<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Low (2009)
Title Natural polymorphisms of human immunodeficiency virus type 1 integrase and inherent susceptibilities to a panel of integrase inhibitors.
Citation AAC
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 133
NumPts 132
Subtype B, CRF02_AG, A

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Page 1   from Isolate 1 to Isolate 100 from Total 133 Clinical IN Isolates

SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
A-6 A-6 None    M154I, V201I  
ahi1 ahi1_06 None    P90T, L101I, S119R, K156N, V201I  
ahi10 ahi10_06 None    E11D, M50I, A91V, L101I, K111T, T124A, K211R, Q216N  
ahi12 ahi12_06 None    S17N, L28I, S39C, I72V, T124A, V201I, A265V  
ahi13 ahi13_05 None    S17N, I72V, F100Y, L101I, T124N, I141T, V150A, V201I, T206S, I208L, D256E S283G 
ahi14 ahi14_06 None    E11D, I60M, I113V, T124A, V126F, V165I, T206S  
ahi15 ahi15_04 None    K34R, M50I, V201I, S230N, D256E  
ahi16 ahi16_99 None    S17N, T124A, T125A, K156N, S230N  
ahi17 ahi17_01 None    S17N, V32I, T124A, V201I, D256E  
ahi18 ahi18_02 None    E11D, V37I, I60V, I72V, T112C, T122I, T125A, E157Q, K160Q, L172I, A205S, K211R, S230N  
ahi19 ahi19_06 None    E10D, S39R, L45R, M50I, I72V, L101I, K111T, S119G, T218I  
ahi2 ahi2_06 None    D6E, E10D, S24G, M50I, I72V, L101I, S123C, K156N  
ahi20 ahi20_06 None    K7Q, E11D, V31I, V32I, S39C, T124A, F185V, V201I S283N 
ahi21 ahi21_03 None    P30A, V32I, T125A, K156N, E157Q, K188R, V201I, K215N, N222K, S230N, M275V  
ahi22 ahi22_02 None    E11D, V31I, I60V, T93N, L101I, K111T, T122I, T124A, H171Y, Q216H, D256E  
ahi23 ahi23_96 None    K14R, S24N, A49P, L101I, T112I, T124A, T125V, V126A, T218S, N222K R284G 
ahi24 ahi24_03 None    S17N, S39N, I72V, T112I, T124A, V126M, K173R, V201I  
ahi25 ahi25_96 None   L68V D6E, L28I, S39C, L45I, L101I, K156N, N254Q  
ahi26 ahi26_05 None    E11D, S24N, P30S, T112I, V201I, T206S  
ahi27 ahi27_99 None    S24G, D25E, S39C, I72V, L101I, T112A, T125A, A205S  
ahi28 ahi28_01 None    E11D, S24N, M50T, I72V, A91T, L101I, S119P, T122I, T124A  
ahi29 ahi29_01 None    E10D, V31I, L101I, T112V, S119G, T122I, T124N, K219N, I220L, N222K  
ahi30 ahi30_96 None    Q216H R284G 
ahi31 ahi31_05 None    E10D, V31I, V32I, S39R, I72V, L101I, K111T, T122I, T125A, T218I  
ahi32 ahi32_05 None    E11D, S17N, V31I, I72V, T124N, K211R, A265V  
ahi33 ahi33_06 None    E11D, D25E, V31I, L101I, V201I, T206S, K215N, D256E, I268L R284G, D286N 
ahi34 ahi34_05 None    D6E, E10D, T124N, T125M, G163E  
ahi38 ahi38_99 None    E11D, S24N, V31I, M50I, Y99F, L101I, T124A, V201I, K211Q  
ahi39 ahi39_01 None    E11D, S24N, M50T, I72V, A91T, L101I, S119P, T122I, T124A  
ahi4 ahi4_98 None    V31I, I72V, L101I, I113V, T124N, T125M, L172I, K188R, L234I, A265V  
ahi40 ahi40_06 None    L45I, L101I, I113V, T124N, T125A, F181L, V201I, A205S, D232E  
ahi41 ahi41_06 None    V31I, S39C, T124A, E157Q, G163Q, V201I, D232E  
ahi42 ahi42_06 None   V54I E11D, V31I, M50I, L101I, K111T, S119G, T124N, T125V, F181L, K219Q, N222K  
ahi43 ahi43_06 None    L45V, M50I, G163E, I208L D286N 
ahi44 ahi44_00 None    T124A, T125A, K156N, S230N  
ahi45 ahi45_02 None    E11D, V31I, M50I, L101I, G163E, F181L, V201I, A205S, T206S, T218S, S230N  
ahi46 ahi46_96 None    E11D, S24N, V32I, M50T, L101I, S119P, T122I, V201I, D256E  
ahi47 ahi47_01 None    I113V, T124N, T125A, I200M, V201I  
ahi48 ahi48_01 None    E10D, V31I, M50V, I72V, V79A, L101I, T122I, T124A, V201I, T206S, I208L, T218S, I220L, Y227F, L234I  
ahi49 ahi49_03 None    K7R, S17N, I72V, T112I, T124A, K173R, V201I  
ahi5 ahi5_03 None    E11D, V31I, M50I, A91E, L101I, K111Q, S119R S283G 
ahi50 ahi50_06 None    S17N, V31I, L101I, K111T, T124N, G163T, V201I, I220L, D232E  
ahi51 ahi51_06 None   L68V M50I, I73V, V201I  
ahi52 ahi52_98 None    E10G, K14R, V32I, E96D, L101I, K103R, T124N, T125A, I135V, G193R, T206S, I208L, S230N  
ahi53 ahi53_07 None    V31I, I72V, K111T, I113V, T124A, T206S  
ahi54 ahi54_06 None    M50T, T112M, T125V, K156R, K215N, I220L, Q221H  
ahi55 ahi55_06 None    I72V, I208L  
ahi56 ahi56_99 None    K34R, V201I  
ahi57 ahi57_00 None    E11D, S24N, V32I, S119P, V201I, T218S, S230N, D232E, D256E  
ahi58 ahi58_01 None    D6K, E10D, D25N, M50I, I72V, L101I, S123C, K156N, T206S  
ahi59 ahi59_01 None    E11D, S24N, L101I, S119P, T122I, T124N, T125A, K136N  
ahi6 ahi6_00 None    S17N, V31I, M50I, I72V, T122I, T124N, T125A, K211R, S230N, A265V  
ahi60 ahi60_06 None    S17N, S39R, M50T, I72V, T122I, T124N, K156N, I220L, Y271S K266E, E287Q 
ahi61 ahi61_06 None    Q9QP, E10D, L45V, I72V, K156N, V201I, I203M, I208L, E212A, S255R  
ahi62 ahi62_06 None    E11D, V31I, L101I, T112V, S119R, T124A, T125A, G134N, I135V, K136T, E157Q, K160Q, V201I, I203M, T206S, I208L, T218I, L234I, A265V S283G, D288N 
ahi63 ahi63_01 None    K14R, L28I, V32I, S39C, I72V, L101I, S119P, T122I, T124A, V201I, K240R  
ahi64 ahi64_98 None    S17N, N27D, L45V, L101I, K136N, T206S, I208L, E212A, D256E  
ahi66 ahi66_06 None    D6E, E10D, L101I, K111R, S119G, T122I, T124N, T125A, D167E, I220L  
ahi67 ahi67_01 None    E11D, S17T, V31I, M50I, T124N, T125V, V126M, G163E, D256E  
ahi68 ahi68_06 None    M50I, K211R, S230N, I251L  
ahi69 ahi69_99 None    E11D, S24N, L101I, S119P, T122I, T125A, K136N  
ahi7 ahi7_99 None    E11D, A21T, A23V, D25E, L101I, S119G, T122I, T125A, G193E, T206S, L234V, D256E, D279G  
ahi70 ahi70_01 None    E11D, V31I, M50I, L101I, G163E, F181L, V201I, A205S, T206S, T218S, S230N  
ahi72 ahi72_96 None    K7R, S17N, I72V, K111T, I113V, T124A, T125A, T206S  
ahi73 ahi73_01 None    E11D, S24N, V31I, M50T, A91T, T206S, S230N, D232E, K273Q, D278N S283G 
ahi75 ahi75_97 None    L45V, M50I, L101I, T124N, G163E, V201I, I208L, T218S, D256E, I267V  
ahi76 ahi76_02 None    D6E, E10D, M50I, I72V, L101I, S123C, K156N  
ahi77 ahi77_98 None    S17N, L68T, L101I, S119P, T122I, T124N, T125A, N254Q, S255G  
ahi78 ahi78_06 None    S17N, D25E, L45I, I72V, T93K, L101I, K111R, T124A, K156N  
ahi79 ahi79_05 None    S17N, L28I, P30A, I72V, L101I, T124A, I135V, K156N, V201I  
ahi8 ahi8_06 None    R20K, S119T, K156N, T206S, I208L, E212A  
ahi80 ahi80_06 None    S17N, R20K, I72V, S119T, T124N, T125A, V126L, K156N, V201I, S230N, D256E V281M 
ahi81 ahi81_05 None    L101I, T124A, G193E, I203M, Q216R, D256E  
  ahi81_06 Unknown    E11D, D25E, V31I, L45Q, L101I, T125A, V201I, K215T, S230N, L234I, D270H T115A 
ahi82 ahi82_02 None    S17N, I72V, T124A, K188R, V201I, S230N K264R 
ahi83 ahi83_05 None    E11D, S24N, I72V, K156N, V201I, I208L, N254Q, S255G  
ahi84 ahi84_06 None    V31I, I72V, V75I, L101I, K156N  
ahi85 ahi85_03 None    S17N, I72V, L101I, T124A, K156N, V165I, V201I, I203V, T206S, D207E, I208L, D256E  
ahi86 ahi86_97 None    R20K, L101I, S119T, A265V  
ahi87 ahi87_01 None    D6E, E10D, M50I, I72V, L101I, S119P, K156N  
ahi88 ahi88_05 None    M50I, I72V, I73V, P90A, T125A, V201I, S230N V225I 
ahi89 ahi89_05 None    E11D, K14R, V31I, S39C, T112I, I113V, T124A, T125A, K136Q, V201I, Q216H, L234I S283G 
ahi9 ahi9_02 None    K14R, L28I, P30A, S39C, I72V, T124A, I203M, T206S, I208L S283G 
ahi90 ahi90_04 None    E11D, S17T, V31I, L101I, K111N, S119G, T122I, K219N, N222K  
ahi91 ahi91_03 None    E11D, S24N, K156N, V201I, T206S, T218S  
ahi92 ahi92_03 None    E11D, S24N, S119T, V201I, T206S, I217V, T218S, D256E S283G, R284G 
ahi93 ahi93_04 None    M50I, K211R, T218I, S230N, I251L, A265V  
ahi94 ahi94_04 None    D6E, V37I, I72V, G106A, V201I R284G 
ahi95 ahi95_04 None    V31I, V32I, V110I, T124N, T125I, L234I, A265V  
ahi96 ahi96_03 None    S17N, I72V, T124N, T125A, I135V, M154L, V201I  
ahi97 ahi97_04 None    M50I, T112I, K156R, K173R, I220V  
ahi98 ahi98_03 None    E10D, A49P, I72V, V201I, T218S, D256E R284G 
ahi99 ahi99_04 None    L28I, S39C, I72V, T124N, I135V, I203M, Q216H  
B-27 B-27 None    R20K, S39C, T124N, T125V, V201I  
F-15 F-15 None    I72V, T124N, T125A, V126L, M154L, V201I, T206S, C280S  
G-4 G-4 None    S39C, I72V, L74I, T124A, K156R, K215N, T218I, L234I  
G-8 G-8 None    I72V, L101I, S119T, M154L, V201I S283G 
N-19 N-19 None   V151I E11D, D25E, V31I, I72V, I113V, S119G, T124N, V201I  
R-31 R-31 None    E11D, V32I, V37I, L101I, T112I, T124N, T125A, K173R, A205S, Q216H, N222K, S230N  
R-6 R-6 None    E11D, S17N, A23V, L28I, P30A, L101I, S119T, T122I, V201I, N222K, S230G, D253E, N254G  

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