MARVEL on integrase mutations at position 146
HIVdb Algorithm: Comments & Scores
Footnote:Mutation scores on the left are derived from published literature linking mutations and ARVs (the complete details can be found in the HIVdb Release Notes).
Mutation frequency according to subtype and drug-class experience.The frequency of each mutation at position 146 according to subtype and drug-class experience. Data are shown for the 8 most common subtypes. The number of persons in each subtype/treatment category is shown beneath the subtype. Mutations occurring at a frequency >0.5% are shown. Each mutation is also a hyper-link to a separate web page with information on each isolate, including literature references with PubMed abstracts, the GenBank accession number, and complete sequence and treatment records.
Phenotypes of top 10 common patterns of drug resistance mutations with mutations at position 146.Mutation pattern data is not available for Q146.
A complete summary of additional in vitro susceptibility data for viruses with Q146 obtained using other assays including the Antivirogram can be found here.