<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Kurle (2007)
Title Emergence of NNRTI drug resistance mutations after single-dose nevirapine exposure in hiv type 1 subtype C infected infants in India.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
NumIsolates 32
NumPts 28
Subtype C

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
NVP-1 1-M2 None NVP  V179D E28K, K32E, V35T, E36A, T39N, S48T, V60I, D121C, K122E, I135V, S162C, E169K, K173E, Q174R, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, K311R, G335D, R356K, G359T, T377M, K390R, A400T, E404D  
NVP-10 10-D2 None None   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, S162A, K166R, K173A, D177E, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, G335D, R356K, G359T, E370X  
  10-M2 None NVP   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, S162A, K166R, K173A, D177E, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, G335D, R356K, G359T R78RG 
NVP-12 12-M2 None NVP  Y188C V35T, T39D, S48T, V60I, D121Y, K122E, I135T, S162A, K173A, D177E, T200E, Q207G, V245Q, A272P, K277R, T286A, V292I, I293V, P313Q, G335D, R356K, M357Q, G359T  
NVP-13 13-D2 None None   V35T, T39D, S48T, V60I, D121H, K122E, I135R, S162C, K173T, D177E, T200A, Q207E, R211K, V245Q, A272P, V276I, K277R, E291D, V292I, I293V, G335D, R356K, G359T  
  13-M2 None NVP   V35T, T39D, S48T, V60I, D121H, K122E, I135R, S162C, K173T, D177E, T200A, Q207E, R211K, V245Q, A272P, V276I, K277R, E291D, V292I, I293V, G335D, R356K, G359T  
NVP-16 16-D2 None None   V35T, E36A, T39E, S48T, V60I, D121Y, K122E, I135R, S162C, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335E, R356K, G359T  
  16-M2 None NVP  Y181C V35T, E36A, T39E, S48T, V60I, D121Y, K122E, I135R, S162C, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335E, R356K, G359T K13KE 
NVP-19 19-M2 None NVP  Y181C V35T, T39D, S48T, V60I, D121H, K122E, K173A, Q174R, D177E, I178M, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, G335D, R356K, G359T, T369S, T377M, E396X, A400T, E404D  
NVP-21 21-D2 None None   V35I, T39D, S48T, V60I, D121Y, K122E, I135T, K166R, K173A, D177E, T200A, Q207E, R211K, F214L, V245Q, A272P, K277R, L283I, R284K, E291D, V292I, I293V, G335D, R356K, M357R, G359T, T377M, K385R, K390R, A400T, E404D, E432D, A437V  
NVP-22 22-D2 None None   K32R, V35T, E36A, T39D, S48T, V60I, K101R, D121Y, K122E, I135T, S162A, K173A, Q174R, P176S, D177E, I178L, T200A, Q207K, F214L, V245Q, A272P, R284K, T286A, E291D, V292I, I293V, V317A, R356K, G359T, T377M, K390R, A400T, E404D, E432I  
NVP-23 23-D2 None None   K32R, V35T, E36A, T39D, S48T, V60I, D121Y, K122E, S162A, K166R, K173A, Q174R, D177E, I178L, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E297A, Q334H, G335D, R356K, G359T, V365I  
NVP-28 28-D2 None None   T7I, V35T, E36A, T39E, S48T, K102R, K122E, D123N, S162C, K166R, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, P294T, Q334H, G335D, N348P, R356K, G359T  
NVP-29 29-D2 None None   V8I, V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135V, K166R, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, V317A, G335D, R356K, G359T  
NVP-3 3-M2 None NVP   V8I, V35T, T39N, S48T, V60I, K103R, D121Y, K122E, K173A, D177E, T200A, Q207K, V245Q, A272P, K277R, E291D, V292I, I293V, P294L, V317I, I326V, R356K, G359T, A360T, A376S, T377M, K390R, A400T, E404D, E432D, V435A  
NVP-30 30-D2 None None   V35T, E36A, T39D, S48T, V60I, K101R, D121H, K122E, I135T, I142V, K173A, D177E, I178V, T200A, Q207E, V245Q, A272P, K277R, V292I, I293V, V314I, V317A, G335D, R356K, G359T  
NVP-32 32-D2 None None   T39D, S48T, V60I, K122E, I135R, K166R, K173A, P176S, T200A, E204K, H208Y, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, L301I, V317A, G335D, R356K, G359T  
NVP-34 34-M2 None NVP   V35K, E36A, T39D, S48T, V60I, D121Y, K122E, K173A, Q174R, D177E, I178L, E194A, T200A, I202V, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E297A, I326V, R356K, G359T  
NVP-36 36-M2 None NVP   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135T, S162A, K173E, D177E, T200A, Q207E, V245Q, A272P, K277R, K281R, T286A, E291D, V292I, I293V, E297A, G335D, R356K, G359T  
NVP-37 37-M2 None NVP   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, S162A, K166R, K173A, T200A, Q207E, V245Q, A272P, K277R, E291D, V292I, I293V, V317A, Q334H, G335D, R356K, G359T  
NVP-38 38-D2 None None  V179D V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135R, S162A, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, G335D, R356K, G359T  
  38-M2 None NVP  V179D V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135R, S162A, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, G335D, R356K, G359T  
NVP-39 39-D2 None None   E28K, K32E, V35T, T39N, S48T, V60I, K102R, K122E, K126R, K166R, K173T, Q174R, D177E, I178M, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317A, G335D, R356K, G359T  
NVP-4 4-D2 None None  K101E V35T, E36A, T39E, S48T, V60I, D121Y, K122E, I135T, S162C, K166R, K173A, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, A272P, K277R, T286V, E291D, V292I, I293V, V317A, G335D, P345Q, R356K, G359T D185G 
NVP-40 40-M2 None NVP   V35T, E36A, T39E, S48T, V60I, D121Y, K122E, I135T, S162C, K166R, K173A, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, A272P, K277R, T286V, E291D, V292I, I293V, V317A, G335D, P345Q, R356K, G359T  
NVP-43 43-D2 None None   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E297A, V317A, G335D, E344D, R356K, G359T  
NVP-44 44-D2 None None   V35T, E36A, T39D, S48T, D121Y, K122E, T165I, K173A, D177E, T200A, Q207V, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, Q334E, G335D, R356K, M357I, G359T, K366R  
NVP-45 45-D2 None None   V35T, E36A, T39D, S48T, V60I, I135T, S162A, K173A, D177E, T200A, Q207E, V245Q, A272P, K277R, K281R, T286A, E291D, V292I, I293V, E297A, G335D, K347R, R356K, G359T  
NVP-6 6-D2 None None   V35T, E36A, T39E, S48T, K122E, D123G, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, V317A, Q334H, G335D, R356K, G359T  
NVP-7 7-M2 None NVP   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135T, K166R, K173A, Q174K, D177E, I178L, V189I, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, E297A, G335D, R356K, G359T  
NVP-8 8-D2 None None   V35T, T39N, S48T, V60I, D121Y, K122E, S162A, K173A, T200A, Q207E, V245H, A272P, K277R, E291D, V292I, I293V, G335D, R356K, G359T, A400T, E404D, V435A  
NVP-9 9-D2 None None   V35T, T39E, S48T, V60I, D121Y, K122E, D123E, I135R, S162A, K173T, D177E, Q207A, R211K, V245E, A272P, K277R, E291D, V292I, I293V, K311R, G335D, R356K, M357R, G359T, T377M, A400T, E404D  

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