<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Van Baelen (2007)
Title Low level of baseline resistance to integrase inhibitors L731,988 and L810,810 in randomly selected subtype B and non-B HIV-1 strains.
Citation IHDRW 2007
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 47
NumPts 47
Subtype B, U, C, A, CRF02_AG, D, CRF01_AE, G

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
Pt1 1-1 None    V31I, S123G, K127R, K188R, V201I, I220L, I268V  
Pt10 10-2 None    V31I, M50I, S123G, K127R, V201I, K215N, Q216K, T218I, I220L  
Pt11 11-1 None    E11D, S24N, V31I, M50I, L101I, K111T, S123G, K127R, T206S, D232E, D278E  
Pt12 12-1 None    E10D, S123G, T124A, T125A, K127R, I135V, E157Q, K160Q, D256E  
Pt13 13-1 None    E10D, M50L, L74I, L101I, S123G, T124A, T125A, K127R, I135V, E157Q, K160Q, V176L, D256E  
Pt14 14-1 None    E10D, I72V, S123G, T124A, K127R, D232N  
Pt15 15-1 None    V31I, K42E, L101I, K111R, S119G, T122I, S123G, T125A, K127R, G193E, K211R, A265V, D278N  
Pt16 16-1 None    S17N, I72V, L101I, S123G, T124N, T125A, K127R, I135V, D167E, H171L, D232E, A265V  
Pt17 17-2 None    E10D, R20K, V31I, S39C, I113V, S123G, T124N, T125A, K127R, H171Q, Q216N, S230N, R231K  
Pt18 18-2 None    D6E, E10D, E13D, E96D, L101I, S119R, S123G, T124A, K127R, T206S, S230N, D279G S283G, R284G 
Pt19 19-1 None    E11D, K14R, S24N, L28I, V37I, S39C, L101I, S123G, T125A, K127R, K156N, K215N, N222K  
Pt2 2-1 None   A128T E11D, S17N, L28I, Q53K, I72V, L101I, K111R, T112R, T122I, S123G, T124A, K127R, K156N, V201I, T218S, D232E, D256E  
Pt20 20-1 None    E11D, S24T, S39C, M50I, I60M, I72V, L101I, S119P, T122I, S123G, T124A, K127R, V201I, N222H, K240R S283G, R284G 
Pt21 21-1 None    S17N, M50I, L101I, S119P, T122I, S123G, T124A, K127R, T206S, D256E  
Pt22 22-2 None    E11D, D25E, V31I, L101I, K111N, I113V, S119T, S123G, T125A, K127R  
Pt23 23-1 None    S17N, T112I, S119G, T122I, S123G, T124N, T125A, K127R, V201I  
Pt24 24-1 None   V151I V31I, K111N, T122I, S123G, T124N, K127R, V201I  
Pt25 25-4 None    D6E, E11D, V31I, K34R, I60M, I72V, L101I, I113V, S119G, T122I, S123G, T125A, K127R, G193E, K215N, D256E, D279G V281M 
Pt26 26-1 None    D6E, V31I, V37I, I72V, I113V, S123G, T125A, K127R, K136T, K156N D288N 
Pt27 27-1 None    V31I, I84M, E96D, L101I, T112V, S123G, T124N, K127R, V201I, L234I, D278A R284G 
Pt28 28-1 None    D6E, E10D, D25E, S39C, F100Y, L101I, T112V, S123G, T124A, T125A, K127R, K136Q, V201I, I203M, K211R, T218I, L234I, I268L, K273Q, D278A S283G 
Pt29 29-4 None    S17N, D25E, V31I, L45Q, F100Y, L101I, T112V, S123G, T124A, T125A, K127R, K136Q, E157Q, K160Q, V201I, T218I, Q221R, L234I, R269K, D278A S283G 
Pt3 3-4 None    D6T, K7E, E10D, E11D, V31I, V32I, L101I, S119P, T122I, S123G, T125A, K127R, S230N  
Pt30 30-1 None    K14R, D25E, K34R, L74I, F100Y, L101I, T112V, S123G, T124A, T125A, K127R, K136Q, V201I, T218I, L234I, D278A S283G, R284G 
Pt31 31-3 None    S17N, D25E, V31I, I84M, F100Y, L101I, T112V, S123G, T124A, T125A, K127R, K136Q, V201I, T218I, L234I, D278A S283G 
Pt32 32-1 None    K14R, D25E, V31I, I72V, L74I, E96D, F100Y, L101I, T112V, I113L, S123G, T124A, T125A, K127R, K136Q, V201I, K211R, L234V, D278A S283G 
Pt33 33-1 None    E11D, D25E, V31I, L45Q, F100Y, L101I, T112V, S123G, T124A, T125A, K127R, K136Q, S195T, V201I, T218I, L234I, R269K, D278A S283G 
Pt34 34-3 None    E11D, R20K, S24N, D25E, V31I, F100Y, L101I, T112V, S119P, T122I, S123G, T125A, K127R, K136Q, V201I, K211R, L234I, R269K, D278A S283G 
Pt35 35-2 None    S17N, D25E, V31I, F100Y, L101I, T112V, S123G, T124A, T125A, K127R, K136Q, V201I, T218I, L234I, A265V, R269K, D278A S283G 
Pt36 36-1 None    D25E, V31I, F100Y, L101I, T112V, S123G, T125A, K127R, K136Q, Y194H, V201I, T206S, L234I, R269K, D278A T218V, S283G 
Pt37 37-1 None    K14R, S24N, D25E, F100Y, L101I, G106A, T112V, S123G, T124A, T125A, K127R, K136Q, V201I, T218I, L234I, A265V S283G 
Pt38 38-3 None    E11D, V31I, G70E, L101I, T112I, S119R, S123G, T124A, T125A, K127R, G134D, K136T, V201I, T206S, Y227F, L234I, S255N, D256E S283G 
Pt39 39-2 None    K14R, R20K, V31I, L101I, T112V, S119T, S123G, T124A, T125A, K127R, G134N, I135V, K136T, V201I, T206S, Y227F, L234I, S255N, D256E S283G 
Pt4 4-1 None    E11D, E13D, S24N, L101I, S119P, T122I, S123G, K127R, K136N, T218S, D256E  
Pt40 40-3 None    K14R, V31I, I72V, L101I, T112V, S123G, T125A, K127R, G134S, K136Q, I141V, V165I, I208L, T218I, L234I, D279G  
Pt41 41-2 None    D6E, E11D, S17N, A21T, L101I, K111T, I113V, T122I, S123G, T125A, K127R, T206S  
Pt42 42-1 None    S17N, K34R, Y99F, L101I, T112V, I113V, S123G, T124A, T125A, K127R, V201I, L234I, D256E  
Pt43 43-1 None   T97A K7R, S17N, I72V, L101I, T112V, I113V, S123G, T124A, T125A, K127R, V201I, K219N, N222K, L234I S283G, D288N 
Pt44 44-1 None    K14R, A21T, V31I, S39N, I72V, L101I, T112V, S123G, T124A, T125A, K127R, G134N, I135V, K136Q, D167E, V201I, L234V S283G 
Pt45 45-1 None    K14R, V31I, T112V, I113V, S123G, T124A, T125A, K127R, K136Q, D167E, K173R, V201I, T218S, L234I S283G 
Pt46 46-1 None    K14R, R20K, V31I, L101I, T112V, S119T, S123G, T124A, T125A, K127R, G134N, I135V, K136T, V201I, T206S, Y227F, L234I, S255N, D256E I60T, S283G 
Pt47 47-1 None    K14R, V31I, I72V, Y99F, L101I, T112V, S123G, T124A, T125P, K127R, G134N, I135V, K136T, D167E, I191V, V201I, T206S, R269K S283G 
Pt5 5-1 None    D6E, K14R, V31I, A49T, Y99F, L101I, K111T, I113V, S119T, S123G, T124A, T125A, K127R, I135V, V201I, A205S, T206S, Q216K, S230N, D256E  
Pt6 6-1 None    E11D, S24D, L28I, V37I, S39C, I72V, L101I, T112A, S119P, S123G, K127R, V201I S283G 
Pt7 7-1 None    E11D, L28I, V37I, S39C, L101I, S123G, K127R, V201I, L234V R284G 
Pt8 8-1 None    E11D, A21T, G106A, I113V, S119P, S123G, T124N, K127R, A133T, D232E, D256E, K273R  
Pt9 9-1 None    K7R, S39C, L101I, S119P, T122I, S123G, K127R, K156N D286N 

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