Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

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References

Author Andries (2004)
Title TMC125, a novel next-generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1
Citation AAC
SelectedGene RT
SelectedType Lab
NumIsolates 6

Lab RT Isolates (including Susceptibility Data)


IsolateNRTIDRMsNNRTIDRMsOther MutationsMethodDrugResultFold Res.
100I  L100I K122E, F214L, A272P, K277R, M357T, A376T, A400T, N447S, D460N, S468T, S519N Pauwels ETR  3.0 
100I+103N  L100I, K103N K122E, F214L, A272P, K277R, M357T, A376T, A400T, N447S, D460N, S468T, S519N Pauwels ETR  19.0 
103N  K103N K122E, F214L, A272P, K277R, M357T, A376T, A400T, N447S, D460N, S468T, S519N Pauwels ETR  1.0 
103N+181C  K103N, Y181C K122E, F214L, A272P, K277R, M357T, A376T, A400T, N447S, D460N, S468T, S519N Pauwels ETR  4.0 
181C  Y181C K122E, F214L, A272P, K277R, M357T, A376T, A400T, N447S, D460N, S468T, S519N Pauwels ETR  7.0 
188L  Y188L K122E, F214L, A272P, K277R, M357T, A376T, A400T, N447S, D460N, S468T, S519N Pauwels ETR  5.0 

The Team

The Data