Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

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References

Author Brillant (2004)
Title In vitro Resistance Development for a second generation NNRTI: TMC125
Citation unpublished
SelectedGene RT
SelectedType Lab
NumIsolates 7

Lab RT Isolates (including Susceptibility Data)


IsolateNRTIDRMsNNRTIDRMsOther MutationsMethodDrugResultFold Res.
Pas2  E138K K122E, I195M, F214L, A272P, K277R, A376T, A400T, D460N, S468T, H483Y, K512Q, S519N     
Pas3  E138K, Y188H K122E, F214L, A272P, K277R, A376T, A400T, D460N, S468T, H483Y, K512Q, S519N MTT-local EFV  1.9 
       MTT-local ETR  3.0 
Pas4 T69P, L74S E138K, Y188H K122E, F214L, M230I, A272P, K277R, A376T, A400T, D460N, S468T, H483Y, K512Q, S519N     
Pas5  V179F, Y181C T39A, K122E, F214L, K263E, N265H, A272P, K277R, A376T, A400T, D460N, S468T, H483Y, K512Q, S519N     
Pas6  V179F, Y181C K122E, F214L, A272P, K277R, A376T, A400T, D460N, S468T, H483Y, K512Q, S519N MTT-local EFV  9.4 
       MTT-local ETR  733.0 
Pas7  V179F, Y181C K122E, S163R, T165A, F214L, A272P, K277R, A376T, A400T, D460N, S468T, H483Y, K512Q, S519N     
Pas8  V179F, Y181C K122E, A272P, K277R, A376T, A400T, D460N, S468T, H483Y, K512Q, S519N     

The Team

The Data