<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Su (2007)
Title In vitro selection and characterization of viruses resistant to R1206, a novel nonnucleoside reverse transcriptase inhibitor.
Citation IHDRW 2007
SelectedGene RT
SelectedSpecies HIV1
SelectedType Lab
NumIsolates 11
Lab Parent Strain HXB2


Lab RT Isolates (including Susceptibility Data)


IsolateNRTIDRMsNNRTIDRMsMethodDrugFold Res.
106A+227C  V106A, F227C Antivirogram EFV 33 
     Antivirogram ETR 1.0 
     Antivirogram RPV 14 
106A+227C+1  V106A, F227C, M230L Antivirogram EFV >167 
     Antivirogram ETR 46 
     Antivirogram RPV 783 
138K+181I  E138K, Y181I Antivirogram EFV 1.0 
     Antivirogram ETR 51 
     Antivirogram RPV 246 
179F+181C  V179F, Y181C Antivirogram EFV 2.0 
     Antivirogram ETR 93 
     Antivirogram RPV 7.0 
181I+230L  Y181I, M230L Antivirogram EFV 10 
     Antivirogram ETR >114 
     Antivirogram RPV >1,000 
227C+230L  F227C, M230L Antivirogram EFV 85 
     Antivirogram ETR 19 
     Antivirogram RPV 48 
LAI-106A  V106A Antivirogram EFV 3.0 
     Antivirogram ETR 1.0 
     Antivirogram RPV 1.0 
LAI-138K  E138K Antivirogram EFV 1.0 
     Antivirogram ETR 2.0 
     Antivirogram RPV 2.0 
LAI-181C  Y181C Antivirogram EFV 2.0 
     Antivirogram ETR 2.0 
     Antivirogram RPV 3.0 
LAI-181I  Y181I Antivirogram EFV 1.0 
     Antivirogram ETR 1.0 
     Antivirogram RPV 1.0 
LAI-230L  M230L Antivirogram EFV <1.0 
     Antivirogram ETR <1.0 
     Antivirogram RPV <1.0