Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

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Protease Mutation Profile

Gene PR
Position G40
Subtype All
Compared With Untreated
IncludeMixture Yes
CountBy Person

Mutation rates that differ significantly between treated and untreated isolates (p <=0.05 after Yates's correction) are indicated in yellow. Baseline mutation frequencies of untreated viruses are indicated in green. The number of sequences in each category is indicated. This form correlates the likelihood of mutation at any amino acid position with treatment history. Note: About 50% of untreated isolates belong to Non-B subtypes. In contrast, a much smaller proportion of treated isolates belong to Non-B subtypes.

 
 Untreated Chi-square with Yates's correction
p <= 0.05
 
 

G40R

AAPINumSeqNumMut% Mutantp
R024669110.00 
R>=1849730.000.956
RAPV480  
RIDV96810.100.944
RLPV490  
RNFV111210.000.975
RRTV18710.500.171
RSQV2950  
RATV340  

G40E

AAPINumSeqNumMut% Mutantp
E024669110.00 
E>=1849720.000.597
EAPV480  
EIDV9680  
ELPV490  
ENFV11120  
ERTV1870  
ESQV2950  
EATV340  

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