<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Fransen (2012)
Title HIV-1 mutations at positions 143, 148, and 155 of integrase define different genetic barriers to raltegravir resistance in vivo.
Citation Journal of Virology
SelectedGene IN
SelectedSpecies HIV1
SelectedType Lab
NumIsolates 10
Lab Parent Strain NL43

Lab IN Isolates (including Susceptibility Data)

IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
N155H N155H V151I PhenoSense RAL 20 
N155H+E92Q E92Q, N155H V151I PhenoSense RAL >200 
Q148H Q148H V151I PhenoSense RAL 20 
Q148H+G140S G140S, Q148H V151I PhenoSense RAL >200 
Q148R Q148R V151I PhenoSense RAL 30 
Q148R+G140S G140S, Q148R V151I PhenoSense RAL >200 
Y143C Y143C V151I PhenoSense RAL 3.5 
Y143C+T97A Y143C T97A, V151I PhenoSense RAL >200 
Y143R Y143R V151I PhenoSense RAL 20 
Y143R+T97A Y143R T97A, V151I PhenoSense RAL >200