<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author McColl (2007)
Title Resistance and cross-resistance to first generation integrase inhibitors: insights from a phase 2 study of elvitegravir (GS-9137).
Citation IHDRW 2007
SelectedGene IN
SelectedSpecies HIV1
SelectedType Lab
NumIsolates 14
Lab Parent Strain NL43

Lab IN Isolates (including Susceptibility Data)


IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
138K E138K V151I PhenoSense EVG 0.7 
      PhenoSense RAL 0.9 
138K-147G+1 E138K, S147G, Q148R V151I PhenoSense EVG 175 
      PhenoSense RAL 34 
140S G140S V151I PhenoSense EVG 5.0 
      PhenoSense RAL 2.0 
140S-148H G140S, Q148H V151I PhenoSense EVG >1,000 
      PhenoSense RAL >1,000 
147G S147G V151I PhenoSense EVG 8.0 
      PhenoSense RAL 1.0 
148H Q148H V151I PhenoSense EVG 6.4 
      PhenoSense RAL 20 
148K Q148K V151I PhenoSense EVG 67 
      PhenoSense RAL 34 
148R Q148R V151I PhenoSense EVG 118 
      PhenoSense RAL 30 
155H N155H V151I PhenoSense EVG 38 
      PhenoSense RAL 23 
66I T66I V151I PhenoSense EVG 15 
      PhenoSense RAL 1.4 
66I-147G T66I, S147G V151I PhenoSense EVG 46 
      PhenoSense RAL 2.5 
66I-92Q T66I, E92Q V151I PhenoSense EVG 145 
      PhenoSense RAL 33 
92Q-155H E92Q, N155H V151I PhenoSense EVG 166 
      PhenoSense RAL 135 
IE92Q E92Q V151I PhenoSense EVG 33 
      PhenoSense RAL 6.0 

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