<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Lataillade (2007)
Title Natural polymorphism of the HIV-1 integrase gene and mutations associated with integrase inhibitor resistance.
Citation Antivir Ther
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 66
NumPts 66
Subtype B, Unknown


Clinical IN Isolates

01-2405 ML_01-2405 None    D6DE, E11D, I72V, V110X, I113X, S119G, T124X, T125V, D202X, I203ILV, K211X, K215X, K219KN, K240X K111APST, L213LIV, Q214QLPR, W243WGR, S255SINT, D256DAGV 
01-2749 ML_01-2749 None    Q9QH, E10A, M50I, I72V, G163E E11EAGV, K14KIRT, N18Y 
01-2750 ML_01-2750 None   Q146QH E10A, M50I, I72V, T122X, S123X, T124X, K136KN, I161X, I162X, G163E, T174TA, I200X T125LMV, K188KI, G197GAEV, R199RIKT, V201VAEG 
01-2901 ML_01-2901 None    A21S, M22L, L28I, V37I, S39C, L45I, S57SR, I72T, L101I, T125V, K136HQ, A205T, L234V K46KIRT 
01-3046 ML_01-3046 None    R20K, V31I, M50IKRT, D64X, C65X, T66X, L68X, E69X, G70X, I72V, Y99F, T124A, T206S L63LF, H67HLPR 
01-3751 ML_01-3751 None   F121FS E11D, D25E, V31I, I72V, S119P, T122I, T124A, M154L, V201I  
02-1137 ML_02-1137 None    E10ED, E11D, S24SN, V32VI, D41DN, M50MI, K71KQ, I72IV, L101I, T112TA, S119SR, T122TI, T125TA, K173KR, V201VI, A205AT Y271YDHN 
02-1148 ML_02-1148 None    E11D, S24N, D25E, V31I, S57SR, V201I  
02-1337 ML_02-1337 None    E11D, M50I, K111T, I113V, T124S, F181L, V201I, T206S, I208L, D256E Y15Y*, H16HLPR, P109PR, V110VE, V281LM 
02-1435 ML_02-1435 None    R20K, A23V, I72V, L101I, T124A, M154L, F181L, V201I, T206S, K219KR, Y227F, E246ED, S255N, D256E  
02-1456 ML_02-1456 None    S17SN, I72V, T124A, K211Q  
02-1838 ML_02-1838 None   T97TA D6E, E10D, V31I, L45Q, I72V, I84M, Y99H, L101I, T124A, V201I, I220V, D253E K42KI, A98GR, K266KIRT, I267IM 
02-1890 ML_02-1890 None   G163QR V201I  
02-2194 ML_02-2194 None    E11D, S24N, D25E, V32I, V201I, S230N, L234I S283SCGR, Q285QLPR 
02-2420 ML_02-2420 None    I72V, L101V, T124N, M154L, V201I, K219N, N222K, S230N, A265V S123ST, K188KIRT 
02-2434 ML_02-2434 None    V31I, T125V, K211KN, E212EAGV, L213X, N254NK, S255X K240KMRT, L241LHPR, D256AEGV 
02-2495 ML_02-2495 None    V31X, V32X, A33X, K34X, E35X, I72V, S230N, I251IL, A265V V225C 
02-2532 ML_02-2532 None    E11D, K34R, L101LI, K111T, S119A, T125V, V201VI, Y227F, D232E, N254K, S255G H12HQ, Q285QP, E287EAGV 
02-3003 ML_02-3003 None    D6DE, K7KI, E10D, E11D, S17T, I72V, I84M, L101I, I113IV, T124A, T125A, K156N, A205T, T218S Q285QR 
02-3442 ML_02-3442 None    E10D, V31I, L101I, N155X, K156X, E157ED, L158X, K160X, K188KN, D202X, N254X, S255X, Y271X L102LF, G134GRW, I200IKRT, E212ED, L213LPQR, D256AEGV, D270DAGV 
03-4331 ML_03-4331 None    D6E, E10D, K14R, V32I, S57N, I72V, L101I, I113V, S119P, T122I, T124N, T125TP, V201I, T206S K7KN, S283G 
03-5093 ML_03-5093 None    L45I, L101I, T124A, G163E, K211R Q285QLPR 
03-5141 ML_03-5141 None   L74LMV S24N, M50L, L101I, K173R, V176L, K211R L104LF 
03-5164 ML_03-5164 None    S24SG, T112I, I113V, T125A, G163E, V201I, K211R, D253H L101LP, H114HLPR, V126C 
03-5187 ML_03-5187 None    K7Q, T124N, T125A, V126L, M154I, V201I, I220V T112TP 
03-5355 ML_03-5355 None    V31I, I72V, E96EG, S119T, V126M, E157Q, K160Q, G193D, S195C, V201I, K211R, D256E, A265V, I268L N254NIST 
03-5476 ML_03-5476 None    S17N, M50T, T112I, I113V, T124S, T125A, V201I, T218I, D256E  
05-4014 ML_05-4014 None    M22I, S39C, I72V, V201I, K211T, T218S, Q221E, S230N E170ED, Q209QH 
10-7505 ML_10-7505 None    D6E, E11D, S17C, L101LI, S119SR, T124S, V201VI, K211KR, T218TS, Y227YF, D256E, A265E K266KT 
17-3001 ML_17-3001 None    E10D, Y83YF, L101I, T124N, T125V, I135V, G163V, V201I, T206S, I220F I89IF, Q252KT 
27B ML_27B None    V31I, M50I, L101I, T124A, T125A, I135V, K156N, G193R, T206S, Y227F, L234I, A265V  
38-4664 ML_38-4664 None    S17N, V31I, I72V, T124N, V201I, I220L, Y227F, D256E E69EG 
456-a ML_456-a None    E11D, A23AV, V31I, K111T A8APST 
46-6444 ML_46-6444 None    E11D, R20K, L45Q, I72V, G193E, S195T, D278A  
46-7038 ML_46-7038 None    K7R, S17N, I72V, I113V, T124A, T125A, V126VLM, K156N, I162V, Q216N, I220M, Y227F, S255N N254T, D286DAGV 
464a ML_464a None    S17X, I72X, T124A, R262RK H16HQ, D286DAGV, E287EAGV 
47-2933 ML_47-2933 None    D6E, K14R, S24G, V32I, I72V, V201I  
48-1275 ML_48-1275 None    K34R, I72V, L101I, T206S, A265V  
48-6203 ML_48-6203 None   L68LIV K7R, S17N, V31VIL, I72V, I113V, T124A, T125A, V126VLM, K156N, I162V, Q216N, I220M, Y227F, S255N N254T, R262RG, D286DAGV 
482-009 ML_482-009 None    S17N, M50IT, I72V, S123SG, T124A, T125V, G163E, Y227F, D253HY, S255N, D256E  
482-014 ML_482-014 None    S17N, T124A, K156N, G163Q, V201I, T218S  
482-023 ML_482-023 None    D6E, S17N, S119A, T124N, V126M, I135V, K156N, V201I, T206S, K211R, E212Q, K215N D288N 
482-079 ML_482-079 None    S17N, T124N, T125V, I135V, G163E, V201I, N254Q, D256E  
482-104 ML_482-104 None    V31I, G106A, S119T, T124A, D167E, V201I, I203X, I204X, A205S, D207X, K211R, K266X, I267X, I268X, R269X G82G*R, T174TIKR, D202DAGV, T206*LS, I208IKRT, L241LHPR, Q252QLPR, D253DAGV, A265APST 
485-7a ML_485-7a None    E10ED, E11ED, V31I, M50T, I72V, L101LI, K111AT, I113IV  
49-0974 ML_49-0974 None    E11ED, A21AS, A23AV, S24SG, V37VI, L101I, K111KR, T112A, I113IV, T125A, S230N  
490-a 490-a None    E11D, S24N, D25E, I72V, V151X, E152X, S153X, M154X, V201I, L213X, Q216X, I217X, N254X, S255X, D256DE, I257ILV, R269X E13EK, V31IR, N144NK, Q214QLPR, K215DHNY, T218TAPS, L242LHPR, W243W*LS, V260VAEG, A265AEGV, D270DAGV, Y271YCFS 
491-a ML_491-a None    D41X, Q44X, L45X, K46X, I72V, G193E, T206S, I208L, S230N, D279N K42KN, G47GAEV, E48E*KQ, P233PR, W235WG, V281M 
51-2919 ML_51-2919 None    E11D, S24SN, F26FY, G70E, I72IV, S119R, T124N, T125A, V201I S283G, R284RG, E287EAGV 
53-9028 ML_53-9028 None    V31I, M50I, L101LI, T124A, T125A, I135V, K156N, G193R, T206S, Y227F, L234I, A265V  
58-8786 ML_58-8786 None    Q9QP, E10D, E11EG, I72V, T124A, D232N H16HP 
58B ML_58B None    S17N, I72V, T124N, M154I, D256DE L2LF, K7KN, V31V*EL 
60-7734 ML_60-7734 None    D6E, E10D, T124NS, T218S R284G 
61-8272 ML_61-8272 None    T125A, K156N, H171L, V201I  
63B ML_63B None    S17N, T124N, T125V, I135V, G163E, V201I, N254Q, D256E  
64-5856 ML_64-5856 None    E10D, V31I, T124N, T125A, I135V, K219N, N222K, S230N S283SG 
64B ML_64B None    E10D, M50I, I72V, A80S, L101I, T206S  
65B ML_65B None    E10D, M50I, I72V, A80S, L101I, T206S Q285QLPR 
66B ML_66B None    L68X, I72V, T124A, V151X, K211T, E212X, S230N, L241X  
71-3849 ML_71-3849 None    S17SN, L101LI, I113IV, K156N  
71-8113 ML_71-8113 None    E11D, S24N, F26Y, G70E, S119R, T124N, T125A, V201I, I251IL S283G, Q285QP, D286G 
72-3364 ML_72-3364 None    L101I, T124A, T125A, Q216H S17KN 
85-7935 ML_85-7935 None    I72V, T112I, I113V, T122I, T124N, T125A, F181L, I182V, V201I, L234I  
87-5136 ML_87-5136 None    E10D, E11D, A21T, D25E, I72V, S119P, T122I, T125A, F181Y, V201I  
94-5629 ML_94-5629 None    V31VI, I72V, Q216H, Q221S, N222NT K7KN, L213LP 
96-5316 ML_96-5316 None    A23V, L101I, S119P, H171Q, Q177QL