Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

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Protease Mutation Profile

Gene PR
Position V32
Subtype All
Compared With Untreated
IncludeMixture Yes
CountBy Person

Mutation rates that differ significantly between treated and untreated isolates (p <=0.05 after Yates's correction) are indicated in yellow. Baseline mutation frequencies of untreated viruses are indicated in green. The number of sequences in each category is indicated. This form correlates the likelihood of mutation at any amino acid position with treatment history. Note: About 50% of untreated isolates belong to Non-B subtypes. In contrast, a much smaller proportion of treated isolates belong to Non-B subtypes.

 
 Untreated Chi-square with Yates's correction
p <= 0.05
 
 

V32I

AAPINumSeqNumMut% Mutantp
I02503330.00 
I>=184965526.400.000
IAPV48510.400.000
IIDV967474.800.000
ILPV4912.000.000
INFV111240.300.000
IRTV18742.100.000
ISQV2950  
IATV3412.900.000

V32A

AAPINumSeqNumMut% Mutantp
A02503370.00 
A>=1849650.000.333
AAPV480  
AIDV9670  
ALPV490  
ANFV111230.200.001
ARTV1870  
ASQV2950  
AATV340  

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