<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Charpentier (2008)
Title Drug resistance profiles for the HIV integrase gene in patients failing raltegravir salvage therapy.
Citation HIV Med
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 14
NumPts 3
Subtype B, CRF02_AG

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
Pt1 Pt1-BL None    E11D, A21T, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D256E, D278E  
  Pt1-W4 RAL Q148R  E11D, A21T, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D278E  
  Pt1-W8 RAL Q148R  E11D, A21T, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, V259I, D278E  
  Pt1-W11 RAL 11 G140GS, Q148QH, N155NH  E11D, A21T, A23AV, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D278E  
  Pt1-W22 RAL 22 G140GS, Q148QH  E11D, A21T, A23AV, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D256DE, D278E L101LF 
  Pt1-W39 RAL 39 G140GS, Q148QH  E11D, A21T, A23AV, D25E, S119G, T122I, T125A, V201I, I203M, T218S, L234I, D253E, D256DE, D278E L101LF 
Pt2 Pt2-BL None    E11D, V31I, I72IV, L101I, T112V, S119P, T124S, T125A, G134N, I135V, K136T, G163A, F181L, V201I, T206S, L234I, S255SN, D256E, R269K, D278N, S283G R228RK 
  Pt2-W12 RAL 12   E11D, V31I, L101I, T112V, S119P, T124S, T125A, G134N, I135V, K136T, G163A, F181L, G193GR, V201I, T206S, L234F, D256E, R269K, D278N, S283G G47GE 
  Pt2-W16 RAL 16 T66TA, E92EQ  E11D, V31I, L45LI, L101I, T112V, S119P, T124S, T125A, G134N, I135V, K136T, G163A, F181L, V201I, T206S, L234F, D256E, R269K, D278N, S283G  
  P2-W21 RAL 21 T66A, E92Q E138N E11D, V31I, L74I, L101I, T112V, S119P, T124S, T125A, G134N, I135V, K136T, G163A, F181L, S195G, V201I, T206S, L234F, D256E, R269K, D278N, S283G  
Pt3 Pt3-BL None    I72V, T124A, K156N, D167E, S283G, D288N  
  Pt3-W9 RAL   I72V, T124A, K156N, D167E, S283G, D288N  
  Pt3-W11 RAL 11 Q148QR  I72V, T124A, K156N, D167E, S283G, D288N  
  Pt3-W15 RAL 15 G140S, Q148R  I72V, T124TA, K156N, D167E, S283G, D288N