<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Goodman (2008)
Title Integrase inhibitor resistance involves complex interactions among primary and secondary resistance mutations: a novel mutation L68V/I associates with E92Q and increases resistance.
Citation IHDRW 2008
SelectedGene IN
SelectedSpecies HIV1
SelectedType Lab
NumIsolates 18
Lab Parent Strain HXB2

Lab IN Isolates (including Susceptibility Data)


IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
138K,147G+1 E138K, S147G, Q148R  PhenoSense EVG 154 
     PhenoSense RAL 34 
140S,148H G140S, Q148H  PhenoSense EVG >1,000 
     PhenoSense RAL >1,000 
148R,155H Q148R, N155H  PhenoSense EVG 229 
     PhenoSense RAL 102 
E138K E138K  PhenoSense EVG 0.6 
     PhenoSense RAL 0.9 
E92Q E92Q  PhenoSense EVG 40 
     PhenoSense RAL 6.0 
E92Q,N155H E92Q, N155H  PhenoSense EVG 125 
     PhenoSense RAL 105 
G140S G140S  PhenoSense EVG 4.0 
     PhenoSense RAL 1.6 
L68I  L68I PhenoSense EVG 0.9 
     PhenoSense RAL 0.9 
L68I,E92Q E92Q L68I PhenoSense EVG 43 
      PhenoSense RAL 7.6 
L68V  L68V PhenoSense EVG 1.6 
     PhenoSense RAL 1.0 
L68V,E92Q E92Q L68V PhenoSense EVG 67 
      PhenoSense RAL 14 
L68V,N155H N155H L68V PhenoSense EVG 51 
      PhenoSense RAL 24 
L68V,Q148R Q148R L68V PhenoSense EVG 139 
      PhenoSense RAL 53 
N155H N155H  PhenoSense EVG 36 
     PhenoSense RAL 21 
Q148H Q148H  PhenoSense EVG 5.3 
     PhenoSense RAL 18 
Q148K Q148K  PhenoSense EVG 50 
     PhenoSense RAL 27 
Q148R Q148R  PhenoSense EVG 109 
     PhenoSense RAL 35 
S147G S147G  PhenoSense EVG 9.4 
     PhenoSense RAL 1.0 

Database

Resources

Team