<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Detailed Protease Phenotype Query

 CodonAmino Acid
1st
2nd
3rd
4th
5th
6th
With No Other PI Major Mutations
Drugs
FPV
IDV
NFV
RTV
SQV
LPV
ATV
TPV
DRV
All
Susceptibility Test Methods
 
Reset


Enter up to six amino acid positions with optional mutations to retrieve published drug susceptibility data. User can specify whether the retrieved sequences need to exactly match the entered mutations at major drug resistance mutations. Leaving this box unchecked will retrieve sequences that may include additional major mutations. Individual antiretroviral drugs can be selected, or susceptibility data can be retrieved for all members of a drug class. User can specify the susceptibility test method if desired. Alternatively, complete HIVDB phenotype datasets may be downloaded here.

To retrieve published drug susceptibility data for protease isolates with selected mutations:

  • Enter one or more specific amino acid positions with optional mutations
  • Enter whether the retrieved sequences need to exactly match the entered mutations at major PI mutations
  • Enter the drugs used for susceptibility testing
  • Enter one or more susceptibility test methods
    • All, Antivirogram (Virco, Belgium; used to be named as "Virco"), PhenoSense (Monogram, South San Francisco; used to be named as "Virologic")
Abbreviations:
  • FPV = fosamprenavir,  ATV = atazanavir,  IDV = indinavir,  
    LPV = lopinavir,  NFV = nelfinavir,  RTV = ritonavir,  SQV = saquinavir,  TPV = tipranavir