<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author van Hal (2009)
Title HIV-1 integrase polymorphisms are associated with prior antiretroviral drug exposure.
Citation Retrovirology
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 133
NumPts 133
Subtype B, D, K, A

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Page 1   from Isolate 1 to Isolate 100 from Total 133 Clinical IN Isolates

SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
W1 W1 None    E11D, V31I, T124N, T125V, T206S Q285P 
W10 W10 None    K14R, V32I, L45I, M50I, V201I, T206S, D256E  
W100 W100 None    D6N, S17N, L101I, K111T, S119P, I135V, D256E S283G 
W11 W11 None    E11D, V31I, M50L, I72V, L101I, I204V, T206S, A265V  
W12 W12 None    E11D, S24N, S57C, L101I, S119T, T124A, V201I, K211Q, D232E, L234V, D253E  
W13 W13 None    E11D, L28I, V37I, S39C, L101I, G163E, G193D, K211R, D279G  
W14 W14 None    E10D, N27G, V31I, I72V, L101I, I135V, G163E, R166K, R231K, D232N E152K 
W15 W15 None    V31I, S57C, I72V, L101I, S119G, T122I, T124A, K188R, G193E, V201I, T206S, K211R, R231K, A265V E152K 
W16 W16 None    E11D, E13D, L101I, K111T, I113V, T122I, T124A, V201I, T206S, D232E, D253H, D256E, D279G S283G 
W17 W17 None    V31I, V201I, D232E  
W18 W18 None    E11D, S24N, D25E, T112I, S119P, T125A, K136Q, V201I, L234I S283G 
W19 W19 None    E11D, S24N, D25E, V31I, S57C, G70E, I72V, L101I, T112I, S119P, T125A, K136Q, V176L, G193E, V201I, T206S, L234I, S255T S283G 
W2 W2 None    S24D, V31I, S57C, G70E, I72V, L101I, S119R, T125V, V176L, G193E, V201I, T206S, K215N, S230N S283G 
W20 W20 None    E11D, M50I, T122I, T124N, G193E, A265V  
W21 W21 None    V31I, L101I, S119G, T122I, V201I  
W22 W22 None    E11D, S24N, V32I, S39C, M50L, L101I, S119G, T124N, I135V, K136N, V201I, A205S, T206S, D253E, N254K  
W23 W23 None    E11D, A23V, L45Q, K188R, V201I, T206S, D232E, A265V  
W24 W24 None    S24N, V31I, M50I, I72V, T112A, K156N, K211R  
W25 W25 None    E11D, D25E, V31I, L101I, K111T, T112V, T122I, D279G  
W26 W26 None    L101I, T112I, T122I, T124N, V201I, A205S, N222H  
W28 W28 None    L101I, V201I  
W29 W29 None    D55G, T124A, I204V  
W3 W3 None    E11D, S17N, S24D, D25E, S39C, V77A, L101I, S119T, V201I, S230N  
W30 W30 None    D6N, L101I, I113L, I257V, R269K, D279G  
W31 W31 None    S17N, A91S, L101V, T124A, R166K, I204V, K215N, R231K, D232N  
W32 W32 None    K7Q, I72V, I113V, T124A  
W33 W33 None    K7Q, I113V, T124A, I257V  
W34 W34 None    K7Q, T124A, V250I  
W35 W35 None    K7Q, V37I, T124A E152K 
W36 W36 None    K7Q, D55G, A91T, T124A, T206S, I208L, K215N, I217V, R231K, D232N  
W37 W37 None    I72V, I113V, T124A, L234V  
W38 W38 None    V31I, I72V, L101I, T112I, S119G, T122I, T124A, T125S, G193E, V201I, L234V, R269K, D278N  
W39 W39 None    V31I, I72V, L101I, K111T, T122I, T124A, G193E R166G 
W4 W4 None    E11D, A91T, S119R, T125A, G193E, I203M, K240R, D256E  
W40 W40 None    S17N, V31I, V77A, T124A, G193E, I203M, K211R, S230N, S255T  
W41 W41 None    V31I, G193E, D256E D286N 
W42 W42 None    E11D, V31I, G193E, I208L, D278A S283G 
W43 W43 None    E11D, V31I, T124N, T125V, V176L, G193D Q285P 
W44 W44 None    D6E, E10D, A23V, S39C, L101I, S119P, T122I, V201I  
W45 W45 None    E11D, S24N, D25E, V31I, S57C, G70E, I72V, L101I, T112I, S119P, T125A, K136Q, V176L, G193E, V201I, T206S, L234I, S255T S283G 
W46 W46 None    E11D, S17N, S24D, D25E, S39C, V77A, L101I, S119T, V201I, D232E, L234I, D253E  
W47 W47 None    E11D, M50L, A91T, S119R, T125A, G193E, I203M, K240R, D256E  
W48 W48 None    R20K, I72V, L101I, T112V, T124Q, I135V, F181Y, G193D, S230G, R231K  
W49 W49 None    K156R, S195C, K215N, S230N, D278A S283G, D288N 
W5 W5 None    R20K, I72V, L101I, T112V, T124Q, I135V, F181Y, G193D  
W50 W50 None    S17N, S39C, L74I, T112V, K211R S283G 
W51 W51 None    S17N, S119R, T125A, G163E, H171Q, S195C, V250I  
W52 W52 None    S17N, S39C, K71Q, L101I, T112I, S119R, T122V, T124N, T125A, T206S, L234V  
W53 W53 None    E11D, A21T, M50T, V201I, K240R, V250I, Q252K, D253E, A265V, D279G  
W54 W54 None    E11D, S24N, V31I, L45I, L101I, T112I, I113L, T122I, T124N, V201I, T206S  
W55 W55 None    E10D, E13D, V31I, S39N, S119T, T124A, T125S, K188R, G193E, V201I, A265V  
W56 W56 None    K14R, V32I, L45I, M50I, V201I, T206S  
W57 W57 None    E11D, V31I, M50L, I72V, L101I, I204V, T206S  
W58 W58 None   L74M E11D, S24N, S57C, L101I, S119T, T124A, V201I, K211Q, D232E, L234I, D253E  
W59 W59 None    S39C, L74I, S119P, T122I, T125A, V176L, Q216H  
W6 W6 None    K156R, S195C, K215N, S230N  
W60 W60 None    E11D, L28I, V37I, S39C, G163E, G193D, K211R, D279G  
W61 W61 None    E11D, A21T, S39C, M50I, V176L  
W62 W62 None    E10D, N27G, V31I, I72V, L101I, I135V, G163E, R166K, V201I, S230G, R231K, D232N, D279G E152K 
W63 W63 None    S17N, V31I, S57C, I72V, L101I, S119G, T122I, T124A, K188R, G193E, V201I, T206S, K211R, R231K, A265V E152K 
W64 W64 None    E11D, E13D, L74I, L101I, K111T, I113V, T122I, T124A, V201I, T206S, D232E, D253H, D256E, D279G Q285P 
W65 W65 None    V31I, V201I, D232E R284G 
W66 W66 None    E11D, S24N, D25E, V31I, S57C, G70E, I72V, L101I, T112I, S119P, T125A, K136Q, V176L, G193E, V201I, T206S, L234I, S255T S283G 
W67 W67 None    E11D, S24N, D25E, T112I, S119P, T125A, K136Q, V201I, L234I  
W68 W68 None    E11D, M50I, T122I, T124N, A265V  
W69 W69 None    V31I, L101I, S119G, T122I, V201I, A265V  
W7 W7 None    S17N, S39C, L74I, T112V, K211R  
W70 W70 None    E11D, S24N, V32I, S39C, M50L, L101I, S119G, T124N, I135V, K136N, V201I, A205S, T206S, N254K  
W71 W71 None    K14R, R20K, S39C, I113V, K173R, V201I, T206S  
W72 W72 None    E11D, A23T, L45Q, K188R, V201I, T206S, D232E, A265V  
W73 W73 None    E11D, S24N, V31I, M50I, I72V, T112A, K156N, K211R  
W74 W74 None    E11D, D25E, V31I, L101I, K111T, T112V, T122I  
W75 W75 None   L74M L101I, T112I, T122I, T124N, V201I, A205S, N222H  
W76 W76 None    E10D, V31I, M50I, I72V, T112A, T124A, V201I, A265V  
W77 W77 None    E10D, I72V, T112A, T124A, V201I  
W78 W78 None    D55G, I72V, T112A, V201I  
W79 W79 None    S24N, I72V, T112A  
W8 W8 None    S17N, S119R, T125A, G163E, H171Q, S195C  
W80 W80 None    I72V, S81G, S119G, T122I, T125A, V201I S283N, Q285R 
W81 W81 None    S17N, I72V, S119G, T122I, T125A, V201I S283N, Q285R 
W82 W82 None    E10D, K14R, I72V, S119G, T122I, T125A, M154I, V201I R284G, Q285R 
W83 W83 None   V151I E11D, V31I, I72V, S119G, T122V, G134E, V250I R284G 
W84 W84 None   V151I E11D, S81G, S119G, T122V, G134E, Q216H R284G 
W85 W85 None    E11D, S119P, R166K, L234I, A265V Q285P 
W86 W86 None    S119T, R166K, D232E, L234V  
W87 W87 None    S119P, D232E, L234I, V250I  
W88 W88 None    T122I, T124N, A265V  
W89 W89 None    E96G, T122I, T124N, A265V  
W9 W9 None    S17N, S39C, K71Q, L101I, T112I, S119R, T122V, T124N, T125A, T206S, L234V, I268L  
W90 W90 None    E11D, V31I, I72V, L101I, S119G, R166K Q285R 
W91 W91 None    E11D, L101I, S119G, T122I, R166K R284G 
W92 W92 None    S17N, I72V, T122I, T124A, R166K, V201I, V250I, A265V  
W93 W93 None    S17N, I72V, T124A, R166K, A265V  
W94 W94 None    I72V, A265V  
W95 W95 None    I72V, V201I, D253E, A265V  
W96 W96 None   T97A I72V, A265V  
W97 W97 None    V31I, T206S  
W98 W98 None   T97A V31I, T124A, T206S  
W99 W99 None    E11D, I72V, T206S, A265V  

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