V, T112V, T124TA, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
60 VNR60 None    K14R, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
61 KC61 None    K14R, R20K, A21T, I72V, T112V, T124N, T125A, G134N, I135V, K136R, D167E, V201I, L234I, N254K, S283G  
  VNR61 Unknown   V151I K14R, A21T, V31I, S39N, I72V, L101V, T112V, T125A, G134N, I135V, K136R, V165I, D167E, V201I, L234I, K273N, S283G, R284G D25L, G272E 
63 KC63 None    K14R, A21T, V32I, I72V, T112V, T124A, T125A, K127R, G134N, K136Q, S153SF, V165I, D167E, V201I, I208M, R224RW, L234I, V281VG, S283G L241LI 
64 KC64 None    K14R, A21T, S39N, I72V, L101I, T112V, S123C, T124N, G134N, I135V, D167E, H171Q, I200M, V201I, T206S, L234I, S283G  
67 KC67 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, K160KR, V165VI, D167E, V201I, L234I, S283G  
68 VNR68 None    D6E, K14R, A21T, A23V, E35G, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, V201I, L234I, S283G I5K, G247R 
78 VNR78 None    K14R, W19R, A21T, V31I, S39N, L63V, T112V, T124A, T125A, G134N, I135V, K136R, V165I, A196P, V201I, L234I, S283G  
79 VNR79 None    K14R, A21T, D25E, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, S283G  
84 VNR84 None    K14R, W19R, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G M22T 
85 VNR85 None    E11D, K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
87 VNR87 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
92 VNR92 None    K14R, A21T, S39N, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, I208L, L234I, K240KR, E246G, N254D, A282P, S283SG, Q285R G247GR, R262G, G277GS