Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

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Protease Mutation Profile

Gene PR
Position V75
Subtype All
Compared With Untreated
IncludeMixture Yes
CountBy Person

Mutation rates that differ significantly between treated and untreated isolates (p <=0.05 after Yates's correction) are indicated in yellow. Baseline mutation frequencies of untreated viruses are indicated in green. The number of sequences in each category is indicated. This form correlates the likelihood of mutation at any amino acid position with treatment history. Note: About 50% of untreated isolates belong to Non-B subtypes. In contrast, a much smaller proportion of treated isolates belong to Non-B subtypes.

 
 Untreated Chi-square with Yates's correction
p <= 0.05
 
 

V75I

AAPINumSeqNumMut% Mutantp
I024669890.30 
I>=18498710.800.000
IAPV480  
IIDV96810.100.293
ILPV490  
INFV1113232.000.000
IRTV18721.000.322
ISQV29510.300.670
IATV340  

V75A

AAPINumSeqNumMut% Mutantp
A024669110.00 
A>=1849810.000.298
AAPV4812.000.002
AIDV9680  
ALPV490  
ANFV11130  
ARTV1870  
ASQV2950  
AATV340  

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