Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Fransen (2012)
Title HIV-1 mutations at positions 143, 148, and 155 of integrase define different genetic barriers to raltegravir resistance in vivo.
Citation Journal of Virology
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 5
NumPts 5
Subtype B


Clinical IN Isolates

pt1 pt1 RAL  E92EQ, Y143YR, N155NH V151VI, G163GK S17N, S39C, L101I, T124N, V201I, L234V W243L 
pt2 pt2 RAL  Y143YR, N155NH Q95QK, V151I, G163GR E10D, V31I, L101I, M154I, V165I, V201I  
pt3 pt3 RAL  G140GS, Q148QHR, N155NH V151I E11D, A21T, A23AV, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D278E  
pt4 pt4 RAL  E92EQ, G140GS, Y143YR, Q148QR, N155NH V151I S17N, V31I, V79VI, L101I, T124A, L234I  
pt5 pt5 RAL  G140GS, Y143YR, Q148QH, N155NH V151I, G163GR E10D, K14R, A23V, L28I, P30A, S39C, L101I, T124A, F185Y, V201I, T206S, Q216H