<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author McGrath (2007)
Title Antiviral efficacy and emergent PI substitutions in treatment-naive subjects receiving atazanavir +/- ritonavir-based HAART in subtype b and non-type b HIV-1 infection.
Citation IHDRW 2007
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 20
NumPts 10
Subtype B, C


Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
DMG_1 None    T12S, I15V, L19I, M36I, R41K, L63PS, H69K, I93L  
  DMG_1a RTV, ATV 48  N83ND T12S, I15V, L19I, M36I, R41K, L63PS, H69K, I93L  
10 DMG_10 None    L10LI, I13IV, L33V, N37X, R41RK, I62V, L63APS, I64V, C67CY, H69HQ  
  DMG_10a ATV 48   L10LI, I13IV, L33V, N37X, R41RK, I62V, L63APS, I64V, C67CY, H69HQ  
DMG_2 None    T12S, I15V, L19I, K20R, E35D, M36I, R41K, H69K, L89M, I93L  
  DMG_2a RTV, ATV 48   T12S, I15V, L19I, K20R, E35D, M36I, R41K, H69K, L89M, I93L  
DMG_3 None    E35D, M36I, R57K, I62V, L63P, I64IL, A71AV, I72IV, V77VI, P79PAS, I93IL  
  DMG_3a ATV 48   E35D, M36I, R57K, I62V, L63P, I64IL, A71AV, I72IV, V77VI, P79PAS, I93IL  
DMG_4 None    L10LI, P39PS, L63P, V77I, I93L  
  DMG_4a ATV 48 I50IL  L10LI, E34EQ, P39PS, L63P, V77I, I93L  
DMG_5 None    L10I, T12TK, I13IV, N37X, L63P, I64IV, I93L  
  DMG_5a ATV 48 I50IL G73GS L10I, T12TK, I13IV, N37X, L63P, I64IV, A71AV, T74TA, I93L  
DMG_6 None    T12S, I15V, L19I, M36IT, R41K, K43KR, L63P, H69K, L89LM, I93L  
  DMG_6a ATV 48   T12S, I15V, L19I, M36IT, R41K, K43KR, L63P, H69K, L89LM, I93L  
DMG_7 None    L10I, I13V, G16GE, L19T, K20R, M36I, R41K, L63AITV, I64IM, E65D, H69K, L89M, I93L  
  DMG_7a ATV 48   L10I, I13V, G16GE, L19T, K20R, M36I, R41K, L63AITV, I64IM, E65D, H69K, T74TA, L89M, I93L  
DMG_8 None    L10I, I15V, G16E, E35D, L63H, V77VI, L89M  
  DMG_8a ATV 48 I50L, N88NS L33LF L10I, I15V, G16E, K20KIT, E35D, M36MV, L63H, A71AV, V77VI, L89M L23LP 
DMG_9 None   V11IT L10I, E35D, Q61E, I62V, L63P, I64L, A71V, I72T, V77I, P79AS, I93L  
  DMG_9a ATV 48  V11IT L10I, E35D, Q61E, I62V, L63P, I64L, A71V, I72T, V77I, P79AS, I93L