Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Niama (2009)
Title CRF45_AKU, a circulating recombinant from Central Africa, is probably the common ancestor of HIV type 1 MAL and HIV type 1 NOGIL.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 4
NumPts 4
Subtype CRF45_cpx


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
97CD.MBFE185 CD.MBFE185 None None   V35T, T39I, V60I, K173V, Q174K, D177E, T200I, Q207E, V245Q, E248N, D250E, S251N, A272P, K277R, T286A, E291D, V292I, I293V, E297V, A304AE, F346Y, M357I, R358K, G359A, T377Q, K390R, A400T, K431P, L452M, K465Q, L469I, D471E, T477A, L491S, E516D, S519N, K527Q, E529D, A534S, A554S  
97CD.MBS30 CD.MBS30 None None   V35T, T39M, K49R, V60I, I135T, K173I, Q174K, D177E, T200I, Q207E, R211K, V245Q, E248D, D250E, A272PS, V276I, T286A, E291D, V292I, I293V, E297A, A327V, E328D, G335D, F346Y, A355T, M357A, G359S, I375V, T377R, K390R, A400T, K431T, L452K, D471E, H483Q, L491P, V496I, E516D, S519N, K527Q, E529N, A534S, A554N  
97CM.MP814 CM.MP814 None None   K20R, V35K, T39TKN, V60I, D121H, K122E, D123S, S162C, E169EG, K173E, Q174K, D177E, Q207E, R211K, V245Q, E248D, D250E, K281R, T286A, A288S, E291D, V292I, I293V, E297A, V317A, Q334H, F346Y, M357I, R358K, G359S, E370D, T377M, K390R, A400T, K431T, V435L, L452Q, V458VI, D471E, H483Y, L491A, K512T, S519N, K527Q, E529D, A534S, A554N  
97GA.TB45 GA.TB45 None None   E6N, V8I, K11Q, V35T, K49R, V60I, K122E, D123N, F171Y, K173T, Q174R, T200I, Q207E, R211K, V245Q, E248D, D250E, A272P, K277R, E291D, V292I, I293V, P294S, E297T, S322A, F346H, M357T, R358K, G359A, K366KR, T377Q, K390R, A400T, K431T, L452Q, D471E, L491S, E516D, S519N, K527Q, E529D, A534S, A554S