<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Martinson (2007)
Title Selection and persistence of viral resistance in HIV-infected children after exposure to single-dose nevirapine.
Citation JAIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 64
NumPts 64
Subtype C


Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
CHB115B CHB115B None NVP   P4S, V35T, E36A, T39E, S48T, K122E, D123N, K166R, K173T, Q174R, D177E, I178V, T200A, Q207E, F214L, V245L, A272P, K275Q, T286A, E291D, V292I, I293V, P294Q, K323R, I329V, Q334R  
CHB115M CHB115M None NVP   P4S, V35PST, E36A, T39E, S48T, K122E, D123N, K166R, K173T, Q174R, D177E, T200A, Q207E, R211K, F214L, V245L, A272P, K275Q, T286A, E291D, V292I, I293V, P294Q, K323R, I329V, Q334R  
CHB142B CHB142B None NVP  Y181YC E6EG, V35T, E36A, T39E, K122E, D123G, S162F, K166R, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272S, T286A, E291D, V292I, I293V  
CHB142M CHB142M None NVP   V35T, E36A, T39E, W88WC, K122E, D123G, S162CFY, K173A, D177E, T200A, Q207E, R211K, V245Q, A272S, T286A, E291D, V292I, I293V  
CHB147B CHB147B None NVP  Y181C V35T, T39D, S48T, V60I, K173A, Q174K, D177E, T200A, Q207T, R211K, F214L, V245Q, A272P, T286A, E291D, V292I, I293V, D324E  
CHB147M CHB147M None NVP   V35T, T39D, S48T, V60I, K173A, Q174K, D177E, T200A, Q207A, R211K, F214L, V245Q, A272P, T286A, E291D, V292I, I293V  
CHB188B CHB188B None NVP   E6D, K20R, V35T, E36A, T39E, E40D, S48T, V60I, K122E, D123N, A158S, K166R, K173T, T200A, Q207E, V245L, A272P, K277T, T286A, E291D, V292I, I293V  
CHB188M CHB188M None NVP   E6D, K20KR, V35T, E36A, T39E, E40D, S48T, V60I, K122E, D123N, A158S, K166R, K173T, T200A, Q207E, V245L, D250E, S251D, A272P, K277T, T286A, E291D, V292I, I293V  
CHB200B CHB200B None NVP   V35T, E36A, T39D, A98S, K122E, D123N, S162A, K173T, Q174K, T200A, Q207E, R211K, A272P, T286A, E291D, V292I, I293V, P294Q  
CHB200M CHB200M None NVP   V35T, E36A, T39D, A98S, K122E, D123N, S162A, K173T, Q174K, T200A, Q207E, R211K, A272P, T286A, E291D, V292I, I293V, K331N R72RK 
CHB226B CHB226B None NVP   K20R, V35T, E36A, T39E, S48T, V60I, K122E, K173A, Q174E, D177E, I178V, T200A, Q207E, F214L, V245Q, A272P, K275Q, K281R, T286A, E291D, V292I, I293V  
CHB226M CHB226M None NVP   K20R, V35T, E36A, T39E, S48T, V60I, K122E, K173A, Q174K, D177E, I178V, T200A, Q207E, F214L, V245Q, A272P, K275Q, K281R, T286A, E291D, V292I, I293V, H315N  
CHB231B CHB231B None NVP   V35T, E36A, T39E, E40D, S48T, K122E, D123G, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, I329L  
CHB231M CHB231M None NVP   V35T, E36A, T39E, E40D, S48T, K122E, D123G, K173A, Q174K, D177E, T200A, Q207E, R211K, F214FL, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, I329IL, K331N  
CHB253B CHB253B None NVP   E6N, V35T, T39E, S48T, K104R, K122E, E138A, K173I, Q174K, I202V, Q207A, R211K, F214L, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, V314A N306K 
CHB253M CHB253M None NVP   E6KN, V35T, T39E, S48T, K104R, K122E, E138A, K173IMT, Q174K, T200TA, I202V, Q207A, R211KT, F214L, V245Q, E248DN, A272P, K277R, T286A, E291D, V292I, I293V  
CHB265B CHB265B None NVP   V21I, V35T, T39E, S48T, V60I, K122E, D123G, I135V, T165I, K173A, Q174K, D177E, T200A, Q207K, V245Q, T286A, V292I, I293V, I326V  
CHB265M CHB265M None NVP   V21I, V35T, T39E, S48T, V60I, K122E, D123G, I135V, T165I, K173A, Q174K, D177E, T200A, Q207K, V245Q, T286A, V292I, I293V, I326V L310PS 
CHB309B CHB309B None NVP   V35T, T39E, S48T, K122E, D123N, K173I, Q174K, T200A, Q207K, R211K, F214L, V245K, K277R, T286A, E291D, V292I, I293V, Q334L  
CHB309M CHB309M None NVP   T27TS, V35T, T39E, S48T, K122E, D123S, K173I, Q174K, T200A, Q207EK, R211K, F214L, V245VEKM, E248EDKN, K277R, T286A, E291D, V292I, I293V, Q334H G333N 
CHB374B CHB374B None NVP  Y181YC I2N, K22R, V35AT, E36A, T39E, S48T, K122E, D123G, S162C, K173A, Q174K, D177E, T200A, E203G, Q207E, V245Q, D250E, K277R, T286A, E291D, V292I, I293V, Q334E  
CHB374M CHB374M None NVP  K238T V35T, E36A, T39E, S48T, K122E, D123G, S162C, K173A, Q174K, D177E, T200A, E203G, Q207E, R211K, V245Q, D250E, K277R, T286A, E291D, V292I, I293V, I326V, Q334E  
CHB398B CHB398B None NVP  Y181C V35T, E36A, T39E, S48E, V60I, K122E, D123S, I135R, S162A, K173A, D177E, Q207A, R211K, V245Q, D250E, A272P, E291D, V292I, I293V, Q334L K13R 
CHB398M CHB398M None NVP   V35RT, E36A, T39E, S48E, V60I, K122E, D123S, I135S, S162A, K173A, D177E, Q207A, R211K, V245Q, D250E, A272P, E291D, V292I, I293V, Q334L S134K, N136D, N137T 
CHB4B CHB4B None NVP   V35T, E36A, T39E, E40D, S48T, S68G, K122E, K173A, D177E, I178M, T200E, E204K, Q207D, V245Q, K277R, T286A, E291D, V292I, I293V T84TA, T128A 
CHB4M CHB4M None NVP   V35T, E36A, T39E, E40D, S48T, K122E, D123G, K173A, D177E, I178M, T200E, E204K, Q207D, V245Q, K277R, T286A, E291D, V292I, I293V  
CHB5B CHB5B None NVP   V35T, T39E, S48T, K122E, D123S, K173T, T200A, Q207E, D250E, S251D, A272P, K277R, L283I, T286A, E291D, V292I, I293V, E308A  
CHB5M CHB5M None NVP   V35T, T39E, S48T, K122E, D123S, K173T, T200A, Q207E, D250E, S251D, A272P, K277R, L283I, T286A, E291D, V292I, I293V, E308A  
CHB64B CHB64B None NVP  Y181YC V35A, E36ED, T39E, S48T, K122E, D123S, K173A, D177E, T200A, E204Q, Q207A, R211K, V245Q, A272P, T286A, V292I, I293V, P294Q, E297A, G333S, Q334H  
CHB64M CHB64M None NVP   V35T, T39E, S48T, K122E, D123GS, K173A, D177E, T200A, Q207A, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, P294Q, E297EA, G333S, Q334H  
CHB83B CHB83B None NVP   V35T, T39E, S48T, V60I, A98S, K122E, D123N, I135V, I142V, K173T, Q174K, I178L, T200A, R211K, V245Q, S251SC, A272P, K281R, E291D, V292I, I293V, P294T, E297G, I326V  
CHB83M CHB83M None NVP   V35T, T39E, S48T, V60VI, A98S, K122E, D123DN, I135V, I142IV, K173T, Q174K, I178IL, T200A, R211K, V245Q, A272P, K281R, E291D, V292I, I293V, P294PT, E297EK, I326IV  
KEH109B KEH109B None NVP  K103KN, V106VA V35T, E36A, T39E, S48T, V60I, K122E, D123S, I135V, I142V, S162A, K166R, K173A, Q174K, D177E, G196E, T200A, Q207D, R211K, V245Q, S251N, K277R, T286A, E291D, V292I, I293V, K311R  
KEH109M KEH109M None NVP   V35T, E36A, T39E, S48T, V60I, K122E, D123GS, I135V, I142V, S162A, K166R, K173A, Q174K, D177E, G196E, T200A, Q207D, R211K, V245Q, S251N, K277R, T286A, E291D, V292I, I293V, K311R  
KEH142B KEH142B None NVP   K20R, V35T, T39E, K122E, D123G, K173A, Q174K, T200Q, Q207E, R211K, V245N, D250N, K277R, T286A, E291D, V292I, I293V, E308EA, L310I  
KEH142M KEH142M None NVP   V35T, T39EK, K122E, D123G, E138ED, I142M, S162R, M164L, T165A, E169D, K173A, Q174K, I180IL, T200A, Q207E, R211K, V245N, A272AP, V276VA, K277R, Q278HN, T286A, E291D, V292I, I293V, L310I T139P, Y146YC, N147NH, S163W 
KEH158B KEH158B None NVP   T27S, V35T, E36A, T39E, S48E, V60I, D121H, K122E, D123S, K173T, D177E, T200A, Q207E, R211K, V245K, A272P, K277R, T286A, E291D, V292I, I293V  
KEH158M KEH158M None NVP   T27S, V35T, E36A, T39E, S48AE, V60I, D121H, K122E, D123S, K173T, D177E, T200A, Q207E, R211K, V245K, A272P, K277R, T286A, E291D, V292I, I293V  
KEH15B KEH15B None NVP   V35T, E36A, T39E, S48T, E53D, K166R, K173E, Q174R, D177E, T200A, Q207K, R211K, V245Q, K277R, T286A, E291D, V292I, I293V  
KEH15M KEH15M None NVP   V35T, E36A, T39E, S48T, E53ED, K166R, K173E, Q174R, D177E, T200A, Q207K, R211K, V245Q, K277R, T286A, E291D, V292I, I293V, Q334DE R172RG 
KEH161B KEH161B None NVP  V106A V35T, T39E, S48T, K122E, D123G, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, K259R, A272P, K277R, T286A, E291D, V292I, I293V, Q334D  
KEH161M KEH161M None NVP   E28A, V35T, T39E, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V  
KEH165B KEH165B None NVP  K103KN, Y188YC V8G, D17G, T27P, V35KT, E36A, T39E, S48T, V60VI, K122E, D123G, K166KR, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V E28P, K30E 
KEH165M KEH165M None NVP   M16L, K20R, V35A, E36A, T39E, S48T, K122E, D123G, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, K331N N57K 
KEH169B KEH169B None NVP  K103N P4S, V35T, E36A, T39E, E40D, S48T, V60I, K101KR, K122E, D123S, A158AS, S163ST, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, K311R  
KEH169M KEH169M None NVP   P4S, V35T, E36A, T39E, E40D, S48T, V60I, K122E, D123S, E138A, T165I, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E308K, K311R  
KEH181B KEH181B None NVP  Y181C V35T, E36A, T39E, S48T, V60I, K122E, D123G, I135V, I142L, K173A, Q174E, D177E, T200A, Q207E, V245Q, A272P, T286A, E291D, V292I, I293V, L303M, E312D  
KEH181M KEH181M None NVP  K103KN, Y181YC, G190GA V35T, E36A, T39E, S48T, V60I, K122E, D123G, I135V, I142L, K166KR, K173A, Q174E, D177E, T200A, Q207E, V245Q, A272P, K277KR, T286A, E291D, V292I, I293V, L303LM, E312D, Q334QH  
KEH205B KEH205B None NVP  K103N, Y188YC E6Q, V8VI, K11KQ, K32R, V35T, E36A, T39E, S48T, V60I, K122E, D123GS, S162T, K173A, D177E, T200A, Q207G, R211K, A272P, R284G, T286A, E291D, V292I, I293V, K311E, E312D, V317G G316C 
KEH205M KEH205M None NVP   E6X, K11HQ, K32KR, V35T, E36A, T39E, S48T, V60I, K101KQ, K122E, D123G, T165TI, K173A, D177E, T200A, Q207G, R211K, V245E, A272P, K277KR, T286A, E291D, V292I, I293V  
KEH210B KEH210B None NVP   K20R, V35T, E36A, T39E, S48T, V60I, I135T, K173A, Q174K, D177E, T200A, Q207K, R211Q, F214L, V245Q, A272P, I274V, K277R, T286A, E291D, V292I, I293V, V317A Q222Q* 
KEH210M KEH210M None NVP  G190GA K20R, V35T, E36A, T39E, S48T, V60I, I135T, K173A, Q174K, D177E, T200A, Q207K, R211Q, F214L, V245Q, A272PS, K275KR, K277R, T286A, E291D, V292I, I293V, V317A  
KEH2B KEH2B None NVP  Y181C, Y188YC K20R, V35T, T39E, S48T, V60I, K122E, I135IV, S162Y, K173T, T200A, Q207E, R211K, K223R, V245Q, A272P, I274V, Q278N, T286A, E291D, V292I, I293V, D324E  
KEH2M KEH2M None NVP   K20R, V35T, E36EA, T39E, S48T, V60I, K122E, D123DG, S162Y, K173AT, D177DE, T200A, Q207E, R211RK, K223R, V245Q, A272P, I274V, Q278NY, T286A, E291D, V292I, I293V, D324E  
KEH32B KEH32B None NVP   V8I, V35T, T39E, S48T, V60I, K122E, D123G, I135V, K173A, Q174K, D177E, T200A, Q207A, R211K, F214L, V245L, A272P, K277T, E291D, V292I, I293V  
KEH32M KEH32M None NVP   V8I, V35T, T39E, S48T, V60I, K122E, D123G, I135V, K173A, Q174K, D177E, T200A, Q207A, R211K, F214L, V245L, A272P, K277T, E291D, V292I, I293V  
KEH44B KEH44B None NVP  Y181C K32E, V35T, E36A, T39K, S48T, D123E, I135R, S162C, K173A, D177E, I178L, T200A, Q207E, R211K, V245E, A272P, T286A, E291D, V292I  
KEH44M KEH44M None NVP   K32E, V35T, E36A, T39E, S48T, D121DH, K122KE, D123E, I135R, S162C, K173A, D177E, I178L, T200A, Q207E, R211K, V245E, A272P, T286A, E291D, V292I  
KEH56B KEH56B None NVP   V35T, E36A, T39E, S48T, K122E, D123S, A158S, K173A, T200A, V245Q, E291D, V292I, I293V, V317A  
KEH56M KEH56M None NVP   V35T, E36A, T39E, S48T, K122E, D123S, A158S, K173A, T200A, V245Q, E291D, V292I, I293V, V317A  
KEH62B KEH62B None NVP   V35T, E36A, T39E, S48T, V60I, K122E, D123N, K173A, Q174K, D177E, I178M, T200A, Q207K, R211E, F214L, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, R307K, V317A, S322T  
KEH62M KEH62M None NVP   V21G, V35T, E36A, T39E, S48T, V60I, K122E, D123N, K173A, Q174K, D177E, I178M, T200A, Q207K, R211E, F214L, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, R307K, V317A, S322T  
KEH79B KEH79B None NVP  K103N V35T, E36A, T39E, E40D, S48T, V60I, K122E, D123N, T165I, K173A, Q174K, T200A, Q207D, V245Q, A272P, K275R, T286A, E291D, V292I, I293V  
KEH79M KEH79M None NVP   V35T, E36A, T39E, E40ED, S48T, V60I, K122E, D123N, T165I, K173A, Q174K, T200A, Q207D, V245Q, A272P, K275R, T286A, E291D, V292I, I293V