Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

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Protease Mutation Profile

Gene PR
Position T31
Subtype All
Compared With Untreated
IncludeMixture Yes
CountBy Person

Mutation rates that differ significantly between treated and untreated isolates (p <=0.05 after Yates's correction) are indicated in yellow. Baseline mutation frequencies of untreated viruses are indicated in green. The number of sequences in each category is indicated. This form correlates the likelihood of mutation at any amino acid position with treatment history. Note: About 50% of untreated isolates belong to Non-B subtypes. In contrast, a much smaller proportion of treated isolates belong to Non-B subtypes.

 
 Untreated Chi-square with Yates's correction
p <= 0.05
 
 

T31P

AAPINumSeqNumMut% Mutantp
P024666270.10 
P>=1849660.000.436
PAPV480  
PIDV96810.100.660
PLPV490  
PNFV111210.000.786
PRTV18710.500.527
PSQV2950  
PATV340  

T31S

AAPINumSeqNumMut% Mutantp
S024666160.00 
S>=1849620.000.254
SAPV4812.000.010
SIDV9680  
SLPV490  
SNFV11120  
SRTV1870  
SSQV2950  
SATV340  

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