<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Ibe (2008)
Title Analysis of near full-length genomic sequences of drug-resistant HIV-1 spreading among therapy-naive individuals in Nagoya, Japan: amino acid mutations associated with viral replication activity.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 12
NumPts 12
Subtype B

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
117 117 None None   E6D, V35I, S68G, I135T, T139I, G196E, R211G, V245E, A272P, T286A, P294Q, K311R, G333E, Q334L, E344D, A371V, T377K, K390R, T403M, G436E, D460N, V467I, H483Y, L491S, L517V, K558R  
134 134 None None   E53ED, S68G, K122KQ, D123DE, D177E, G196E, R211G, V245E, A272P, V276I, L283LI, T286A, P294Q, Q334M, M357I, G359S, A371V, I375V, T377K, V381I, T403M, D460N, V467I, T470A, L491S, K512N, L517V, K558R  
194 194 None None   V60I, S68G, G196E, R211G, V245E, A272P, K281R, T286A, I293V, P294Q, K311R, G333E, Q334L, A371V, T377K, T403M, Y405H, D460N, V467I, L491S, L517V, K558R  
197 197 None None   V60I, S68G, G196E, R211G, V245E, A272P, K281R, T286A, I293V, P294Q, K311R, G333E, Q334L, A371V, T377K, T403M, Y405H, D460S, V467I, L491S, L517V, K558R  
227 227 None None   E6D, S68G, K102R, K122E, I135T, I142L, V179I, G196E, T200TI, I202IV, R211G, V245E, A272P, T286V, P294Q, G333E, Q334M, G359S, A371V, T377K, K390R, T403M, N447S, D460N, V467I, L491S, L517V  
285 285 None None N348I K103N V35I, K122E, I135L, S162C, G196E, Q197K, E204K, A272P, K277R, T286A, A288G, I293V, E297A, I326V, Q334L, R358K, V365I, K385R, K390R, T403M, N418NS, K527N, K558R  
329 329 None None  K103N V35I, K122E, I135L, S162C, G196E, Q197K, E203EK, A272P, K277R, A288G, I293V, E297A, I326V, Q334L, R358K, V365I, K385R, K390R, T403M, K527N, K558R  
398 398 None None  K103N V35I, K122E, I135L, S162C, V179VI, G196E, Q197K, A272P, K277R, A288G, I293V, E297A, I326V, Q334L, R358K, V365I, K385R, K390R, T403M, V435VA, K527N, K558R  
426 426 None None  V179D E6D, S68G, V106I, D123E, K166KR, G196E, R211G, F214L, V245E, A272P, K281R, T286A, I293V, P294Q, K311R, E312AV, G333E, Q334L, K366R, A371V, T377K, K390R, T403M, D460N, V467I, T470N, L491S, L517V  
436 436 None None   E6D, V35I, S68G, K82KR, T139L, G196E, T200I, R211G, V245E, A272P, T286A, I293V, P294Q, I309V, K311R, S322SA, G333E, Q334L, Y342F, M357V, A371V, I375V, T377K, K390R, T403M, G436E, D460N, V467I, H483Y, L491S, L517V, K558R  
472 472 None None  K103N V35I, E36D, K122E, D123E, I135L, S162C, G196E, Q197K, A272P, K277R, A288G, I293V, E297A, I326V, Q334L, R358K, V365I, K385R, K390R, T403M, V467I, I556V, K558R  
574 574 None None  K103N V35I, E36K, K122E, D123N, I135L, S162C, G196E, Q197K, A272P, K277R, T286A, A288G, I293V, E297A, I326V, Q334L, R358K, V365I, K385R, K390R, A400S, T403M, G436K, E449K, V466I, E523K, K527N, K558R Q464Q* 

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