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Enter the number and order of specific drug combinations of interest, as well as the species, group and subtype desired. Data will be displayed in a table listing major and minor mutations found in isolates with matching treatment histories and original literature references. Complete mutation lists, treatment histories and subtype information may be retrieved by selecting the appropriate box under 'Additional Output Options'. Individual and composite alignments will also be available.
To retrieve RT sequences from persons receiving a selected antiretroviral therapy:
- Enter the treatment requirements:
- # of nucleoside RT inhibitors (NRTIs)
- # of non-nucleoside RT inhibitors (NNRTIs)
- specific combinations of RT inhibitors
- Enter the species: HIV1, HIV2, or NHPL (Non-Human Primate Lentivirus)
- Enter the group for HIV1: Main, CPZs or O
- Enter the subtype for HIV1, Main: All subtypes, B, non-B, or a specific non-B subtype
- Optional modifications to the type of data that are returned:
- Complete treatment history (vs default listing of NRTIs and NNRTIs received)
- Complete mutation list (vs default listing of NRTI mutations and NNRTI mutations)
- Subtype
Abbreviations:
- 3TC = lamivudine, ABC = abacavir, FTC = emtricitabine, AZT = zidovudine, D4T = stavudine,
DDC = zalcitabine, DDI = didanosine, DLV = delavirdine, EFV = efavirenz, NVP = nevirapine,
TDF = tenofovir
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