<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Weber (2003)
Title Role of baseline pol genotype in HIV-1 fitness evolution.
Citation JAIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 25
NumPts 10
Subtype B, A, C, CRF05_DF

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
00F 610500F-0 NRTI None   E44D, R83K, D121Y, K122E, T165I, Q174K, D177E, R211K, V245M, K277R, T286A  
  610500F-12 NRTI, AZT, 3TC None   E44D, R83K, D121Y, K122E, Q174K, D177E, R211K, V245M, K277R, T286A  
  610500F-24 NRTI, AZT, 3TC None   V35I, E44D, R83K, D121Y, K122E, Q174K, D177E, R211K, V245M, K277R, T286A  
  610500F-48 NRTI, AZT, 3TC None   V35I, E44D, R83K, D121Y, K122E, K166Q, Q174K, D177E, R211K, V245M, D250E, K277R, T286A  
1C IRIS1C-0 None None   A158S, I178IM, Q207H, R211K  
  IRIS1C-48 D4T, 3TC None   A158S, I178M, Q207H, R211K  
2S IRIS2S-0 None None   V35T, K122E, I135V, S162C, K173I, Q174K, Q207E, R211K  
  IRIS2S-48 3TC None   V35T, K104R, I135V, S162C, K173I, Q174K, Q207E, R211K  
3M IRIS3M-0 None None   E6K, K11T, V35T, T39E, K122E, D123N, S162C, K173S, D177E, T200A, I202V, Q207A, R211S E194E* 
  IRIS3M-24 D4T None   E6K, K11T, V35T, T39E, K122E, D123S, S162C, K173S, D177E, T200A, I202V, Q207A, R211S  
4L IRIS4L-36 D4T, 3TC None   V35T, T39I, E40D, S48T, K49R, V60I, T139TA, D177E, Q197K  
5W IRIS5W-48 AZT, 3TC None M184V  P4T, K11T, V21I, V35T, E40D, K49R, V60I, V90I, K122E, D123S, I135T, K173S, D177E, T200A, Q207A  
63J 610363J-0 NRTI None   K11Q, V35M, P55PS, R83K, E169D, G196E, R211K, I293V  
  610363J-12 NRTI, AZT, 3TC None   K11Q, V35M, R83K, K122E, E169D, G196E, R211K, I293V, E297Q  
  610363J-24 NRTI, AZT, 3TC None   K11Q, V35M, R83K, E169D, G196E, R211K, I293V, E297Q  
  610363J-48 NRTI, AZT, 3TC None   K11N, V35M, R83K, E169D, G196E, R211K, I293V  
71K 610471K-0 NRTI None D67N, K70R, T215F, K219Q  K20R, V35L, K64Y, I135V, I202V, L228H, T286A  
  610471K-12 NRTI, AZT, 3TC None D67N, K70R, T215F, K219Q  K20R, V35I, K64Y, I135V, I202V, L228H, T286A  
  610471K-24 NRTI, AZT, 3TC None D67N, K70R, T215Y, K219Q  K20R, V60I, I135V, I202V, T286A  
  610471K-48 NRTI, AZT, 3TC None D67N, K70R, M184V, T215F, K219Q  K20R, K64H, I135V, I202V, L228H, T286A  
85H 610185H-0 NRTI None M41L, L210W, T215Y  V35T, T39E, S48T, A98S, K122E, D123N, I135T, K173T, Q174K, T200A, Q207N, R211K, V245Q, A272Q, E291D, V292I, I293V  
  610185H-12 NRTI, AZT, 3TC None M41L, D67N, L210W, T215Y  V35T, T39E, S48T, A98S, K122E, D123N, I135T, K173T, Q174K, T200A, Q207N, R211K, V245Q, A272Q, E291D, V292I, I293V  
  610185H-24 NRTI, AZT, 3TC None   V35T, E36A, T39E, S48T, K122E, D123N, K173T, Q174K, T200A, Q207E, V245Q, A272Q, K277R, E291D, V292I, I293V  
  610185H-48 NRTI, AZT, 3TC None M41L, D67N, M184V, L210W, T215Y  V35T, T39E, S48T, A98S, V118I, K122E, D123N, I135T, K173T, Q174K, N175Y, G196E, T200A, Q207N, R211K, V245Q, A272Q, E291D, V292I, I293V  
SI IRIS6I-48 3TC None M184V  V35T, I47IL, S48T, V60I, K122E, D123S, I135T, I142V, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S  

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