<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Kassaye (2009)
Title Envelope coreceptor tropism, drug resistance, and viral evolution among subtype C HIV-1-infected individuals receiving nonsuppressive antiretroviral therapy.
Citation JAIDS
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 51
NumPts 32
Subtype C


Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
TC-113 TC113_2003 Unknown    I15V, L19I, M36I, R41K, H69K, L89M, I93L  
  TC113_2004 Unknown    I15V, L19I, M36I, R41K, H69K, L89M, I93L  
TC-114 TC114_2003 Unknown    I15V, L19I, M36I, R41K, D60E, L63P, H69K, V77VI, L89M, I93L  
  TC114_2004 Unknown    I15V, L19I, M36I, R41K, D60E, L63P, H69K, L89M, I93L  
TC-117 TC117_2003 Unknown    I15V, M36I, R41K, L63P, H69K, L89M, I93L  
  TC117_2004 Unknown    I15V, M36I, R41K, L63P, H69K, L89M, I93L  
TC-41 TC41_2003 None    W6WG, T12TP, I15V, L19LI, E35D, M36I, R41K, K45R, R57K, L63PS, H69K, L89M, I93L  
  TC41_2004 None    I15V, G17D, L19I, E35D, M36I, R41K, K45R, R57K, L63S, H69K, L89M, I93L  
TC-47 TC47_2003 None    I15V, L19IT, M36I, R41K, I62V, L63S, H69K, A71T, I72E, L89M, I93L  
  TC47_2004 None    I15V, L19T, M36I, R41K, I62V, L63S, H69K, A71T, I72E, I93L  
TC-52 TC52_2003 None    T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89M, I93L  
  TC52_2004 IDV 48   T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89M, I93L  
TC-54 TC54_2003 None    T12S, I15V, L19V, M36I, R41K, D60E, Q61QE, H69K, L89M, I93L  
TC-63 TC63_2003 None    T12S, I15V, L19I, M36I, R41K, L63S, H69K, L89M, I93L  
TC-68 TC68_2003 None    I15V, L19I, M36I, N37S, R41K, I64L, H69K, V82I, L89M, I93L  
  TC68_2004 NFV, LPV 17 I54L, L90LM L10LF I15V, L19I, K20T, E35DG, M36I, N37S, R41K, I64L, H69K, V82I, I85V, L89M, I93L  
TC102 TC102_2003 Unknown    T12S, I15V, L19I, E35D, M36I, R41K, K45R, D60E, H69K, L89M, I93L  
  TC102_2004 Unknown    T12S, I15V, L19I, E35D, M36I, R41K, K45R, D60E, H69K, V82VI, L89M, I93L  
TC12 TC12_2003 Unknown, IDV, APV 26   T12S, I15V, L19I, M36I, R41K, L63LI, H69K, I72IV, L89M, I93L  
  TC12_2004 Unknown, IDV, APV 26   I15V, L19I, M36I, R41K, H69K, L89M, I93L  
TC22 TC22_2003 Unknown  L90M  I15V, L19I, K20T, M36I, R41K, I62V, L63A, H69K, A71V, I93L  
TC53 TC53_2003 NFV   M36I, R41K, D60E, L63P, H69K, L89M, I93L  
TCDD-01 TCDD-01 NFV 22   T12S, I15V, L19I, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63I, E65D, H69K, V82I, L89M, I93L  
TCDD-02 TCDD-02_1 IDV, SQV 86   T12S, I15V, L19I, M36I, R41K, H69K, L89M, I93L  
  TC02_2003 IDV, SQV 199 L90M  T12S, I15V, L19I, K20MR, E35D, M36I, R41K, L63LP, H69K, T74A, L89M, I93L L5LV, W6WLMR, Q7QL, P9PL 
TCDD-04 TCDD-04 NFV, APV 38   T12S, I15V, L19I, M36I, R41K, L63P, H69K, I93L D25DN 
TCDD-05 TCDD-05_1 SQV 38 L90M  T12S, I15V, L19I, M36I, R41K, L63P, H69K, A71V, I93L  
  TC05_2003 SQV 147 L90M  T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, A71V, I93L W6W*, P9PR 
TCDD-08 TCDD-08_1 SQV 95   I15V, L19I, M36I, R41K, D60E, L63T, H69K, I72IT, T74S, L89M, I93L  
  TC08_2003 SQV 210   I15V, L19I, M36I, R41K, D60E, L63T, H69K, I72T, T74S, L89M, I93L  
  TC08_2004 SQV 239   I15V, L19I, M36I, R41K, D60E, L63T, H69K, I72T, T74S, L89M, I93L  
TCDD-12 TCDD-12 None    T12TS, I15V, L19LI, M36I, R41K, L63LAPV, H69K, V82I, L89LM, I93L L24L* 
TCDD-13 TCDD-13_1
Consensus 
SQV 69   T12TS, I15V, L19LI, M36I, R41K, L63LAPV, H69K, V82I, L89LM, I93L L24L* 
  TC13_2003 SQV, NFV 178   I15V, L19LI, M36I, R41K, L63V, H69K, V82I, I93L  
TCDD-19 TCDD-19_1 None    I13V, I15IV, L19I, M36I, R41K, H69K, T74S, L89M, I93L  
  TC19_2003 IDV, RTV 26   I13V, I15V, L19I, M36I, R41K, H69K, T74S, L89M, I93L  
TCDD-22 TCDD-22 SQV, IDV 17   I15V, L19I, M36I, R41K, L63A, H69K, I93L  
TCDD-23 TC23_2003 SQV 304 L90M  I15V, L19I, K20M, M36I, R41K, D60E, L63P, H69Q, V82I, L89M, I93L  
TCDD-25 TCDD-25 IDV, SQV, RTV 49   T12S, I15V, L19I, M36I, L63LP, H69K, L89LM, I93L  
TCDD-27 TCDD-27 SQV 149   T12S, I13V, I15V, G16E, L19I, K20R, M36I, R41K, H69K, I93L  
TCDD-28 TC28_2003 SQV 361 L90M G73S I15V, L19I, K20I, M36I, L63P, H69K, A71V, I93L  
  TC28_2004 SQV, LPV 378 M46I, I84V, L90M G73S I15V, L19I, K20I, M36I, L63P, H69K, A71V, I93L  
TCDD-29 TCDD-29 SQV 140 L90M  I15V, G16E, K20KR, E21EK, E35D, M36I, P39S, R41K, K45R, D60E, L63P, H69K, A71AV, L89M, I93L, F99X  
TCDD-30 TCDD-30_1 NFV, IDV 14   L10I, T12A, I15V, L19I, E35D, M36I, N37ND, R41K, H69KQ, L89M, I93IL  
  TC30_2003 NFV, IDV 99 I54V, I84V  L10I, T12A, I15V, L19I, K20KR, E35D, M36I, R41K, L63P, H69Q, L89M, I93L  
TCDD-31 TC31_2003 SQV, APV, IDV, LPV 198 M46MI, L76V V32VG, I47IM D60DE, L63P, H69K, T74A, I85V, L89M, I93L R41R*K 
TCDD-33 TCDD-33 IDV 135   T12S, I15IV, L19I, K20R, M36I, R41K, H69K, L89M, I93L  
TCDD-35 TC35_2003 NFV, IDV 143   T12S, I15V, L19I, K20I, M36I, R41K, D60E, Q61E, L63P, H69K, I93L  
  TC35_2004 NFV, IDV 143  I54IF T12S, I13IL, I15V, L19I, M36I, R41K, D60E, Q61E, L63P, H69K, I93L  
TCDD-6 TC06_2003 None    T12S, K14KR, I15V, L19IT, M36V, R41K, H69K, L89M, I93L  
  TC06_2004 None    T12S, I15V, L19T, M36V, R41K, H69K, L89M, I93L