<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Novitsky (2007)
Title The reverse transcriptase 67N 70R 215Y genotype is the predominant TAM pathway associated with virologic failure among HIV type 1C-infected adults treated with ZDV/ddI-containing HAART in southern Africa.
Citation ARHR
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 61
NumPts 23
Subtype C, CRF11_cpx


Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
0898 0898_0019 None    T12S, I15V, L19I, N37S, R41K, I62V, L63AS, H69K, A71T, V77I, I93L G94E 
  0898_7976 None    T12S, I15V, L19I, N37S, R41K, I62V, L63A, H69K, A71T, V77I, I93L  
  0898_6451 None    T12S, I15V, N37S, R41K, I62V, L63A, H69K, A71T, I72IV, V77I, I93L  
1025 1025_0078 None    T12S, I15V, L19V, M36L, N37S, R41K, H69K, L89I, I93L  
  1025_0773 None    T12S, I15V, L19V, M36L, N37S, R41K, L63P, I64IM, H69K, L89I, I93L  
1072 1072_0105 None    T12S, I15V, L19I, E35ED, M36I, R41K, H69K, L89M, I93L  
  1072_1862 None    T12S, I15V, L19I, M36I, R41K, H69K, L89LM, I93L  
  1072_2326 None    T12S, I15V, L19I, M36I, R41K, H69K, L89LM, I93L  
  1072_2794 None    T12S, I15V, L19I, M36I, R41K, H69K, I93L  
  1072_8477 None    T12S, I15V, L19I, M36I, R41K, H69K, I93L  
1144 1144_0155 None    T12S, I15V, L19I, M36I, R41K, Q61E, L63P, H69K, I93L  
  1144_0720 None    Q7QR, T12S, I15V, L19I, M36I, R41K, Q61E, L63P, I66IV, H69K, L89M, I93L  
  1144_0794 None    T12S, I15V, L19I, M36I, R41K, Q61E, L63P, H69K, L89M, I93L  
1194 1194_0201 None    T12S, I15IV, L19IV, E35D, M36I, R41K, L63P, H69K, L89M, I93L  
  1194_0548 None    T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, L89M, I93L  
  1194_2114 None    T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, L89M, I93L  
  1194_2315 None    T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, L89M, I93L  
  1194_2627 None    T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, L89M, I93L  
  1194_2855 None    T12S, I15V, L19IV, E35D, M36I, R41K, L63P, H69K, L89M, I93L  
1195 1195_0208 None    T12S, I15V, L19I, N37NS, R41K, L63P, H69K, V77I, L89M, I93L  
  1195_1995 None    T12S, I15V, L19I, N37S, R41K, L63P, H69K, V77I, L89M, I93L  
  1195_2127 None    T12S, I15V, L19I, N37S, R41K, L63P, H69K, V77I, L89M, I93L  
  1195_1467 None    T12S, I15V, L19I, N37S, R41K, L63P, H69K, V77I, L89M, I93L  
  1195_1680 None    T12S, I15V, L19I, N37S, R41K, L63P, H69K, V77I, L89M, I93L  
1237 1237_0237 None    T12S, I15V, L19I, M36I, R41K, Q61E, H69K, T74S, L89M, I93L  
  1237_2118 None    T12S, I15V, L19I, M36I, R41K, Q61E, H69K, T74S, V75VI, L89M, I93L  
1282 1282_0280 None    T12S, I15V, L19V, M36I, R41K, K43R, Q61E, L63P, H69K, L89M, I93L  
  1282_0525 None    T12S, I15V, L19I, M36I, R41K, K43R, Q61E, L63P, H69K, T74TA, L89M, I93L  
1447 1447_0458 None    T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, I93L  
  1447_2037 None    T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, I93L  
1467 1467_0493 None    I15V, L19I, M36I, R41K, L63S, H69K, T74S, L89M, I93L  
  1467_1383 None    K14R, I15V, L19I, M36I, R41K, L63S, H69K, L89M, I93L  
  1467_1415 None    K14R, I15V, L19I, M36I, R41K, L63S, H69K, L89M, I93L  
  1467_1693 None    K14R, I15V, L19I, M36I, R41K, L63S, H69K, L89M, I93L  
1497 1497_0550 None    T12S, I15V, L19I, M36I, R41K, H69K, L89M, I93L  
  1497_1965 None    T12S, I15V, L19I, M36I, R41K, H69K, L89M, I93L  
  1497_2975 None    T12S, I15V, L19I, M36I, R41K, D60DE, Q61QE, H69K, L89M, I93L  
1599 1599_0566 None    T12S, N37S, R41K, D60E, Q61E, L63P, H69K, V77I, L89M, I93L  
  1599_2995 None    T12S, N37S, R41K, L63P, H69K, V77I, L89M, I93L  
1604 1604_0753 None    I15V, L19I, M36L, D60E, L63S, H69K, L89M, I93L  
  1604_5370 None    I15V, L19I, M36I, D60E, H69K, L89M, I93L  
1617 1617_9067 None    Q18E, K20R, M36I, R41K, Q61E, H69K, L89M, I93L  
1624 1624_0829 None    T12S, I15V, L19I, E35ED, M36I, R41K, D60E, L63LP, H69K, L89M, I93L  
  1624_2400 None    T12S, I15V, L19I, M36I, R41K, D60E, L63P, H69K, L89M, I93L  
  1624_7985 None    T12S, I15V, L19I, M36I, R41K, D60E, L63P, H69K, L89M, I93L  
  1624_3549 None    T12S, I15V, L19I, M36I, R41K, D60E, L63P, H69K, L89M, I93L  
  1624_0542 None    T12S, I15V, L19I, M36I, R41K, D60E, L63P, H69K, L89M, I93L  
1646 1646_3858 None    L10I, T12S, I15V, L19I, M36I, R41K, D60E, Q61E, L63PS, I64IL, H69K, L89M, I93L  
1708 1708_5064 None    I15V, L19I, K20R, M36L, N37S, L63T, H69K, V77I, L89M, I93L  
1891 1891_1827 None    T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89LM, I93L  
  1891_0851 None    T12S, I15V, L19I, M36I, R41K, L63P, H69K, I93L  
1898 1898_1854 None    T12S, I15V, L19I, M36I, R41K, I62V, L63V, H69K, A71T, L89M, I93L  
  1898_4401 None    L10I, T12S, I13V, I15V, L19I, M36I, R41K, I62V, L63V, H69K, A71T, L89M, I93L  
2051 2051_2459 None    T12S, I15V, L19I, M36I, R41K, L63IV, H69K, L89M, I93L  
  2051_6489 None    T12S, I15V, L19I, M36I, R41K, L63IV, H69K, L89M, I93L  
2131 2131_4154 None    T12S, I15V, L19V, M36I, R41K, L63LP, H69K, I93L  
2146 2146_1455 None    I15IV, G17D, L19V, M36I, N37K, R41K, L63LP, H69K, L89M, I93L  
  2146_5408 None    I15V, G17D, L19V, M36I, N37K, R41K, I62IV, H69K, L89M, I93L  
2314 2314_2906 None    L10V, G16A, E35D, M36I, N37E, D60E, Q61G, C67E, H69K, K70KR, I72IV, V77I, L89M  
  2314_5524 None  M46MI  L10V, G16A, E35D, M36I, N37E, D60E, Q61G, C67E, H69K, K70R, V77I, L89M  
  2314_4328 None    L10V, G16A, E35D, M36I, N37E, D60E, Q61G, C67E, H69K, K70R, V77I, L89M