Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Hosseinipour (2009)
Title The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 94
NumPts 94
Subtype C


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
7054 7054 D4T, 3TC NVP M184V K103N, Y181C T39E, S48T, K122E, D123G, I142V, E169EA, K173A, Q174K, D177E, T200A, Q207E, R211K, H221Y, V245Q  
7081 7081 D4T, 3TC NVP K70R, M184V, K219Q K103N, Y181C T39E, S48T, T69N, K122E, D123S, I135T, K173T, T200A, L228H, V245Q  
7135 7135 D4T, 3TC NVP M41L, D67DN, M184V, T215Y Y188L T39E, E44D, S48T, V60I, V118I, K122E, D123G, I135L, K166R, K173A, Q174R, D177E, I178M, V179VI, I195L, G196N, T200A, Q207E, L210S, R211K, D218DE, V245Q  
7241 7241 D4T, 3TC NVP M41L, D67DN, T69D, L74LV, M184V, L210W, T215Y, K219R K103N, K238T T39E, E44ED, V60I, V118I, K122E, D123N, I135LM, E138A, E169EA, F171Y, K173A, I195IT, T200A, I202V, Q207D, R211K, L228H, P243T, V245Q  
7294 7294 D4T, 3TC NVP M41L, M184V, T215Y K103S, G190A T39E, S48T, K122E, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q  
7336 7336 D4T, 3TC NVP M41L, D67N, T69D, M184V, L210W, T215Y A98G, V108VI, Y181C T39E, E44D, V118VI, K122E, D123N, S162C, K173T, Q174K, T200A, E203K, Q207E, R211K, H221Y, L228LH, V245M  
7344 7344 D4T, 3TC NVP A62V, K70E, V75T, Q151M, M184V K101E, Y181C, G190A T39E, E40K, S48T, K104R, K122E, D123N, K173T, Q174R, I178L, T200A, Q207E, R211K, F214L, L228H, V245K  
7448 7448 D4T, 3TC NVP M184V Y188Y*FL, G190GA T39E, S48T, V60I, K122E, D123G, K173A, Q174K, T200A, Q207E, V245Q  
7725 7725 D4T, 3TC NVP K65R, Q151M, M184V V179D, Y181C T39E, E53D, S68G, K103R, V118I, K122E, D123S, I135T, T139A, S162D, K173T, T200A, Q207A, R211K, F214L, K223KQ, V245Q  
7895 7895 D4T, 3TC NVP   T39E, E40ED, S48T, K122E, D123G, K173A, D177E, G196T, T200A, E203ED, E204Q, Q207E, V245Q  
7915 7915 D4T, 3TC NVP M41L, D67N, M184V, L210W, T215Y, K219N Y188L T39E, E44D, S48T, V118I, K122E, K173T, T200A, Q207E, H208Y, R211K, V245Q  
7934 7934 D4T, 3TC NVP M41L, D67N, M184V, T215Y, K219N Y181C, G190A T39E, E44D, S48T, V118I, K122E, D123N, S162D, K173AT, Q174K, D177E, T200A, E203D, Q207E, H208Y, R211K, H221Y, V245Q  
8015 8015 D4T, 3TC NVP D67N, K70R, M184V Y181C K122E, I135R, I142V, T165M, K173A, Q174K, D177E, I195L, G196M, T200A, I202V, Q207E, R211IK, D218DE, V245Q  
8080 8080 D4T, 3TC NVP M184V, T215F K103N, Y181C T39E, S48T, K122E, I135IT, K173A, D177E, T200A, I202V, Q207E, R211K, H221Y, V245K  
8131 8131 D4T, 3TC NVP D67G, K70R, L74I, V75S, M184V, T215F, K219E A98G, V108I, Y181C T39E, S48T, S68G, K122E, I135T, S162Y, K173T, V179I, G196E, T200A, E203K, Q207E, L210F, R211K, D218DE, K223KE, L228H, Q242H, V245HQ  
8211 8211 D4T, 3TC NVP K70KEGR, F116FY, Q151QKLM, M184MV G190GE T39E, S48T, K122E, D123NS, E138A, I142V, K166KR, K173I, Q174K, T200A, Q207A, R211K, F214FL, V245Q  
8261 8261 D4T, 3TC NVP A62V, K65R, K70R, V75I, F116Y, Q151M, K219E V106M, Y188C T39E, S48T, S68G, A98S, K122E, T139TA, A158S, K173A, Q174K, D177E, I178M, G196T, T200A, I202V, Q207K, H208HY, H221Y, E224D, P243PT, V245Q  
8269 8269 D4T, 3TC NVP A62V, K65R, V75I V106M, Y181C, G190A T39E, S48T, K122E, K173A, D177E, G196V, T200A, I202IV, E204K, Q207E, V245Q  
8295 8295 D4T, 3TC NVP D67N, K70R, M184V, L210W, T215Y, K219E Y181C, G190A T39E, V60I, V118VI, K122E, D123S, I135T, S162D, E169A, K173A, D177E, I178F, V179I, T200A, E203K, Q207E, H208Y, R211K, D218E, L228H, V245Q  
8345 8345 D4T, 3TC NVP D67G, K70R, M184V, K219E K103N, Y181C T39E, S48T, V60I, S68G, K122E, I135IT, K173T, Q174K, D177E, V179VI, T200EQ, E203K, Q207E, R211K, D218E, L228H, V245K  
8455 8455 D4T, 3TC NVP M184V K101KE, Y188L T39K, E40EK, K43E, S48T, D123E, E138A, Q197P, T200E, Q207KN, R211K, V245Q C38C* 
8503 8503 D4T, 3TC NVP K65R, T69~, K219R K101E, Y181C, G190A T39E, S48T, V60I, S68G, K122E, D123S, E138A, K173A, D177E, T200A, I202V, E204K, Q207A, L210S, R211K, F214L, H221Y, V245Q P157A 
8514 8514 D4T, 3TC NVP M41L, D67N, M184V, L210LW, T215F K101H, K103N, G190A T39E, S48T, V60I, K122E, D123S, I135T, K173T, D177DN, T200A, Q207E, D218DE, V245Q  
8566 8566 D4T, 3TC NVP   T39E, S48T, A98S, K122E, D123N, I135T, E138A, I142IV, K173A, D177G, T200A, Q207D, R211K, V245Q  
8588 8588 D4T, 3TC NVP M184V K103N T39E, S48T, K122A, D123N, I135M, K173A, T200A, Q207N, R211K, V245VM  
8699 8699 D4T, 3TC NVP M184V, T215Y K103N, Y181C T39E, S48T, K122E, D123GS, Q174K, D177E, T200A, Q207E, V241I, V245K  
8732 8732 D4T, 3TC NVP A62V, K65N, V75IT, K219R K103N, Y181C T39D, S68G, A98S, K122E, I132L, A158S, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q  
8760 8760 D4T, 3TC NVP K65R, T69~, K70R, V75I, F77L, F116Y, Q151M Y181I T39E, E53D, S68G, K122E, D123S, I132L, S162Q, K173T, T200A, Q207GR, V245EK P157A 
8770 8770 D4T, 3TC NVP D67N, K70R, M184V, T215F, K219Q Y188L T39E, S48T, K122E, D123S, I135T, I167V, K173A, Q174K, D177E, V179I, G196T, T200A, I202V, Q207E, R211RK, V245R  
8802 8802 D4T, 3TC NVP M184V, T215TNSY K101KE, Y181YC, M230ML W88WC, A98AS, D121DH, K122KE, D123X, E138EA, I142IV, S162SC, K173A, Q174KR, D177DG, I178IL, V179VI, G196GR, T200TA, E203EK, Q207AE, R211K, H221HY, L228LR, V245Q  
8821 8821 D4T, 3TC NVP D67N, M184V, T215Y K103N T39E, A98S, V118VI, K122E, D123S, I135IT, E138Q, S162C, K173A, Q174K, N175NY, D177E, I178IM, G196M, T200A, Q207E, H208HY, R211RK, V245T  
8895 8895 D4T, 3TC NVP A62V, K65R, V75I, F77L, F116Y, Q151M Y181C, G190A T39E, S48ST, S68G, T69I, V90I, V118I, K122E, D123N, R172K, K173T, D177DE, I178IL, T200A, E204K, Q207E, R211RK, F214L, K223Q, L228R, V245Q  
8934 8934 D4T, 3TC NVP F116Y, Q151M, M184V K101E, G190A T39E, S48T, K122E, D123G, S162C, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q  
8947 8947 D4T, 3TC NVP A62V, V75I, F77L, F116Y, Q151M, T215Y, K219Q K103N, Y181C T39D, S48T, S68G, T69TN, V111I, V118I, K122E, D123N, I142V, M164L, T165I, K173A, T200A, I202IV, Q207E, R211K, F214FL, V245Q  
8983 8983 D4T, 3TC NVP M41L, L74I, M184V, L210W, T215Y A98G, K103N, V108I T39E, E44D, S48T, S68SG, V118I, K122E, D123S, I135L, E138EG, I142T, K173AE, Q174R, D177E, I178M, G196D, T200A, E203K, Q207E, R211K, H221Y, V245Q  
8990 8990 D4T, 3TC NVP D67N, K70R, M184V, K219Q K101E, G190A, K238KT T39E, E53D, K122E, D123S, I135T, A158S, K173A, Q174K, D177E, I178M, G196K, T200E, Q207E, R211K, L228Q, V245Q  
9300 9300 D4T, 3TC NVP M184V, T215Y Y181C, G190A T39E, S48T, K49KR, K122E, D123S, A158S, K173T, V179VI, G196K, T200A, Q207E, R211K, K238R, V245Q  
9301 9301 D4T, 3TC NVP M184V, T215TN, K219KR K101E, G190S, M230MLRW, K238KT T39D, W88C, A98S, E138A, K173A, Q174AE, V179I, G196M, T200A, E203EK, Q207A, R211K, V245Q P133PT, I142IGSV, S156SL, N175NK, K201KN 
9306 9306 D4T, 3TC NVP A62V, D67N, K70E, V75T, Q151M, M184V Y181C, G190A T39E, E40K, S48T, K122E, I135M, A158S, T165I, K173A, D177E, G196T, T200A, Q207E, R211K, F214L, H221Y, V245Q Q182H 
9307 9307 D4T, 3TC NVP D67DG, K70KR, V75VM, F77FL, M184V, K219H V108I, Y181C T39E, S48T, T69TN, K82KR, K122E, D123G, T139I, K173A, D177E, T200A, Q207E, L228R, V245K  
9308 9308 D4T, 3TC NVP M41L, D67N, M184I, T215Y K103N, Y181V T39E, V90VI, K102R, K122E, T139I, K173T, Q174E, D177E, T200A, Q207G, R211K, D218E, V245Q  
9311 9311 D4T, 3TC NVP   T39E, S48T, K122E, D123DG, I142T, S162A, K173T, Q174A, T200A, E203D, Q207N, R211K, V245Q  
9314 9314 D4T, 3TC NVP M41L, M184V, T215Y K103N T39E, S48T, V60I, K122V, D123N, I135M, I178M, T200A, K238R, V245M  
9315 9315 D4T, 3TC NVP A62V, K65R, V75I, F116Y, Q151M, M184V Y181C T39E, S48T, S68G, K122E, D123N, K173T, Q174R, T200A, Q207E, R211K  
9321 9321 D4T, 3TC NVP   T39E, W88C, K122E, D123G, E138A, Q145C, K173A, Q174QK, T200A, Q207D, R211K, V245Q  
9326 9326 D4T, 3TC NVP A62AV, K65R, V75I, Q151M, M184V Y181I T39E, S48ST, S68G, K122E, I132L, K173T, Q174K, T200A, I202IV, Q207E, F214L, V245E  
9327 9327 D4T, 3TC NVP M41L, D67DG, K70R, M184V, T215Y Y181C T39E, V60I, T69N, K122E, D123NS, I135R, K173A, Q174K, T200A, E203K, Q207A, R211K, K223E, V245Q  
9334 9334 D4T, 3TC NVP M184V A98G, Y181C T39E, S48T, D86DN, V111VL, K122E, D123GS, S162SC, K173A, D177E, T200A, E203EV, Q207E, D218E, D237E, V245Q  
9335 9335 D4T, 3TC NVP   T39E, S48T, K122E, D123DG, I135V, K173A, Q174K, D177E, I178IL, G196K, T200A, Q207E, R211K, V245Q  
9340 9340 D4T, 3TC NVP L74LV, M184V Y181C T39A, S48T, A98S, K122E, A158AT, K173A, Q174K, T200A, Q207E, R211K, V245Q  
9342 9342 D4T, 3TC NVP K65R, Q151M K103N, Y181C T39E, S48T, S68G, V90VI, K122E, K173T, D177G, T200A, Q207A, R211K, F214FL, K223KQ, L228R, V245Q  
9344 9344 D4T, 3TC NVP M41L, D67N, T69TADN, M184V, L210LW, T215Y A98G, Y188L T39E, E44D, V60VI, L100LV, V118I, K122E, D123N, S162SDGN, K173A, Q174EK, D177G, G196V, T200A, Q207E, H208HY, R211RK, W212WLMR, D218DE  
9347 9347 D4T, 3TC NVP M41ML, L74LV, M184V, T215Y K103N, Y181C T39E, S48T, K122E, D123N, I135IT, K173AT, D177E, T200A, Q207E, R211K, H221Y, P243ST, V245KT  
9350 9350 D4T, 3TC NVP D67N, M184V, L210W, T215Y V108I, Y181C T39E, I47IF, V60I, K122E, D123S, I135R, S163T, K173A, D177E, I178L, T200K, E203K, Q207T, R211K, V245Q  
9355 9355 D4T, 3TC NVP M41L, D67N, M184V, L210W, T215Y V108I, Y181I E44D, S48T, V118I, K122E, D123S, I135L, S162D, K173A, D177E, V179I, G196E, T200AE, E203K, Q207E, H208Y, R211K, H221Y, V245Q  
9359 9359 D4T, 3TC NVP K65R, T69~, V75M, K219R V106M, Y181C T39E, S48T, E53D, K122E, D123G, K173A, D177E, T200A, Q207E, R211K, F214L, H221Y, V245Q P157A 
9360 9360 D4T, 3TC NVP M184V, T215TNSY A98G, Y181V T39D, S48T, K122E, I135ILM, K166R, K173T, I195IT, T200A, Q207AE, V245Q  
9363 9363 D4T, 3TC NVP M41L, D67N, L74I, V75S, M184V, L210W, T215Y, K219N V108VI, Y181I T39E, E44D, S48T, V118I, K122E, E138A, A158S, S162A, K166R, K173A, V179I, T200A, Q207A, R211K, D218E, V245Q  
9365 9365 D4T, 3TC NVP M41L, D67DN, M184V, L210W, T215Y K103N T39E, E44D, S48T, V118I, D121H, K122E, I135T, K173A, D177E, I178M, G196GE, T200A, Q207E, R211RK, V245Q  
9366 9366 D4T, 3TC NVP  K103KN T39E, S48T, K122E, D123DG, K173AT, D177E, T200A, Q207K, R211A, V245Q  
9369 9369 D4T, 3TC NVP D67N, K70R, M184V, T215F, K219Q A98G, K101E, G190A, P225H T39E, S48T, I94IL, K103R, K122E, D123N, K173T, Q174K, D177E, I195IM, T200A, Q207D, R211K, F214L, V245Q  
9371 9371 D4T, 3TC NVP K65R, T69~, Q151M, M184V Y181C, G190A T39E, S48T, E53D, K122E, D123G, I132L, K173A, D177E, I195IV, G196T, T200A, Q207E, R211K, V245Q  
9372 9372 D4T, 3TC NVP M184V K101HQ, G190A T39E, S48T, S68SG, K122E, D123G, K173A, D177E, I178V, V179I, T200A, E204K, Q207E, F214L, V245Q  
9373 9373 D4T, 3TC NVP A62V, K65R, V75I, F77L, F116Y, Q151M, M184V K103N, Y181C T39E, S68G, T69I, K122E, D123S, K173A, D177E, T200A, I202V, E204Q, Q207E, R211K, F214L, L228R, V245Q  
9378 9378 D4T, 3TC NVP A62V, V75I, M184V, K219KN Y181C, G190A T39E, K122E, D123G, K173A, D177E, E194D, T200K, I202IV, R211RK, H221HY, D237E, V245Q  
9379 9379 D4T, 3TC NVP M184V K103NS, G190GA T39K, K122E, K173T, Q174K, T200A, I202V, Q207E, R211RK, V245K  
9381 9381 D4T, 3TC NVP K65KR, M184V A98AG, Y188L T39E, S48T, T69TN, D121H, K122E, T139A, K173T, Q174K, D177E, T200A, Q207E, R211K, L228LR, D237DH, V245KQ  
9383 9383 D4T, 3TC NVP D67N, M184V, T215F K101KE, V108VI, Y181CFGV T39E, S48T, K122E, D123S, I135IT, K173T, Q174K, N175NY, T200E, Q207A, R211K, H221HY, V245Q  
9387 9387 D4T, 3TC NVP M184V, T215F K103S, G190A T39A, S48T, K122E, D123S, K173A, D177G, T200A, Q207E, R211K, P243T, V245Q  
9388 9388 D4T, 3TC NVP M41L, A62V, V75T, M184V, T215Y V108I, Y181C T39E, L109LI, K122E, I135R, S163T, T165I, K173A, Q174K, D177E, G196GE, T200A, Q207E, R211K, H221Y, V245Q  
9390 9390 D4T, 3TC NVP D67N, K70R, M184V, T215F, K219E Y181C, G190A T39E, S48T, K49R, E53D, K122E, D123S, I135V, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q  
9395 9395 D4T, 3TC NVP A62V, M184V V106M, Y181C T39E, S48T, K122E, D123G, K173T, T200A, E203EK, Q207E, R211K, V245Q  
9401 9401 D4T, 3TC NVP M41L, K65R V179D, Y181C T39E, E44D, K122E, S162C, K173T, D177E, I178L, T200A, Q207D, R211K, V245Q  
9402 9402 D4T, 3TC NVP M41L, D67N, K70R, M184V, T215F, K219W K101H, Y181I T39E, V60I, T69X, K122E, D123G, I135T, T139I, K173A, V179I, G196K, T200A, Q207E, H208Y, R211K, D218E, L228H, V245Q  
9405 9405 D4T, 3TC NVP K65R, Q151M, M184I Y181C T39D, S68G, K82KR, V90VI, K101KR, K122DE, D123G, K126KQ, I132L, S162Y, K173T, Q174K, T200A, Q207E, R211K, F214L, K223KE, V245Q  
9406 9406 D4T, 3TC NVP D67DN, K70KR, M184V K103KN, Y181C, G190GA T39E, S48ST, K102KR, V118M, K122E, D123S, T165IL, T200A, E203EK, Q207E, F214L, H221HY, V245Q  
9414 9414 D4T, 3TC NVP M184V, T215Y K101H, Y181C, G190A T39A, E44ED, S48T, V118VI, K122E, D123S, T139R, K173I, Q174K, D177G, G196E, T200A, Q207E, L210LS, R211RK, F214FL, D218DE, V245Q  
9417 9417 D4T, 3TC NVP D67N, K70R, M184V, K219Q A98AG, K103N S48T, V60I, K101KR, K122E, D123S, I135IT, K173A, Q174K, T200A, Q207E, F214L, V245L  
9419 9419 D4T, 3TC NVP M184V, T215Y V108VI, Y181C T39E, S48T, K122E, D123NS, I135IT, S162AD, K173A, G196V, T200A, Q207E, H221HY, V245Q  
9420 9420 D4T, 3TC NVP M184MIV K103RT, Y181C T39E, S48T, K122E, D123N, K173A, D177E, Q197K, T200E, Q207EG, R211K, H221HY, V245Q  
9422 9422 D4T, 3TC NVP D67N, K70R, M184V, T215F, K219Q K101E, Y188W T39E, K49R, E53D, I94L, K122E, D123G, S162Y, K173A, Q174K, D177E, I178M, T200A, Q207N, R211K, V245Q  
9424 9424 D4T, 3TC NVP K65R, K70KR, V75I, F77FL, F116Y, Q151M, M184I Y181C T39E, S48T, V60I, S68G, K122E, D123S, I132L, I135T, K173A, Q174K, D177E, I178M, T200A, E204D, R211K, H221Y, V245Q  
9430 9430 D4T, 3TC NVP M184V K101KHNQ, K103KNRS, V106M, F227L T39E, S48T, K122E, D123S, K173T, D177E, I178L, T200A, Q207R, R211K, V245Q  
9433 9433 D4T, 3TC NVP A62V, K65R, V75I, F77L, F116Y, Q151M, M184V Y181V T39E, S48ST, E53D, S68G, T69TI, K101Q, V118I, D121HY, K122E, I135T, K173A, Q174K, D177E, T200A, I202V, Q207D, L210F, R211K, F214L, V245Q  
9434 9434 D4T, 3TC NVP D67N, M184V, T215Y V108I, Y181C T39E, S48T, K122E, D123S, I135T, K173A, Q174K, D177E, T200A, Q207E, H221Y, V245Q  
9438 9438 D4T, 3TC NVP K65R, T69~, K70KN, K219R V108I, Y181C T39E, E40D, S48T, S68G, V90VI, K122E, D123N, K173A, Q174K, D177E, I178L, V179IT, T200A, K201KR, Q207E, R211K, H221Y, P243T, V245Q  
9443 9443 D4T, 3TC NVP D67N, M184V, T215Y K101E, G190A T39K, K43E, S48T, V60I, D123E, K173AT, D177E, T200A, Q207G, R211K, K238KR  
9446 9446 D4T, 3TC NVP M184MV K103N T39E, S48T, V90I, K122E, D123DG, I135IMT, S162H, K173IT, Q174K, D177E, I178IM, T200AE, E203ED, Q207E, R211KT, V245Q  
9449 9449 D4T, 3TC NVP M184V, T215TFIS K103N, G190A T39E, S48T, K122E, D123G, I135T, K173A, Q174K, D177E, T200EK, Q207A, R211K, V245Q  
9454 9454 D4T, 3TC NVP M184V, T215F V106M, V179D, M230L T39E, S48T, K103R, L109I, K122E, D123N, K173A, Q174R, T200A, I202IV, Q207R, R211E  
9455 9455 D4T, 3TC NVP M184V, T215Y K101E, G190A T39DE, S48T, K122E, D123S, S162C, K173T, Q174K, N175NY, T200A, Q207E, R211K, V245T  
9456 9456 D4T, 3TC NVP A62V, T69DN, F116Y, Q151M, M184V K103N, Y181C T39E, S48T, K102N, K122E, D123G, T165I, K173I, Q174K, Q197E, T200A, I202V, E204Q, Q207E, R211K, F214L, L228R, V245Q Q182H 
9457 9457 D4T, 3TC NVP D67N, M184V, L210W, T215Y A98G, K101E, V108I, Y181C T39E, E44ED, S48T, K49R, V118VI, K122E, D123S, I135R, K173A, D177E, V179VI, T200A, E203K, Q207D, H208Y, R211K, H221Y, V245Q  
9458 9458 D4T, 3TC NVP D67S, T69G, K70E, V75M, M184V, T215Y V108I, Y181C T39E, S48T, V118I, K122E, I135T, K173A, Q174K, D177E, T200A, Q207E, R211K, H221Y, V241M, V245Q