Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

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Protease Mutation Profile

Gene PR
Position L23
Subtype All
Compared With Untreated
IncludeMixture Yes
CountBy Person

Mutation rates that differ significantly between treated and untreated isolates (p <=0.05 after Yates's correction) are indicated in yellow. Baseline mutation frequencies of untreated viruses are indicated in green. The number of sequences in each category is indicated. This form correlates the likelihood of mutation at any amino acid position with treatment history. Note: About 50% of untreated isolates belong to Non-B subtypes. In contrast, a much smaller proportion of treated isolates belong to Non-B subtypes.

 
 Untreated Chi-square with Yates's correction
p <= 0.05
 
 

L23I

AAPINumSeqNumMut% Mutantp
I02465680.00 
I>=184931231.400.000
IAPV480  
IIDV9670  
ILPV490  
INFV1111110.900.000
IRTV18710.500.095
ISQV29520.600.000
IATV340  

L23V

AAPINumSeqNumMut% Mutantp
V02465680.00 
V>=1849340.000.779
VAPV480  
VIDV96710.100.779
VLPV490  
VNFV11110  
VRTV1870  
VSQV2950  
VATV340  

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