<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Kassaye (2009)
Title Envelope coreceptor tropism, drug resistance, and viral evolution among subtype C HIV-1-infected individuals receiving nonsuppressive antiretroviral therapy.
Citation JAIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 51
NumPts 32
Subtype C


Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
TC-113 TC113_2003 Unknown Unknown   V35T, T39E, S48T, K122E, D123G, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, P243T, V245Q  
  TC113_2004 Unknown Unknown   V35T, T39E, S48T, K122E, D123G, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K  
TC-114 TC114_2003 Unknown Unknown   V35T, T39E, E40ED, S48T, K122E, D123G, I135T, S162A, K173A, D177E, T200A, Q207E, V245Q Q23QH, K238K*R 
  TC114_2004 Unknown Unknown V75VG  V35T, T39E, E40D, S48ST, V60VI, K122E, D123DG, I135T, E138EG, S162A, K173AT, D177E, T200A, Q207E, R211RK  
TC-117 TC117_2003 Unknown Unknown   V35T, E36A, T39E, E40D, S48T, V60I, K122E, D123N, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248N  
  TC117_2004 Unknown Unknown   V35T, E36A, T39E, E40ED, S48T, V60I, K122E, D123N, K173A, Q174K, D177E, T200A, Q207E, R211K  
TC-41 TC41_2003 DDI, AZT, 3TC NVP A62AV, K65R, K219KQ Y181YC V35T, T39E, K103R, K122E, D123S, I142T, K173T, Q174K, T200A, Q207E, R211K, F214L  
  TC41_2004 DDI, AZT, 3TC, D4T NVP A62V, K65R, K70R, V75I, F77L, Y115F, F116Y, Q151M, M184I, K219E Y181C V35T, T39E, S68G, V118I, K122E, D123S, I142T, K173T, Q174K, T200A, Q207E, R211K, F214L, D218E  
TC-47 TC47_2003 D4T, DDI NVP Q151QKLM K103KN, V106VM, Y181YC K20R, V35T, E36A, T39E, E40D, S48T, S68SG, K122E, S162A, K173A, Q174K, D177E, T200A, E203EK, Q207E, R211RK, F214FL, V245Q, E248D D123EGKR 
  TC47_2004 D4T, DDI, 3TC NVP F116Y, Q151M, M184V K103N, Y181C K20R, V35T, E36A, T39E, E40D, S48T, S68G, K122E, D123E, S162A, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, H221HY, Q242QH  
TC-52 TC52_2003 AZT, 3TC, D4T NVP M184V G190A V35M, T39E, S48T, K122E, D123N, I135M, K173T, Q174K, T200A, E203V, Q207E, V245Q  
  TC52_2004 AZT, 3TC, D4T, DDI NVP D67N, K70R, M184V, K219E  V35M, T39E, S48T, K122E, D123N, I135M, K173T, Q174K, T200A, Q207E  
TC-54 TC54_2003 AZT, 3TC, D4T NVP   V35T, E36A, T39E, E40D, S48T, K49KQ, E53D, K102R, V118I, K122E, D123NS, E138A, T139A, E169EQ, K173T, Q174K, G196E, T200A, Q207E, F214L, V245Q, E248D  
TC-63 TC63_2003 D4T, DDI, AZT, 3TC NVP, EFV  K103N V35T, T39E, S48T, K122E, D123E, K173AT, Q174QKR, D177E, I178IM, T200A, Q207E, R211K, P243Q, V245Q, A272P, K277R, E291D, V292I, I293V, A299X  
TC-68 TC68_2003 D4T, 3TC NVP  V106VM, K238KN K22R, V35T, E36A, T39E, E40D, S48ST, T69A, W88C, K122E, D123NS, S162H, K173A, D177E, E203Q, Q207E, R211K, V245Q H198HL 
  TC68_2004 D4T, 3TC, AZT NVP M184V  K22R, I31L, V35T, E36A, T39E, E40D, S48T, T69A, W88C, K122E, D123S, S162H, K173A, D177E, E203Q, Q207E, R211K  
TC102 TC102_2003 Unknown Unknown M184V  K32R, V35T, T39E, S48T, K122E, D123S, I135T, E138A, E169Q, K173T, Q174K, T200A, E203K, Q207E, R211K, F214L  
  TC102_2004 Unknown Unknown M184MV  K32R, V35T, T39E, S48T, K122E, D123N, I135IT, E138A, E169Q, K173T, Q174K, T200A, Q207DN, R211K, F214L  
TC12 TC12_2003 DDI, 3TC, Unknown, D4T Unknown, EFV, NVP M41L, M184V K103N V35R, E36A, T39E, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, I178L, I195L, G196V, T200A, Q207E, R211K, L228I, V245Q  
  TC12_2004 DDI, 3TC, Unknown, D4T Unknown, EFV, NVP M41L, M184V, T215Y K103N V35R, E36EA, T39DE, S48T, V60I, K122E, D123G, I135T, K173A, Q174K, D177E, I178L, Q197P, T200R, Q207E, R211K, L228I  
TC22 TC22_2003 Unknown Unknown M41L, V75I, T215Y L100I, K103N E28K, K32E, V35T, E36A, T39K, K43E, S48T, K122E, D123S, K173A, T200A, Q207E, Q242H K238K* 
TC53 TC53_2003 D4T, 3TC, AZT NVP, EFV   K32I, V35T, T39D, S48T, V60I, W88C, K122E, K173T, Q174R, V179I, T200A, Q207E, R211K, F214L A129~, F130~, T131~, I132~, P133~, S134~, I135~, N136~, N137~, E138~, T139~, P140~, G141~, I142~, R143~ 
TCDD-01 TCDD-01 AZT, 3TC, D4T NVP M184V  V35T, T39E, S48T, V60I, K122E, D123S, I135V, G141X, I142X, R143X, K173A, Q174K, D177E, I178L, T200A, Q207D, R211K  
TCDD-02 TCDD-02_1 AZT, 3TC, D4T None   V35T, E36EA, T39E, K122E, D123G, I142X, R143X, K173A, Q174R, D177E, I178IM, T200A, Q207D, R211K  
  TC02_2003 AZT, 3TC, D4T None M184V  K11Q, V35T, E36EA, T39E, S48ST, K122E, D123G, K173A, Q174R, T200A, Q207DE, R211K, F214FL, V245Q  
TCDD-04 TCDD-04 D4T, ABC NVP, EFV   V35T, E36A, T39D, S48T, K122E, G141X, I142X, R143X, Y144X, Q145X, D177E, T200A, Q207E, R211RK V60VIM, P170G, F171I, K173Y 
TCDD-05 TCDD-05_1 D4T, 3TC None M41L, M184V  V35T, T39E, S48T, E53D, K122E, D123S, A129X, F130X, T131X, I132X, P133X, S134X, I135X, N136X, N137X, E138X, T139X, P140X, G141X, I142X, R143X, T165I, K166N, E169T, K173R, Q174K, T200A, Q207D, R211K I159A, Q161T, S162I, S163P, M164S, I167N, L168E, F171G, R172I 
  TC05_2003 D4T, 3TC None M184V  V35T, T39E, S48T, E53ED, K122E, D123S, I135L, S162A, K173T, Q174R, T200A, Q207D, R211K, V245Q  
TCDD-08 TCDD-08_1 D4T, 3TC None M184V  V35K, E36A, T39E, S48T, V60I, K173T, D177E, V179VI, T200A, Q207E, F214FL  
  TC08_2003 D4T, 3TC None L74LV, M184V M230ML V8I, K20R, V35K, E36A, T39E, S48T, V60I, K103KR, K173T, D177E, T200A, Q207E, T240TR P97PA, K238KEGR 
  TC08_2004 D4T, 3TC EFV M184V, T215F V179D, M230L V8I, K20R, V35K, T39E, S48T, V60I, K103R, K173T, D177E, T200A, Q207E  
TCDD-12 TCDD-12 DDI, 3TC None   V35T, E36A, T39D, E40ED, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, Q197P, T200X, Q207E, R211K  
TCDD-13 TCDD-13_1 DDI, AZT, 3TC None   V35T, T39E, S48T, K122E, D123NS, S162SN, K173V, Q174K, D177E, T200A, Q207A  
  TC13_2003 DDI, AZT, 3TC None M184V  V35T, T39E, S48T, K49KE, K122E, D123S, E138A, K173V, Q174K, D177E, T200A, Q207A, P243T, V245Q Y144YC 
TCDD-19 TCDD-19_1 AZT, 3TC None M41ML, D67DN, K70KR, M184V, T215TFIS  V35T, T39A, K46Q, S48T, V60I, R83RK, V90VI, K122E, D123S, I135T, N137X, E138X, T139X, P140X, G141X, I142X, S163T, K166I, K173A, D177E, T200A, Q207E Q161N, S162E, M164P, T165G 
  TC19_2003 AZT, 3TC, DDI, D4T NVP, EFV M41L, L74V K103N, V106M V35T, T39AE, V60I, K122E, D123S, I135T, S162A, K173A, D177E, T200A, Q207E, V245Q, D250E  
TCDD-22 TCDD-22 AZT, 3TC, DDI NVP M41L, M184V, T215Y K103N K32E, V35T, E36A, T39K, K43E, S48T, K122E, D123S, K173A, T200A, Q207E  
TCDD-23 TC23_2003 DDC, AZT None D67G, T69T_T, K70R, K219Q  V35T, T39E, S48T, V60I, K64N, K103KR, V118I, K122E, D123S, E138A, T139A, K173T, Q174K, T200A, I202V, E203K, Q207E, R211K, F214L, D218E, L228HR, V245E, E248D  
TCDD-25 TCDD-25 D4T NVP, EFV   V35T, E36A, T39E, S48T, K64KR, K122E, K173A, Q174K, D177E, T200TA, Q207A, R211RK  
TCDD-27 TCDD-27 AZT, 3TC None M41L, D67DN, K70KR, M184V, T215Y A98AG V35T, E36A, T39D, S48ST, V60I, K122E, D123N, I135T, K173A, Q174K, D177E, T200A, L205LF, Q207E, R211K  
TCDD-28 TC28_2003 AZT, 3TC, D4T NVP D67N, K70R, M184V, T215V, K219Q Y181C V35T, T39E, S48T, V60I, T69N, K122E, D123G, I135T, E138A, I142V, I167IV, K173A, N175Y, G190X, T200A, I202V, Q207A, V245Q, D250E  
  TC28_2004 AZT, 3TC, D4T, TDF NVP D67N, K70R, T215F, K219Q K101E, Y181C, G190A V35T, T39E, S48T, V60I, T69N, K122E, D123G, I135T, E138A, I167V, K173A, Q174K, N175Y, T200A, I202V, Q207A, H221Y  
TCDD-29 TCDD-29 AZT, 3TC None D67N, K70R, M184V, K219Q  V35T, E36A, T39E, E42G, S48T, V118I, K122E, D123N, I135T, E138X, T139X, P140X, G141X, I142X, R143X, Y144X, P170T, K173I, Q174R, N175Y, V179VI, T200A, Q207E, R211K, F214L F171P, R172G 
TCDD-30 TCDD-30_1 AZT, 3TC None M184V  V35T, T39E, S48T, E53D, K122E, D123GS, K173T, D177DE, I178IL, I195K, T200A, Q207A, R211K  
  TC30_2003 AZT, 3TC, D4T NVP M41L, D67N, K70R, T215F, K219Q Y181C V35T, T39E, S48T, E53D, V60I, K122E, D123S, K173T, D177E, I178L, T200A, Q207A, R211K, L228R, V245Q  
TCDD-31 TC31_2003 3TC, D4T, DDI NVP, EFV M41L, D67N, L74V, T215Y K103N, Y181C, G190A S3C, E6D, V35T, T39E, K122E, D123S, I142V, S163I, T165L, K173T, Q174K, D177E, T200A, E203D, Q207E, H208Y, R211K, V245Q, E248D  
TCDD-33 TCDD-33 DDI, D4T, AZT, 3TC None   V35T, T39E, S48ST, V60I, K122E, D123GS, G141X, I142X, R143X, K166R, K173A, Q174R, D177E, I178IM, T200A, Q207E, R211K  
TCDD-35 TC35_2003 DDC, AZT, 3TC, D4T, DDI NVP M41L, D67N, K70R, Q151M, M184V, T215FY, K219E Y181C, G190A T27S, V35T, E36A, T39E, E53D, V60I, K122E, D123S, S162Y, K166R, K173A, Q174K, D177E, I178L, T200A, E203EK, Q207E, R211K, K223KE, L228H, V245Q R172I 
  TC35_2004 DDC, AZT, 3TC, D4T, DDI NVP M41L, A62V, K65R, K70R, V75T, Q151M, T215Y, K219E Y181C, G190A K20KR, T27S, V35T, E36A, T39E, E53D, S68G, K122E, D123S, S162Y, K166R, R172K, K173A, Q174K, D177E, I178L, T200A, E203K, Q207E, R211K, F214FL, D218DN, K223E, L228H  
TCDD-6 TC06_2003 DDI None   V21I, V35M, E36A, T39E, S48T, K122E, D123S, I135R, K173A, D177E, T200A, Q207E, V245Q  
  TC06_2004 DDI NVP   V21I, V35M, E36A, T39E, S48T, K122E, D123S, I135R, K173A, D177E, T200A, Q207E T131TA