Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

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References

Author Vingerhoets (2004)
Title Antiviral Activity of TMC125 against a Panel of Site-directed Mutants Encompassing Mutations Observed in vitro and in vivo
Citation unpublished
SelectedGene RT
SelectedType Lab
NumIsolates 4

Lab RT Isolates (including Susceptibility Data)


IsolateNRTIDRMsNNRTIDRMsOther MutationsMethodDrugResultFold Res.
179F+181C  V179F, Y181C K122E, F214L, A272P, K277R, A376T, A400T, D460N, S468T, H483Y, K512Q, S519N Antivirogram ETR  129.0 
HXB2-181I  Y181I K122E, F214L, A272P, K277R, A376T, A400T, D460N, S468T, H483Y, K512Q, S519N Antivirogram ETR  12.5 
HXB2-181V  Y181V K122E, F214L, A272P, K277R, A376T, A400T, D460N, S468T, H483Y, K512Q, S519N Antivirogram ETR  15.1 
HXB2-227C  F227C K122E, F214L, A272P, K277R, A376T, A400T, D460N, S468T, H483Y, K512Q, S519N Antivirogram ETR  10.1 

The Team

The Data