Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

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Protease Mutation Profile

Gene PR
Position D29
Subtype All
Compared With Untreated
IncludeMixture Yes
CountBy Person

Mutation rates that differ significantly between treated and untreated isolates (p <=0.05 after Yates's correction) are indicated in yellow. Baseline mutation frequencies of untreated viruses are indicated in green. The number of sequences in each category is indicated. This form correlates the likelihood of mutation at any amino acid position with treatment history. Note: About 50% of untreated isolates belong to Non-B subtypes. In contrast, a much smaller proportion of treated isolates belong to Non-B subtypes.

 
 Untreated Chi-square with Yates's correction
p <= 0.05
 
 

D29V

AAPINumSeqNumMut% Mutantp
V02466680.00 
V>=1849790.100.021
VAPV480  
VIDV9670  
VLPV490  
VNFV111210.000.854
VRTV1870  
VSQV2950  
VATV340  

D29G

AAPINumSeqNumMut% Mutantp
G024666110.00 
G>=1849720.000.597
GAPV480  
GIDV9670  
GLPV490  
GNFV11120  
GRTV1870  
GSQV2950  
GATV340  

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