<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Nukoolkarn (2004)
Title Sequence variability of the HIV type 1 protease gene in Thai patients experienced with antiretroviral therapy.
Citation ARHR
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 10
NumPts 10
Subtype CRF01_AE, B, U


Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
220 220
Consensus 
RTV, IDV  I54V, V82A G48I, F53L, L89V L10I, I13V, K20I, E35D, M36I, N37D, R41K, L63P, H69K, A71V  
  clone: 220-1 RTV, IDV  I54V, V82A G48I, F53L, L89V L10I, I13V, K20I, E35D, M36I, N37D, R41K, L63P, H69K, A71V  
  clone: 220-2 RTV, IDV  G48M, I54V, V82A F53L L10I, I13A, K20I, E35D, M36I, R41K, I66F, H69K, L89I  
  clone: 220-3 RTV, IDV  G48M, I54V, V82A F53L L10I, I13A, K20I, E35D, M36I, R41K, I66F, H69K, L89I  
  clone: 220-5 RTV, IDV  I54V, V82A G48I, F53L, L89V L10I, I13V, K20I, E35D, M36I, N37D, R41K, L63P, H69K, A71V  
238 238
Consensus 
LPV  L90M  L10I, I13V, E35D, M36I, R41K, L63P, H69K, T74S, L89M  
  clone: 238-1 LPV  L90M  L10I, I13V, E35D, M36I, R41K, R57G, L63P, H69K, T74S, L89M  
  clone: 238-12 LPV  L90M  L10T, I13V, E35D, M36I, R41K, L63P, H69K, T74S, L89M  
  clone: 238-13 LPV  L90M  L10I, I13V, E35D, M36I, R41K, L63P, H69K, T74S, L89M G78E 
  clone: 238-2 LPV  L90M  L10I, I13V, E35D, M36I, R41K, L63P, H69K, T74S, L89M  
  clone: 238-5 LPV  L90M  L10I, I13V, E35D, M36I, R41K, L63P, H69K, T74S, L89M  
  clone: 238-6 LPV  L90M  L10I, I13V, E35D, M36I, R41K, L63P, H69K, T74S, L89M  
  clone: 238-7 LPV  L90M I47M L10I, I13V, E35D, M36I, R41K, L63P, H69K, T74S, L89M  
  clone: 238-8 LPV  L90M  L10I, I13V, E35D, M36I, R41K, L63P, H69K, T74S, L89M  
245 245
Consensus 
SQV, RTV, IDV  I54V, V82F L33I L10I, I13V, E35D, M36I, R41K, L63H, H69K, L89M  
  clone: 245-1 SQV, RTV, IDV  I54V, V82F L33I L10I, I13V, I15M, E35D, M36I, R41K, L63H, H69K, L89M  
  clone: 245-11 SQV, RTV, IDV  I54V, V82F L33I L10I, I13V, E35D, M36I, R41K, L63H, H69K, L89M  
  clone: 245-2 SQV, RTV, IDV  I54V, V82F  L10I, I13V, E35D, M36I, R41K, L63H, H69K, L89M  
  clone: 245-3 SQV, RTV, IDV  I54V, V82F L33I L10I, I13V, E35D, M36I, L63H, H69K, L89I  
  clone: 245-5 SQV, RTV, IDV  I54V, V82F L33I L10I, I13V, E35D, M36I, R41K, L63H, H69K, L89M  
  clone: 245-7 SQV, RTV, IDV  G48M, I54V, V82F  L10T, I13V, E35D, M36I, R41K, H69K, I72T, L89M  
267 267
Consensus 
RTV, IDV  M46I  L63T, I72T, L89M  
  clone: 267-1 RTV, IDV  L90M  L10I, I13V, E35D, M36I, R41N, L63P, H69K, T74S, L89M  
  clone: 267-2 RTV, IDV  M46I, I54V, V82A  L63T, I72T, L89M  
  clone: 267-3 RTV, IDV  M46I, L76V  L63T, K70E, I72T, L89M  
  clone: 267-4 RTV, IDV  M46I L10F L63T, I72T, L89M  
  clone: 267-5 RTV, IDV  M46I, L76V  L63T, I72T, L89M  
  clone: 267-7 RTV, IDV  M46I, L76V  W6R, L63T, I72T, L89M  
  clone: 267-8 RTV, IDV  M46I, I54V, V82A  L63T, I72T, L89M  
268 268
Consensus 
RTV, IDV  L90M Q58E, G73S E35D, M36I, R57K, I62V, L63P, A71V, V82I, I93L  
  clone: 268-1 RTV, IDV  L90M Q58E, G73S E35D, M36I, R57K, I62V, L63P, A71V, V82I, I93L  
  clone: 268-10 RTV, IDV  L90M Q58E L10I, E35D, M36I, R57K, I62V, L63P, V82I, I93L  
  clone: 268-2 RTV, IDV  L90M Q58E E35D, M36I, R57K, I62V, L63P, V82I, I93L  
  clone: 268-4 RTV, IDV  L90M G73S E35D, I62V, L63P, A71V, V82I, I93L  
  clone: 268-6 RTV, IDV  L90M V11I, Q58E, G73S E35D, M36I, R57K, I62V, L63P, A71V, V82I, I93L  
  clone: 268-7 RTV, IDV  L90M Q58E, G73S L19V, E35D, M36I, R57K, I62V, L63P, A71V, V82I, I93L  
  clone: 268-8 RTV, IDV  L90M Q58E, G73S K20R, E35D, M36I, R57K, I62V, L63P, A71V, V82I, I93L  
  clone: 268-9 RTV, IDV  L90M Q58E L10I, E35D, M36I, R57K, I62V, L63P, H69Q, V82I, I93L  
276 276
Consensus 
RTV, IDV    I13V, E35D, M36I, R41K, H69K, V82I, L89M  
  clone: 276-10 RTV, IDV    I13V, E35D, M36I, R41K, H69K, V82I, L89M  
  clone: 276-2 RTV, IDV    I13V, E35D, M36I, R41K, H69K, V82I, L89M  
  clone: 276-4 RTV, IDV    Q7R, I13V, E35D, M36I, R41K, K45R, H69K, V82I, L89M  
  clone: 276-5 RTV, IDV    I13V, E35D, M36I, R41K, H69K, V82I, L89M  
  clone: 276-6 RTV, IDV    I13V, E35D, M36I, R41K, H69K, V82I, L89M  
  clone: 276-8 RTV, IDV    I13V, E35D, M36I, R41K, H69K, V82I, L89M  
  clone: 276-9 RTV, IDV    I13V, E35D, M36I, R41K, H69K, V82I, L89M  
278 278
Consensus 
RTV, IDV  G48V, I54T, V82A Q58E L10I, K20R, E35D, M36I, Q61N, L63E, H69K, T74S, L89M  
  clone: 278-1 RTV, IDV  G48V, I54T, V82A Q58E L10I, K20R, E35D, M36I, Q61N, L63E, H69K, T74S, L89M  
  clone: 278-10 RTV, IDV  G48V, I54T, V82A Q58E L10I, K20R, E35D, M36I, Q61N, L63E, H69K, T74S, L89M  
  clone: 278-2 RTV, IDV  G48V, I54T, V82A Q58E L10I, K20R, E35D, M36I, Q61N, L63E, H69K, T74S, L89M  
  clone: 278-3 RTV, IDV  G48V, I54T, V82A Q58E L10I, K20R, E35D, M36I, Q61N, L63E, H69K, T74S, L89M  
  clone: 278-4 RTV, IDV  G48V, I54T, V82A Q58E L10I, K20R, E35D, M36I, Q61N, L63E, H69K, T74S, L89M  
  clone: 278-6 RTV, IDV  G48V, I54T, V82A  L10I, K20R, E35D, M36I, Q61N, L63E, C67Y, H69R, T74S, L89M  
  clone: 278-8 RTV, IDV  G48V, I54T, V82A F53L L10V, K20R, E35D, M36I, Q61D, L63Q, I66F, H69K, L89M R41G 
  clone: 278-9 RTV, IDV  G48V, I54T, V82A Q58E L10I, K20R, E35D, M36I, Q61N, L63E, H69K, T74S, L89M  
296 296
Consensus 
None  N88S L10F I13V, K20V, E35D, M36I, R41K, I62V, I64V, H69K, K70R, L89M  
  clone: 296-1 None  N88S L10F I13V, K20V, E35D, M36I, I62V, I64V, H69K, K70R, L89M  
  clone: 296-12 None  N88S L10F I13V, K20V, E35D, M36I, R41K, I62V, I64V, H69K, K70R, L89M  
  clone: 296-3 None  N88S L10F I13V, K20V, E35D, M36I, R41K, I62V, I64V, H69K, K70R, L89M  
321 321
Consensus 
NFV  L90M  I13V, K20I, E35D, M36I, R41K, I64V, H69K, L89M  
  clone: 321-1 NFV  L90M  I13V, K20I, E35D, M36I, R41K, I64V, H69K, L89M  
  clone: 321-10 NFV  L90M G48R I13V, K20I, E35D, M36I, R41K, I64V, H69K, L89M  
  clone: 321-2 NFV  L90M  I13V, K20I, E35D, M36I, R41K, I64V, H69K, L89M  
  clone: 321-3 NFV  L90M  I13V, K20I, E35D, M36I, R41K, L63P, I64V, H69K, L89M, T91P  
  clone: 321-9 NFV  L90M  I13V, K20I, E35D, M36I, R41K, I64V, H69K, L89M L5P 
74 74
Consensus 
RTV  I54V, V82A L33F, N83D L10I, I13V, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89M  
  clone: 74-1 RTV  I54V, V82A L33F, N83D L10I, I13V, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, I72V, L89M  
  clone: 74-10 RTV  I54V, V82A L33F, I47M, N83D L10I, I13V, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89M  
  clone: 74-2 RTV  I54V, V82A L33F, N83D L10I, I13V, K20R, E35D, M36V, R41K, D60E, Q61D, L63T, C67Y, H69K, L89M  
  clone: 74-3 RTV  I54V, V82A L33F, N83D L10I, I13V, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89M, I93V  
  clone: 74-4 RTV  I54V, V82A L33F, N83D L10I, I13V, A22T, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89M  
  clone: 74-5 RTV  I54V, V82A L33F, N83D L10I, I13V, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89M  
  clone: 74-6 RTV  I54V, V82A L33F, N83D L10I, I13V, K20R, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89M  
  clone: 74-7 RTV  I54V, V82A L33F, N83D L10I, I13V, K20R, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89M  
  clone: 74-8 RTV  I54V, V82A L33F, N83D L10I, I13V, K20R, A22V, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89M  
  clone: 74-9 RTV  I54V, V82A L33F, N83D L10I, I13V, K20R, E35D, M36I, N37D, R41K, D60E, Q61D, L63T, C67Y, H69K, I72V, L89M