Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Mintsa-Ndong (2009)
Title High HIV Type 1 prevalence and wide genetic diversity with dominance of recombinant strains but low level of antiretroviral drug-resistance mutations in untreated patients in northeast Gabon, Central Africa.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 15
NumPts 15
Subtype CRF02_AG, A, D, F, K, CRF11_cpx, CRF06_cpx


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
MKK115 MKK115 None None   V35T, K49R, V60I, I135V, T165TI, K173T, Q174E, D177E, T200A, Q207E  
MKK169 MKK169 None None   V35K, E36D, T39A, I135L, T139I, S162A, K173A, Q174K, D177E, T200A, Q207E, V245Q  
MKK192 MKK192 None None   T27S, V35T, E36D, V60I, K104T, K122E, I135V, S162A, E169A, K173T, Q174K, D177E, I178V, T200A, Q207E, R211K, F214L, V245Q  
MKK222 MKK222 None None   E6D, V35T, K122E, D123S, K173A, Q174K, D177E, T200E, I202V, Q207E, I244L, V245L D186G 
MKK227 MKK227 None None   K20R, V35T, S48F, D121Y, I142N, K173E, Q174R, D177E, T200I, Q207E, R211K, F214L, V245C V60Y 
MKK235 MKK235 None None   V35T, E40D, K49R, V60I, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207G, R211K, V245M  
MKK24 MKK24 None None   V35T, D123DE, S162F, K173I, Q174K, Q207D, R211K, P243Q, V245P  
MKK248 MKK248 None None   K11T, V35T, T39N, E40D, K49R, K122E, D123G, K173S, D177E, Q207N, V245Q  
MKK27 MKK27 None None   K20R, V35T, K49R, V60I, S162A, K173E, Q174QE, D177E, T200A, Q207E, R211K G141GR, W229L 
MKK274 MKK274 None None   V35T, T39K, D121DY, K122KE, I135T, T139TI, E169D, K173A, Q174K, D177E, G196E, Q207A, R211S, V245P, E248D  
MKK332 MKK332 None None   V35T, T39K, K122E, S162C, K173T, Q174R, D177E, I178M, T200A, Q207K, R211A  
MKK351 MKK351 None None   E6K, V35K, E36D, K43KR, K122E, I142V, S162A, K173T, Q174K, D177E, T200A, I202V, Q207N  
MKK85 MKK85 None None   K20R, V35T, K103R, D123DE, I135V, S162A, K173T, Q174K, D177E, T200A, Q207D, R211K, F214L, V245E  
MKK90 MKK90 None None   V35T, K49R, V60I, D123E, I135T, S162C, R172K, D177E, I178L, T200A, E204K, Q207E, F214L, V245T G93R 
MKK93 MKK93 None None   V35T, E36D, T39TA, I135L, T139TI, S162A, K173AT, Q174K, D177E, T200A, Q207E, T240TA, V245Q, E248D T84TA