Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

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Protease Mutation Profile

Gene PR
Position Y59
Subtype All
Compared With Untreated
IncludeMixture Yes
CountBy Person

Mutation rates that differ significantly between treated and untreated isolates (p <=0.05 after Yates's correction) are indicated in yellow. Baseline mutation frequencies of untreated viruses are indicated in green. The number of sequences in each category is indicated. This form correlates the likelihood of mutation at any amino acid position with treatment history. Note: About 50% of untreated isolates belong to Non-B subtypes. In contrast, a much smaller proportion of treated isolates belong to Non-B subtypes.

 
 Untreated Chi-square with Yates's correction
p <= 0.05
 
 

Y59F

AAPINumSeqNumMut% Mutantp
F024666270.10 
F>=1849760.000.436
FAPV470  
FIDV96810.100.660
FLPV490  
FNFV111320.100.821
FRTV1870  
FSQV2950  
FATV340  

Y59H

AAPINumSeqNumMut% Mutantp
H024666130.00 
H>=1849710.000.201
HAPV470  
HIDV9680  
HLPV490  
HNFV11130  
HRTV1870  
HSQV2950  
HATV340  

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