Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Home Genotype-RX Genotype-Pheno Genotype-Clinical HIVdb Program

Protease Mutation Profile

Gene PR
Position N83
Subtype All
Compared With Untreated
IncludeMixture Yes
CountBy Person

Mutation rates that differ significantly between treated and untreated isolates (p <=0.05 after Yates's correction) are indicated in yellow. Baseline mutation frequencies of untreated viruses are indicated in green. The number of sequences in each category is indicated. This form correlates the likelihood of mutation at any amino acid position with treatment history. Note: About 50% of untreated isolates belong to Non-B subtypes. In contrast, a much smaller proportion of treated isolates belong to Non-B subtypes.

 
 Untreated Chi-square with Yates's correction
p <= 0.05
 
 

N83D

AAPINumSeqNumMut% Mutantp
D02466160.00 
D>=18496780.900.000
DAPV480  
DIDV9680  
DLPV490  
DNFV111330.200.001
DRTV18710.500.050
DSQV2950  
DATV340  

N83S

AAPINumSeqNumMut% Mutantp
S02466140.00 
S>=18496270.300.000
SAPV480  
SIDV9680  
SLPV490  
SNFV11130  
SRTV1870  
SSQV2950  
SATV340  

N83H

AAPINumSeqNumMut% Mutantp
H024661170.00 
H>=1849620.000.213
HAPV480  
HIDV96810.100.825
HLPV490  
HNFV11130  
HRTV1870  
HSQV2950  
HATV340  

Team

Resources