Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Gody (2008)
Title High prevalence of antiretroviral drug resistance mutations in HIV-1 non-B subtype strains from African children receiving antiretroviral therapy regimen according to the 2006 revised WHO recommendations.
Citation JAIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 19
NumPts 19
Subtype CRF11_cpx, A, CRF02_AG, CRF01_AE, J, G + Unknown, A + J, CRF06_cpx


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
Pt029 Pt029 D4T, 3TC NVP M184V K103N, Y181C K49R, V60I, K122E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K S191F 
Pt030 Pt030 D4T, 3TC NVP M184V A98G, Y181C K20R, V35T, T39N, K49KR, V60I, K122E, I135T, T139R, I142V, K173T, D177E, T200A, Q207A, R211K, F214FL, V245M, A272P, T286A, E291D, V292I, I293V, E297A, E312D  
Pt032 Pt032 D4T, 3TC NVP M41L, M184V, T215F  V90I, K122E, D123S, I135T, S162A, F171Y, K173A, Q174K, D177E, I178M, T200A, Q207E  
Pt041 Pt041 D4T, 3TC NVP M41L, M184V Y181C, G190A K49R, V60I, D121H, K122E, I135T, K173A, Q174K, D177E, I178L, T200A, Q207A, R211S, K238R K101D 
Pt045 Pt045 D4T, 3TC NVP K65KR, V75I, M184V Y181C V8I, K11T, V35T, T39R, K43E, S68G, K101R, D121H, K122E, D123S, I132L, F171Y, K173A, Q174K, I202V, Q207A, R211S, H221Y, V245E, K275KR, T286A, A288T, E291D, V292I, I293V, P294T, E312T, I326V  
Pt046 Pt046 D4T, 3TC NVP M184V K103N K43R, K49R, V60I, K122E, D123N, I135T, S162C, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K  
Pt047 Pt047 D4T, 3TC NVP K65KR K101E, Y181C, G190A K11AT, V35L, S68SG, S105SA, D121HY, K122E, I135IV, K173A, Q174K, D177E, G196E, Q207A, R211N, L228LR, V245Q, E248DN, D250DE, K281R, T286A, E291D, I293V  
Pt049 Pt049 D4T, 3TC, AZT NVP M184V K101E, G190A D121H, K122E, D123S, I142T, K173A, Q174K, D177E, I202V, Q207A, R211S  
Pt056 Pt056 AZT, 3TC None M184V  K122E, D123S, I135V, I142V, K173T, D177E, I178L, T200E, I202V, Q207K  
Pt065 Pt065 AZT, 3TC None M184V  K43R, K49R, V118I, K122E, D123N, I135T, T139M, S162C, Q174D, D177E, T200K, Q207E  
Pt078 Pt078 D4T, 3TC NVP D67N, M184V K103N, Y181C D121H, K122E, D123S, K173T, Q174K, D177E, T200E, I202V, Q207G, R211K, H221Y  
Pt083 Pt083 D4T, 3TC NVP M184V K103N, V108I, Y181C V90I, V106I, K122P, T139K, S162C, K173T, Q174K, D177E, I178L, T200Q, Q207E, R211K  
Pt089 Pt089 D4T, 3TC NVP T215D K103T, Y181C T69P, K122E, D123S, K173A, Q174K, D177E, T200K, I202V, Q207E, R211K  
Pt171 Pt171 D4T, 3TC EFV   K49R, V60I, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K  
Pt176 Pt176 D4T, 3TC None   K122E, D123S, I135T, T165I, K173T, T200K, I202V, Q207E, R211K  
Pt195 Pt195 D4T, 3TC NVP   V60I, K122E, D123K, K173S, Q174R, D177E, T200A, Q207D, R211K  
Pt216 Pt216 D4T, 3TC NVP   D121H, D123N, I135V, S162C, K173S, D177E, T200A, Q207N, R211K, E224K  
Pt233 Pt233 D4T, 3TC NVP   K49R, V60I, D123E, K173R, D177E, T200E, I202V, Q207K, R211K Q174C 
Pt368 Pt368 D4T, 3TC NVP   D123S, D177N, T200E, I202V, Q207E, R211K