<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Church (2008)
Title Analysis of nevirapine (NVP) resistance in Ugandan infants who were HIV infected despite receiving single-dose (SD) NVP versus SD NVP plus daily NVP up to 6 weeks of age to prevent HIV vertical transmission.
Citation J Infect Dis
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 49
NumPts 49
Subtype A, D, C


Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
318990H 318990H None NVP   V35T, K49R, V60I, K122E, I135T, T165I, D177E, T200A, Q207E, V245K, D250E, A272P, T286A, E291D, V292I, I293V, E312D  
326163-M 326163-M None NVP   K11T, K20R, V21I, V35T, T39K, K122E, D123N, K173S, D177E, V179I, T200K, I202V, Q207D, V245Q, E248D, D250E, T286A, E291D, V292I, I293V, P294A, E312D  
330957-Y 330957-Y None NVP   E6A, T7A, V35T, K49R, V60I, D121Y, K122E, R125K, I135T, K166R, D177E, I178M, T200I, Q207E, R211K, F214L, I244V, V245EK, D250E, S251DN, A272PS, K277R, L282C, T286A, I293V  
335346R 335346R None NVP   K11S, V35T, E36ED, T39TS, K49R, K122E, D123N, I135T, I142V, K173AT, Q174K, D177E, V179I, Q207A, R211S, V245Q, A272PS, K281R, K287R, P294T, E312D E29D 
341741Y 341741Y None NVP  K103KN, V106VA, Y181YC I2V, E6D, V35T, E40D, K49R, V60I, V118M, I135V, T165I, K173S, Q174K, D177E, T200A, I202V, Q207K, R211S, F214L, V245K, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E312D, A327V  
347758P 347758P None NVP  Y188N V35T, V60I, I142V, D177E, T200I, Q207E, R211K, V245Q, E248N, D250E, A272P, K275R, K277R, Q278H, L282C, L283I, K287R, I293V, P294S  
349844H 349844H None NVP  K103KN, Y181YC P4PH, E6EDKN, V35T, V60VI, K64KR, K102KQ, K122E, D123S, I135T, I142IT, S162SAGT, K173A, Q174K, V179I, Q207A, R211S, V245Q, A272S, T286A, E291D, V292I, I293V, E312D  
354756Q 354756Q None NVP   E6D, K11R, K20R, V21I, V35I, T39D, D121C, K122E, R125K, S162C, Q174QR, D177E, I178M, V179VAIT, I202V, Q207E, R211K, V245K, D250E, A272P, K277R, K281R, L282C, L283I, T286A, I293V, E297K, S322A  
359642T 359642T None NVP  K103N V21I, V35T, V60I, K122E, D123S, S162A, D177E, I178M, Q207E, R211K, V245Q, E248N, T286A, A288S, E291D, V292I, I293V, D320E, D324E  
361159H 361159H None NVP   P4S, K11R, V35T, D123S, I135T, E138A, K173S, D177E, V179I, Q207A, R211S, V245K, D250E, A272P, K277R, L282C, T286A, I293V  
361358A 361358A None NVP  Y181C V21I, V35T, K49R, I50V, V60I, K122E, D123S, E169D, K173A, Q174K, D177E, V179I, I202V, Q207A, R211S, V245E, D250E, A272P, K277R, L283I, I293V, K311R, E312N, S322A  
362363H 362363H None NVP  Y181C K11T, K20R, V21I, V35T, T39R, D123N, S162SC, K173S, D177E, V179I, T200A, I202V, Q207A, R211K, V245E, D250E, T286A, E291D, V292I, I293V, P294T, K311R, E312D  
363290D 363290D None NVP   E6D, V35T, T39A, V60I, K122E, D123G, I135T, S162C, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, D250E, T286A, E291D, I293V, P294T  
365770P 365770P None NVP  K103N V35T, T39L, V60I, D121Y, K122E, I135T, K173S, Q174K, D177E, T200A, Q207A, R211S, V245M, E291D, V292I, I293V  
366975Y 366975Y None NVP  Y181YC, G190GA K11T, K20R, V21I, V35T, T39G, K122E, D123N, K173S, Q174K, D177E, V179I, T200A, I202V, Q207A, R211N, V245Q, E248D, T286A, E291D, V292I, I293V, P294T, E312D, D324E, I326V  
367927-J 367927-J None NVP  Y181C K20R, V21I, V35T, T39R, K43E, V60I, I135R, S162A, K173S, Q174K, V179I, Q207A, R211S, V245Q, D250E, S251D, E291D, V292I, I293V, P294T, E312D, D320E, D324E  
368341X 368341X None NVP  Y188C V35T, T39M, V60I, I135V, D177E, Q207E, R211K, V245K, D250E, A272P, K277R, L282C, V292I, E297A Q145S, Y146T 
369096E 369096E None NVP   P4H, K11T, V35T, V60I, K122E, D123S, K173T, D177E, I202V, Q207A, R211S, V245Q, E248D, K281R, T286A, E291D, V292I, I293V, P294T, A304E, E312N, Y319F, S322L  
370579W 370579W None NVP   E6D, V35T, E36D, K49R, I50V, V60I, K122E, I135T, D177E, T200I, Q207E, R211K, F214L, I244V, V245E, E248D, D250E, A272P, L282C, R284K, T286A, I293V  
370581-G 370581-G None NVP   V35T, T39E, K49R, V60I, K104R, D121Y, K122E, D123E, I135T, I142V, D177E, I178M, T200I, Q207E, R211K, V245K, D250E, A272P, K277R, L282C, L283I, T286A, I293V, E297A, L310I, I329V  
372195-P 372195-P None NVP  Y181YC I5V, E6D, V35T, K49R, V60I, K103R, D121Y, K122E, D177E, I178M, T200I, Q207G, R211K, I244V, V245T, D250E, L260I, A272P, L282C, I293V, A304E, D324E  
377986-M 377986-M None NVP  K103KN, Y188YC V35T, V60I, K122E, D123S, I135T, P170S, K173A, Q174K, D177E, V179I, T200I, Q207E, V245K, D250E, T286A, E291D, I293V, P294A, E297K, A304E, E312D  
378519C 378519C None NVP  Y181C V60I, S68SN, D121Y, K122E, I135T, S162A, K173S, Q174K, D177E, I178M, T200A, Q207A, R211S, V245T, E248D, D250G, A272P, L282C, T286A, I293V  
380521-H 380521-H None NVP  V106VA, Y181YC K11T, K20R, V21I, V35T, T39K, K43E, D123N, K173S, D177E, V179I, T200A, I202V, Q207A, V245HQ, E248D, D250DE, T286A, E291D, V292VI, I293V, P294T  
387519-L 387519-L None NVP  K103KN, Y181YC K11T, K20R, V21I, V35T, T39R, K43E, K122E, D123N, K173A, D177E, V179I, T200TA, I202V, Q207A, V245Q, E248DN, D250E, S251SN, T286A, E291D, V292I, I293V, P294T, E312S  
389271-L 389271-L None NVP  Y181C V35T, T39S, V60I, D121Y, K122E, I142V, K166R, D177E, I178M, Q207E, R211K, V245K, D250E, A272P, K277R, L282C, T286A, I293V, E297A, D324E  
390900V 390900V None NVP  Y181C K11T, V35T, E40D, K43R, T139I, K173S, D177E, V179I, T200A, Q207A, R211S, F214L, V245Q, A272T, E291D, I293V, P294T, E312D, D320E  
391100H 391100H None NVP  G190A V35T, T39L, V60I, D121Y, K122E, D177E, I178M, Q197K, Q207G, R211K, V245K, D250E, S251N, A272P, V276T, K277R, L282C, L283I, T286A, I293V  
393395X 393395X None NVP  K101E V35T, K49R, V60I, D121H, K122E, D177E, I178M, T200I, Q207E, R211K, V245K, D250E, A272P, V276I, K277R, L282C, L283I, T286A, I293V, E297K, D324DN  
394901B 394901B None NVP  K103KN, Y181YC K20R, V21I, V35T, T39K, V60I, K122E, D123N, I135T, K173S, Q174R, D177E, I178L, V179I, T200A, I202V, Q207A, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294T, E312D  
400177E 400177E None NVP  K103KN, Y181C P4S, V21I, K32R, V35T, T39A, E40D, V60I, T107S, K122E, D123N, I142V, K173A, Q174K, D177E, T200A, Q207E, R211K, H221HY, V245E, D250E, T286A, E291D, I293V, E312D, I329V  
400196E 400196E None NVP  K103KN, V106VA E6N, V35T, K49R, V60I, K64R, K122E, D123S, I135T, I142V, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, D250E, A272P, E291D, I293V, P294T, E312D  
402787T 402787T None NVP  Y181YC V35T, S48E, K49R, E53D, V60I, K122E, D123S, D177E, I178M, G196K, T200A, Q207E, V245K, D250E, A272P, R284K, T286A, A288T, E297T, R307K  
402788Z 402788Z None NVP  V106M V35T, E36A, T39E, S48T, V90I, K122E, D123S, A158S, K173A, D177E, T200A, Q207E, V241I, V245Q, A272Q, L283I, V292I, I329L  
403272F 403272F None NVP  Y181C V35T, E36A, T39E, E40D, K49R, V60I, D121Y, K122E, E169D, D177E, I178M, G196E, T200I, Q207E, R211K, F214L, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V  
409924L 409924L None NVP  K103KN, Y188YC E6D, V35T, E40D, K49R, V60I, K122E, D123E, I135T, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, V245E, D250E, K275Q, K277R, T286A, E291D, I293V, P294T  
413282X 413282X None NVP  Y181C K11T, K20R, V21I, V35T, T39K, T69S, K122E, D123N, K173S, V179I, I202V, Q207A, V245M, E248N, T286A, E291D, V292I, I293V, P294T, E312D, V317I  
413433L 413433L None NVP   V35T, T39A, E40D, V60I, D121H, K122E, D123S, I135T, K173A, Q174K, Q207D, R211K, E248D, K249R, A272P, L283I, I293V, P294T, E297K, E312D, S322A Y318I, Y319M, D320T 
414210P 414210P None NVP  Y181C S3R, V21I, V35T, E40D, K49R, V60I, K104R, D121Y, K122E, Q174L, D177E, I178V, T200I, Q207G, R211K, V245T, A272S, I274V, L282C, T286A, I293V, A327V  
415189-B 415189-B None NVP  K103KN V35T, T39K, S48T, V60I, K122E, D123S, I135T, K173L, Q174K, D177E, V179I, E194D, T200A, Q207A, R211S, V245K, D250E, K275Q, T286A, E291D, V292I, I293V, E312D  
417659J 417659J None NVP  Y181YC, G190GA K11T, V35T, D123N, I135T, K173S, Q174K, D177E, V179I, Q207A, R211S, F214L, V245M, A272P, T286A, I293V, P294T, E312D, P321S, D324E  
428544C 428544C None NVP  V106A V35T, E44D, K49R, V60I, K122E, I135T, T165I, E169D, D177E, I202V, Q207A, R211K, F214L, D250E, S251C, A272P, K277R, L282C, L283I, R284K, I293V  
430066A 430066A None NVP  K103KN, V106VA, Y181YC K11T, K20R, V21I, V35T, T39R, V60I, K122E, D123N, K173A, D177E, V179I, T200I, I202V, Q207AS, R211S, L228LF, V245Q, E248N, A272P, T286A, E291D, V292I, I293V, P294T, E312DN  
458569M 458569M None NVP  K103N V35T, V60I, K122E, D123N, I135T, S162Y, K173S, Q174K, V179I, Q207E, R211K, V245E, D250E, S251H, T286A, E291D, V292I, I293V, P294V, A327V  
460471T 460471T None NVP   P4H, K11A, K20R, V21I, V35T, T39M, K122E, D123N, E138S, I142V, K173S, Q174K, D177E, V179I, T200E, I202V, Q207A, R211K, V245Q, E248D, A272P, T286A, E291D, I293V, P294T  
461597R 461597R None NVP   V35T, K49R, V60I, D121Y, K122E, A158S, D177E, I178M, T200V, Q207G, R211K, V245K, D250E, A272S, K277R, L282C, L283I, T286A, I293V, V317M  
467634E 467634E None NVP   K11KQ, V35T, E40D, K49R, V60I, K122E, D123G, D177E, I178M, T200E, E204K, Q207E, R211K, V245E, D250E, I257L, L260LI, A272AS, K281KR, L282C, T286AV, I293V  
476384H 476384H None NVP   K11T, K20R, V35T, T39G, K49R, K122E, D123S, K173S, Q174K, D177E, V179I, I202V, Q207A, R211S, V245Q, E248D, E291D, V292I, I293V, P294T, E312D  
476731T 476731T None NVP  Y181C V35T, E36D, T39K, V60I, D121Y, K122E, I135T, T165I, D177E, T200I, Q207E, R211K, V245K, D250E, A272P, K275R, K277R, Q278N, L282C, L283I, I293V, I329V P247E