Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Fransen (2012)
Title HIV-1 mutations at positions 143, 148, and 155 of integrase define different genetic barriers to raltegravir resistance in vivo.
Citation Journal of Virology
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 10
Lab Parent Strain NL43


Lab IN Isolates : Susceptibility Data

IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
N155H N155H  PhenoSense RAL 20 
N155H+E92Q E92Q, N155H  PhenoSense RAL >200 
Q148H Q148H  PhenoSense RAL 20 
Q148H+G140S G140S, Q148H  PhenoSense RAL >200 
Q148R Q148R  PhenoSense RAL 30 
Q148R+G140S G140S, Q148R  PhenoSense RAL >200 
Y143C Y143C  PhenoSense RAL 3.5 
Y143C+T97A Y143C T97A PhenoSense RAL >200 
Y143R Y143R  PhenoSense RAL 20 
Y143R+T97A Y143R T97A PhenoSense RAL >200