<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Eshleman (2006)
Title Phenotypic drug resistance patterns in subtype A HIV-1 clones with nonnucleoside reverse transcriptase resistance mutations.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 35
NumPts 10
Subtype A, D


Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
164 164-c5 None NVP  K103N K20R, V21I, V35T, T39R, K43E, V60I, K122E, D123N, K173S, Q174K, D177E, Q207A, R211N, V245Q, A272P, E291D, I293V, P294T, E312D, D324E I326R 
  164-c32 None NVP  Y181C V21I, V35T, T39S, K49Q, E138G, K173S, Q174K, D177E, V179I, Q207A, R211N, V245Q, A272P, E291D, I293V, P294T, E312D, D324E I326R 
  164-c36 None NVP  Y181C K20R, V21I, V35T, T39K, K43E, I50V, K122E, D123N, T139I, I142L, K173S, Q174K, D177E, Q207A, R211N, V245Q, A272P, E291D, I293V, P294T, E312D L92S, I326R, E328V 
  164-c51 None NVP  K103N K20R, V21I, V35T, T39G, V60I, K122E, D123N, K173S, Q174K, D177E, V179I, Q207A, R211N, V245Q, A272P, E291D, I293V, P294T, E312D, D324E I326R 
  164-c56 None NVP  G190A K20R, V21I, V35T, T39K, K43E, I50V, K122E, D123N, E138G, I142L, K173S, Q174K, D177E, V179I, Q207A, R211N, V245Q, A272P, E291D, I293V, P294T, E312D, D324E I326R 
185 185-c4a None NVP  Y181C K11T, K20R, V21I, V35T, T39K, V60I, K122E, D123N, I135T, K173T, D177G, T200K, I202V, Q207A, R211S, V245Q, E248D, K281R, E291D, V292I, I293V, P294T, V314M, I326V, I329V  
  185-c5 None NVP   K11T, K20R, V21I, V35T, T39K, V60I, T69A, K122E, D123N, I135T, K173T, D177G, T200K, I202V, Q207A, R211N, V245Q, E248D, K281R, R284K, T286A, E291D, V292I, I293V, P294T, V314M, I326V, I329V  
  185-c12 None NVP  G190A K11T, K20R, V21I, V35T, T39K, V60I, K122E, D123N, I135T, K173T, D177G, T200N, I202V, Q207A, R211N, V245Q, E248D, K281R, T286A, E291D, V292I, I293V, P294T, V314M, I326V, I329V  
545 545-c64 None NVP  Y181C K11T, K20R, V21I, V35T, T39R, D123N, T165I, K173S, D177E, V179I, G196E, I202V, Q207A, R211K, V245Q, E248D, S251I, K277R, T286A, E291D, P294T  
667 667-c8A None NVP  Y181S K11T, K20R, V21I, V35T, T39K, K43E, D123N, K173T, Q174K, D177E, V179I, I202V, Q207A, R211S, V245Q, E248D, T286A, E291D, V292I, I293V, E312D  
  667-c9 None NVP  Y181C K11T, K20R, V21I, V35T, T39K, K43E, D123N, K173T, Q174K, D177E, V179I, I202V, Q207A, R211S, V245Q, E248D, T286A, E291D, V292I, I293V, E312D  
  667-c16A None NVP   K11T, K20R, V21I, V35T, T39K, K43E, D123N, K173T, Q174K, D177E, V179I, I202V, Q207A, R211S, V245Q, E248D, K281R, T286A, E291D, V292I, I293V, E312D  
  667-c27 None NVP  K103N K11T, K20R, V21I, V35T, T39K, K43E, D123N, E169K, K173T, Q174K, D177E, V179I, I202V, Q207A, R211S, V245Q, E248D, K281R, T286A, E291D, V292I, I293V, E312D A299AP 
  667-c41 None NVP  G190A K11T, K20R, V21I, V35T, T39K, K43E, D123N, K173T, Q174K, D177E, V179I, I202V, Q207A, R211S, V245Q, E248D, T286A, E291D, V292I, I293V, P294Q, E312D  
703 703-c8 None NVP  K103N V35T, T39L, K122E, D123G, A158S, K173S, Q174K, D177E, I178V, V179I, T200A, I202V, Q207A, V245M, K277R, L282C, R284K, T286V, I293V  
842 842-c15 None NVP  G190A K11T, K20R, V21I, V35T, T39K, V60I, K122E, D123N, K173S, D177G, V179I, T200A, I202V, Q207A, V245Q, E248D, T286A, E291D, I293V, P294T, E312D  
  842-c30 None NVP  Y181C K11T, K20R, V21I, V35T, T39K, V60I, K122E, D123N, K173A, D177G, V179I, T200A, I202V, Q207A, R211K, V245Q, E248D, T286A, E291D, V292I, I293V, P294T, E312D  
  842-c31 None NVP  K103N K11T, K20R, V21I, V35T, T39K, V60I, K122E, D123N, K173A, D177G, V179I, G196E, T200A, I202V, Q207A, V245Q, E248D, T286A, E291D, I293V, P294T, K311R, E312D  
847 847-c12 None NVP  Y181C V35T, V60I, D121H, K122E, I135T, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, V245K, D250E, T286A, E291D, V292I, I293V, E312D, I326V  
  847-c15 None NVP   K20R, V35T, V60I, D121H, K122E, I135T, K173L, Q174K, D177E, T200A, Q207A, R211S, V245K, D250E, T286A, E291D, V292I, I293V, E312D, A327V  
  847-c17 None NVP  K103N V35T, V60I, D121H, K122E, I135T, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, V245K, D250E, T286A, E291D, V292I, I293V, E312D, K323R  
SE599 599-pre None None   V35T, E40D, I50V, K122E, D123S, I135T, I142T, K173S, D177E, V179I, Q207A, R211S, F214L, V245Q, A272P, E291D, I293V, P294T, L310I, E312D, D324E  
  599-c1 None NVP  Y181C V35T, E40D, I50V, K122E, D123S, I135T, I142T, K173S, D177E, V179I, Q207A, R211S, F214L, V245Q, A272P, E291D, I293V, P294T, L310I, E312D, D324E  
  599-c13 None NVP   I31T, V35T, E40D, I50V, K122E, D123S, I135T, I142T, K173S, D177E, V179I, Q207A, R211S, F214L, V245Q, A272P, E291D, I293V, P294T, L310I, E312D, D324E  
  599-post None NVP  Y181YC V35T, E40D, I50V, K122E, D123S, I135T, I142T, K173S, D177E, V179I, Q207A, R211S, F214L, V245Q, A272P, E291D, I293V, P294T, L310I, E312D, D324E  
SE687 687-pre None None   E6D, V35T, V60I, K122E, D123S, I135T, K166R, K173ILM, Q174K, D177E, I178IMV, V179I, G196E, Q207A, R211S, V245M, D250E, K277R, T286A, E291D, V292VI, I293V, P294T, E312D  
  687-c2 None NVP V75M K103N E6D, V35T, V60I, K122E, D123S, I135T, K166R, K173I, Q174K, D177E, I178M, V179I, G196E, Q207A, R211S, V245M, D250E, K277R, T286A, E291D, V292I, I293V, P294T, E312D N265D 
  687-c3 None NVP V75M K103N E6D, V35T, V60I, K122E, D123S, I135T, K166R, K173I, Q174K, D177E, I178M, V179I, G196E, Q207A, R211S, V245M, D250E, K277R, T286A, E291D, V292I, I293V, P294T, E312D P59S 
  687-c4 None NVP   E6D, V35T, V60I, K122E, D123S, I135T, K166R, K173L, Q174K, D177E, I178M, V179I, E194D, G196E, Q207A, R211S, V245M, D250E, K277R, T286A, E291D, I293V, P294T, E312D  
  687-post None NVP V75VM K103KN, Y181YC E6D, V35T, V60I, K122E, D123S, I135T, K166R, K173IM, Q174K, D177E, I178IMV, V179I, G196E, Q207A, R211S, V245M, D250E, K277R, T286A, E291D, V292VI, I293V, P294T, E312D  
SE790 790-pre None None   V35IT, K49R, V60I, D121Y, K122E, D123DE, I135T, D177DE, T200I, Q207E, R211K, V245K, D250E, A272P, K277R, L282C, L283I, T286A, I293V, P294T, E298D  
  790-c3 None NVP   K11T, K20R, V21I, V35T, K122E, D123S, K173S, Q174K, D177E, V179I, T200A, I202V, Q207T, R211S, V245Q, V261I, T286A, E291D, V292I, I293V, P294T, E312D, I329V E248C, D256G 
  790-c7 None NVP  Y181C K11T, K20R, V21I, V35T, K122E, D123N, K173S, D177G, V179I, T200A, I202V, Q207A, R211S, V245Q, V261I, T286A, E291D, V292I, I293V, P294T, E312D, I329V E248C 
  790-c11 None NVP  G190A K11T, K20R, V21I, V35T, K122E, D123S, K173S, Q174K, D177G, V179I, T200A, I202V, Q207A, R211S, V245Q, V261I, T286A, E291D, V292I, I293V, P294T, E312D, I329V N136S, E248C 
  790-post None NVP  Y181YC K11T, K20R, V21I, V35T, K122E, D123S, K173S, D177G, V179I, T200A, I202V, Q207A, R211S, V245Q, V261I, T286A, E291D, V292I, I293V, P294T, E312D E248C