<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Takehisa (2007)
Title Generation of infectious molecular clones of simian immunodeficiency virus from fecal consensus sequences of wild chimpanzees.
Citation J Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup CPZ
NumIsolates 5
NumPts 3
Host Chimpanzee


Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
TAN1 SIVcpzTAN1 None None M41L, T215E V179D T7V, K11Q, P14E, T27S, E28K, K32E, V35T, T39K, I50V, V60I, S68T, T69S, K101R, K103R, K104N, V118I, K122P, I135L, I142K, Y144F, E169D, Q174E, N175H, I178V, V189I, E194N, G196E, Q197E, T200K, E203K, E204K, R211T, F214L, H221Y, K223E, E224K, L228M, D237N, V245T, D250E, S251Q, A272H, V276T, Q278E, L283I, T286V, A288G, I293V, P294E, L295M, E297R, A304E, R307K, E308Q, P313K, H315Q, V317A, S322K, D324P, P345E, F346G, R356K, M357S, A360T, D364E, V365I, K366R, T369A, E370G, A371L, V372I, A376G, T377N, V381I, T386V, I393V, Q394S, E404D, A408V, I411V, V417I, V423I, K424R, K431S, E432D, V435P, G436E, E449D, T450S, L452K, K454R, D460N, K465R, V466S, T470E, D471N, K476Q, T477A, I482V, H483D, Q487K, L491A, E492Q, A502V, L503M, I505V, I506L, A508G, Q509L, K512Q, E514D, L517I, Q524K, K527Q, E529T, V531I, Q547E, A554K, V559I P9K, E40T, K49A, V90L, S105M, E138N, I195E, K201L, P243N, K249P, D256H, V292P, K323L, I326Q, E328A, R358P, K385I, K390L, E399S, A400Q, Q428N, E430L, Q464Y, V467K, S468D, Q480W, E516P, S519E, E523Q, I526T, K530A, G555N 
TAN2 SIVcpzTAN2 None None M41L, T215E V179D I5V, T7V, K11Q, P14E, T27S, E28K, K32E, V35T, T39N, V60I, T69S, A98S, K101R, K103R, K104N, V118I, K122P, I135L, I142K, Y144F, E169D, Q174E, N175H, I178V, V189I, G196E, Q197E, T200K, E203K, E204K, R211V, F214L, H221Y, K223E, E224K, L228M, V245T, D250E, S251Q, A272H, V276T, Q278E, L283I, T286V, A288G, E291D, I293V, P294E, E297R, A304E, R307K, E308Q, H315Q, V317A, S322K, D324P, I329V, P345E, F346G, R356K, M357L, A360T, D364E, V365I, K366R, T369A, E370G, A371L, V372I, A376G, T377N, T386V, I393V, Q394S, E404D, A408V, I411V, V417I, V423I, K424R, K431T, E432D, V435P, G436E, T450S, L452K, K454R, K465R, V466T, T470E, D471N, K476Q, T477A, H483D, Q487R, L491A, E492Q, A502V, L503I, I505V, I506L, A508G, Q509L, K512Q, E514D, L517I, K527Q, E529T, V531I, Q547E, A554K, V559I P9K, E40T, K49A, V90L, S105M, E138N, E194S, I195E, K201L, D237H, P243N, K249P, D256H, K287KE, V292P, P313N, K323L, I326Q, E328A, R358P, K385I, K390L, E399S, A400Q, Q428N, E430L, Q464Y, V467K, S468D, Q480W, E516P, S519E, E523Q, I526T, K530A, G555N 
  Consensus None None M41L, T215E V179D I5V, T7V, K11Q, P14E, T27S, E28K, K32E, V35T, T39N, V60I, T69S, A98S, K101R, K103R, K104N, V118I, K122P, I135L, I142K, Y144F, E169D, Q174E, N175H, I178V, V189I, G196E, Q197E, T200K, E203K, E204K, R211V, F214L, H221Y, K223E, E224K, L228M, V245T, D250E, S251Q, A272H, V276T, Q278E, L283I, T286V, A288G, E291D, I293V, P294E, E297R, A304E, R307K, E308Q, H315Q, V317A, S322K, D324P, I329V, P345E, F346G, R356K, M357L, A360T, D364E, V365I, K366R, T369A, E370G, A371L, V372I, A376G, T377N, T386V, I393V, Q394S, E404D, A408V, I411V, V417I, V423I, K424R, K431T, E432D, V435P, G436E, T450S, L452K, K454R, K465R, V466T, T470E, D471N, K476Q, T477A, H483D, Q487R, L491A, E492Q, A502V, L503I, I505V, I506L, A508G, Q509L, K512Q, E514D, L517I, K527Q, E529T, V531I, Q547E, A554K, V559I P9K, E40T, K49A, V90L, S105M, E138N, E194S, I195E, K201L, D237H, P243N, K249P, D256H, V292P, P313N, K323L, I326Q, E328A, R358P, K385I, K390L, E399S, A400Q, Q428N, E430L, Q464Y, V467K, S468D, Q480W, E516P, S519E, E523Q, I526T, K530A, G555N 
  clone: TAN2.69 None None M41L, T215E V179D I5V, T7V, K11Q, P14E, T27S, E28K, K32E, V35T, T39N, V60I, T69S, A98S, K101R, K103R, K104N, V118I, K122P, I135L, I142K, Y144F, E169D, Q174E, N175H, I178V, V189I, G196E, Q197E, T200K, E203K, E204K, R211V, F214L, H221Y, K223E, E224K, L228M, V245T, D250E, S251Q, A272H, V276T, Q278E, L283I, T286V, A288G, E291D, I293V, P294E, E297R, A304E, R307K, E308Q, H315Q, V317A, S322K, D324P, I329V, P345E, F346G, R356K, M357L, A360T, D364E, V365I, K366R, T369A, E370G, A371L, V372I, A376G, T377N, T386V, I393V, Q394S, E404D, A408V, I411V, V417I, V423I, K424R, K431T, E432D, V435P, G436E, T450S, L452K, K454R, K465R, V466T, T470E, D471N, K476Q, T477A, H483D, Q487R, L491A, E492Q, A502V, L503I, I505V, I506L, A508G, Q509L, K512Q, E514D, L517I, K527Q, E529T, V531I, Q547E, A554K, V559I P9K, E40T, K49A, V90L, S105M, E138N, E194S, I195E, K201L, D237H, P243N, K249P, D256H, V292P, P313N, K323L, I326Q, E328A, R358P, K385I, K390L, E399S, A400Q, Q428N, E430L, Q464Y, V467K, S468D, Q480W, E516P, S519E, E523Q, I526T, K530A, G555N 
TAN3 SIVcpzTAN3 None None M41L, T215E V179D I5V, T7V, K11Q, P14E, T27S, E28R, K32E, V35T, T39N, V60I, K64R, S68T, T69S, A98S, K101R, K103R, K104N, V118I, K122P, I135L, I142K, Y144F, E169D, Q174E, N175H, I178V, V189I, G196E, Q197E, T200K, E203K, E204K, F214L, H221Y, K223E, E224K, L228M, D237N, V245T, D250E, S251Q, A272H, V276T, Q278E, L283I, T286V, A288G, E291D, I293V, P294E, L295M, E297R, A304E, R307K, E308Q, H315Q, V317A, S322K, D324P, I329V, P345E, F346G, R356K, M357L, A360T, D364E, V365I, K366R, T369A, E370G, A371L, V372I, A376G, T377N, V381I, T386V, I393V, Q394S, E404D, A408V, I411V, V417I, V423I, K424R, K431T, E432D, V435P, G436E, T450S, L452K, K454R, V466T, T470E, D471N, K476Q, T477A, H483D, Q487KR, L491A, E492Q, A502V, L503M, I505V, I506L, A508G, Q509L, K512Q, E514D, L517I, K527Q, E529A, V531I, Q547E, A554K, K558R P9K, E40T, K49A, V90L, S105M, E138N, E194S, I195E, K201L, R211L, P243N, K249P, D256H, V292P, P313DE, K323L, I326Q, E328A, R358P, K385I, K390L, E399S, A400Q, Q428N, E430L, Q464Y, V467R, S468D, Q480W, E516P, S519E, E523Q, I526T, K530A, G555N 
  Consensus None None M41L, T215E V179D I5V, T7V, K11Q, P14E, T27S, E28R, K32E, V35T, T39N, V60I, K64R, S68T, T69S, A98S, K101R, K103R, K104N, V118I, K122P, I135L, I142K, Y144F, E169D, Q174E, N175H, I178V, V189I, G196E, Q197E, T200K, E203K, E204K, F214L, H221Y, K223E, E224K, L228M, D237N, V245T, D250E, S251Q, A272H, V276T, Q278E, L283I, T286V, A288G, E291D, I293V, P294E, L295M, E297R, A304E, R307K, E308Q, P313E, H315Q, V317A, S322K, D324P, I329V, P345E, F346G, R356K, M357L, A360T, D364E, V365I, K366R, T369A, E370G, A371L, V372I, A376G, T377N, V381I, T386V, I393V, Q394S, E404D, A408V, I411V, V417I, V423I, K424R, K431T, E432D, V435P, G436E, T450S, L452K, K454R, V466T, T470E, D471N, K476Q, T477A, H483D, Q487R, L491A, E492Q, A502V, L503M, I505V, I506L, A508G, Q509L, K512Q, E514D, L517I, K527Q, E529A, V531I, Q547E, A554K, K558R P9K, E40T, K49A, V90L, S105M, E138N, E194S, I195E, K201L, R211L, P243N, K249P, D256H, V292P, K323L, I326Q, E328A, R358P, K385I, K390L, E399S, A400Q, Q428N, E430L, Q464Y, V467R, S468D, Q480W, E516P, S519E, E523Q, I526T, K530A, G555N 
  clone: TAN3.1 None None M41L, T215E V179D I5V, T7V, K11Q, P14E, T27S, E28R, K32E, V35T, T39N, V60I, K64R, S68T, T69S, A98S, K101R, K103R, K104N, V118I, K122P, I135L, I142K, Y144F, E169D, Q174E, N175H, I178V, V189I, G196E, Q197E, T200K, E203K, E204K, F214L, H221Y, K223E, E224K, L228M, D237N, V245T, D250E, S251Q, A272H, V276T, Q278E, L283I, T286V, A288G, E291D, I293V, P294E, L295M, E297R, A304E, R307K, E308Q, P313E, H315Q, V317A, S322K, D324P, I329V, P345E, F346G, R356K, M357L, A360T, D364E, V365I, K366R, T369A, E370G, A371L, V372I, A376G, T377N, V381I, T386V, I393V, Q394S, E404D, A408V, I411V, V417I, V423I, K424R, K431T, E432D, V435P, G436E, T450S, L452K, K454R, V466T, T470E, D471N, K476Q, T477A, H483D, Q487R, L491A, E492Q, A502V, L503M, I505V, I506L, A508G, Q509L, K512Q, E514D, L517I, K527Q, E529A, V531I, Q547E, A554K, K558R P9K, E40T, K49A, V90L, S105M, E138N, E194S, I195E, K201L, R211L, P243N, K249P, D256H, V292P, K323L, I326Q, E328A, R358P, K385I, K390L, E399S, A400Q, Q428N, E430L, Q464Y, V467R, S468D, Q480W, E516P, S519E, E523Q, I526T, K530A, G555N